December 1, 2021
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Top Story
A PET imaging-based tool that could help detect liver inflammation in patients with non-alcoholic fatty liver disease  has been developed, according a report in Clinical Gastroenterology and Hepatology. The tool measures the rate of glucose transport from blood to liver tissue by using mathematical modeling and dynamic PET imaging.
Full Story: News Medical (11/30) 
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Rethink how you leverage imaging for R&D
Finding, curating, and organizing data can take up the bulk of a research team's time, delaying project timelines and increasing costs. But there are better ways to de-silo data, automate time-consuming processes, and accelerate breakthroughs. See how leading life sciences researchers are applying cutting-edge tools. Learn more.
Clinical News & Research
A meta-analysis and systematic review in JAMA Network Open found that intensive blood pressure reduction may not prevent dementia and cognitive decline. The researchers did not find a significant link between mild cognitive impairment or dementia, global cognitive performance and intensive BP reduction, but they did find that people in the intensive group had a reduction in cerebrovascular events without an increased risk for mortality.
Full Story: Healio (free registration) (11/30) 
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Coffee may help reduce AD risk, study finds
Researchers found that people who drank more coffee had a lower risk of developing Alzheimer's disease and of transitioning to mild cognitive impairment, the stage that typically comes before the disease. The study, published in Frontiers in Aging Neuroscience, found that higher intake of coffee seemed to slow amyloid protein accumulation in the brain.
Full Story: HealthDay News (11/30) 
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The Pfizer/BioNTech COVID-19 vaccine is not linked to an increased risk for ischemic stroke, hemorrhagic stroke, acute myocardial infarction or pulmonary embolism, according to a research letter published in JAMA. The study examined the data of approximately 3.9 million and 3.2 million adults 75 years old or older and who received one or both doses of the vaccine, respectively.
Full Story: Cardiovascular Business online (11/29) 
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Industry Report
Cytalux, or pafolacianine, a new imaging drug, gained FDA approval to enhance detection of ovarian cancer in women, particularly during surgery, to improve their chances of survival. The drug is given intravenously prior to surgery and is used in combination with an FDA-approved fluorescence imaging system.
Full Story: HealthDay News (11/29) 
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News from the Field
Due to concerns over the Omicron coronavirus variant, the Biden administration is collaborating with COVID-19 vaccine manufacturers "to develop contingency plans for modifications to vaccines or boosters if they're needed," according to White House COVID-19 response coordinator Jeff Zients. The US continues to vaccinate as many Americans as possible in the fight against COVID-19 and had administered 460.7 million doses as of Tuesday morning, while 197 million people are fully vaccinated and an estimated 41.1 million Americans have received a booster dose.
Full Story: CNN (11/30),  Reuters (11/30) 
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Health Policy
CDC recommends vaccine boosters amid Omicron concern
CDC director Dr. Rochelle Walensky said all adults should get COVID-19 booster shots six months after receiving their second dose of Moderna or Pfizer/BioNTech vaccine or two months after getting the Johnson & Johnson vaccine amid rising concern over the new Omicron variant. Walensky also urged 47 million US adults who have not been vaccinated to do so "because strong immunity will likely prevent serious illness."
Full Story: CNN (11/29),  CNBC (11/29) 
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Judge halts COVID-19 vaccine rules for health workers
A district judge in Louisiana issued a preliminary injunction Tuesday to temporarily block the CMS from enforcing COVID-19 vaccine requirements for health workers in 40 states where the rules had not already been blocked. Separately, a district judge in Kentucky also blocked the implementation of the Biden administration's vaccine requirement for government contract workers in Ohio, Kentucky and Tennessee.
Full Story: Reuters (11/30),  Forbes (tiered subscription model) (11/30) 
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Advancing Health Care
Better nudges might reduce patient alert fatigue
EHR alert fatigue probably affects patients in addition to health care professionals, and there should be a feedback loop for patients to indicate preferred times and modes of contact, writes primary care physician Fred Pelzman. There should also be an indication in patient alerts and nudges as to why the procedure is important along with a way for the patient to indicate the task has already been completed or set up an appointment, Pelzman suggests.
Full Story: MedPage Today (free registration) (11/29) 
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Identity-centric framework can curb health IT risks
Health care organizations should take an identity-centric approach to securing patient health data and minimizing risks when complying with patient data access rules, according to a white paper from the Health Information Sharing and Analysis Center. A robust identity infrastructure framework ensures only the right people have access to information through authentication, access and authorization functions; administration and governance; and proper patient matching, according to the paper.
Full Story: EHR Intelligence (11/29) 
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SNMMI is now accepting abstract submissions for its 2022 Annual Meeting, June 11-14 in Vancouver, BC, Canada. The Annual Meeting is the ideal platform for presenting your research to a global audience of your peers, while increasing your professional recognition in the field. Learn more and submit your abstract today.
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This complimentary webinar on Dec. 8 at 3 p.m. ET presents an overview of the basic principles and concepts for performing myocardial blood flow. Topics include a review of the coronary vessel anatomy, the two models used for measurement, radiopharmaceuticals, and imaging system considerations for achieving optimal image quality, acquisition and processing techniques and identification of artifacts and errors. Free for SNMMI members. Register now.
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Anne Frank,
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The news summaries appearing in SNMMI SmartBrief are based on original information from multiple internet sources and are produced by SmartBrief, Inc., an independent e-mail newsletter publisher. The items above are not selected or reviewed by SNMMI prior to publication. Questions and comments may be directed to SmartBrief at
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