SARS-CoV-2 variants affect broad range of hosts

2021-12-01

The Alpha, Beta, Gamma and Delta variants of SARS-CoV-2 have mutations in the spike protein's receptor binding domain that enable the virus to infect a broader range of species than early variants, according to a study posted prior to peer review on bioRxiv, suggesting animals could become reservoirs that allow further mutation and spillover. Research with susceptible animals can advance scientists' understanding of COVID-19, but the virus' broadening adaptability must be considered when interpreting the results of animal studies, the researchers wrote.

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