Animals may offer alternative to some gain-of-function studies

2021-06-16

Gain-of-function research that makes pathogens more potent has sparked fierce debate among scientists, some of whom say the work is necessary to understand diseases, though others say risks far outweigh benefits. In some cases, however, it may not be necessary if animal models stand in for humans in studies of zoonotic pathogens, says Michael Imperiale, a professor of microbiology and immunology and associate vice president for research and compliance at the University of Michigan.

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