Review finds variable, increasing prevalence of celiac disease | CDC: Up to 800 deaths are caused by norovirus infection every year | Study links higher BMI to risk of gallstones
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July 17, 2013
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Review finds variable, increasing prevalence of celiac disease
A review of data from 266 studies showed variable prevalence of celiac disease worldwide, ranging from 8.1 to 204 cases per 100,000 people of all ages. Rates varied by geographic location, but almost all studies that looked at trends over time found an increase in diagnoses among children. Healio (7/12)
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Guide to Healthy Living
CDC: Up to 800 deaths are caused by norovirus infection every year
Norovirus infection is responsible for about 56,000 to 71,000 hospitalizations and approximately 570 to 800 deaths in the U.S. each year, CDC researchers found. While adults older than age 65 had the highest mortality risk due to norovirus, children younger than 5 years received the most medical care, according to the report. DailyRx.com (7/10)
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Study links higher BMI to risk of gallstones
A population-based study linked increased BMI with a higher risk of gallstones, especially in women. The Danish researchers also found that patients who had greater genetic predisposition to obesity also had a higher risk of increased BMI and developing gallstones. They said the data represent one more reason "for lifestyle interventions aimed at weight loss among overweight and obese individuals in the general population." MedPage Today (free registration) (7/14)
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Excess belly fat may predict likelihood of cancer, heart disease
Excess fat in the abdomen was associated with increased risk of developing heart disease and cancer, U.S. researchers reported. The findings suggest that "abdominal fat may partially underlie the association of body fat and heart disease and cancer," study author Dr. Caroline Fox said. U.S. News & World Report/HealthDay News (7/10)
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Eating 5 servings of fruits and vegetables daily may prolong life
People who ate fewer than five servings of fruits and vegetables daily were at an increased risk of early death, according to a study of more than 71,000 people in Sweden. The risk of early death was 53% higher among those who didn't eat fruits and vegetables compared with those who got their five daily servings. The researchers said the findings held true even after accounting for gender, smoking status, physical activity, body weight and alcohol consumption. Reuters (7/11)
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Diagnosis & Treatment
Secondary cancer risk may depend on site of initial CRC
Colorectal cancer patients had a higher risk of developing a small intestine secondary cancer, according to an analysis of data from more than 170,000 patients. The risk, however, was seven times higher among patients whose original tumor was located in the ascending colon. MedPage Today (free registration) (7/15)
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Study: Whipworm therapy for Crohn's safe, well-tolerated
A double-blind multicenter study of 36 patients with Crohn's disease found one oral dose of up to 7,500 embryonated porcine whipworm eggs was safe and well-tolerated, paving the way for further efficacy testing in inflammatory bowel disease. "There is now great interest in ways that the fecal microbiome might be manipulated to treat IBD," said researcher Dr. William Sandborn, chief of gastroenterology and director of the IBD Center at University of California, San Diego. Healio (7/11)
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Study: 25% of HIV patients have repeated HCV infections
A U.K. study found almost one-quarter of HIV patients who contracted and then were cured of hepatitis C acquired second or third infections within two years. Researcher Dr. Thomas Martin of the Chelsea and Westminster Hospital in London said non-AIDS mortality caused by HCV is common, and the study indicates patients need better education about HIV/HCV co-infection, he said. Medscape (free registration) (7/11)
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Other News
Clinical Trial Monitor
A selection of U.S. based clinical trials seeking participants
Colorectal Cancer Screening for Cancer Survivors
Massachusetts, Canada. clinicaltrials.gov
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Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults With Chronic Hepatitis B (HBRN)
California, Hawaii, Maryland, Massachusetts, Michigan, Minnesota, Missouri, North Carolina, Texas, Virginia, Washington, Canada. clinicaltrials.gov
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Curcumin in Treating Patients With Familial Adenomatous Polyposis
Maryland, Puerto Rico. clinicaltrials.gov
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An Active Treatment Study to Induce Clinical Response and/or Remission With GSK1605786A in Subjects With Crohn's Disease (SHIELD-4)
Arizona, Colorado, Connecticut, Florida, Georgia, Maryland, Massachusetts, Michigan, Minnesota, Missouri, New York, North Carolina, Ohio, Oklahoma, Oregon, Pennsylvania, Utah, Virginia, Wisconsin, Australia, Austria, Belgium, Chile, Czech Republic, Denmark, Estonia, France, Germany, Greece, Hong Kong, Hungary, Israel, Italy, Japan, Netherlands, New Zealand, Poland, Portugal, Russia, Slovakia, South Korea, Spain, Switzerland, Taiwan, Ukraine, United Kingdom. clinicaltrials.gov
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Changes in Microbiome Following Fecal Microbiota Transplantation (FMT) for Recurrent or Resistant C Difficile Infection
Wisconsin. clinicaltrials.gov
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Did you know?
When your immune system turns on you
"Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body. ... There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting a diagnosis can be frustrating and stressful. Often, the first symptoms are fatigue, muscle aches and a low fever. The classic sign of an autoimmune disease is inflammation, which can cause redness, heat, pain and swelling." -- Medline Plus
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The Last Word
News and information from the American College of Gastroenterology
Obesity: Do you know your GI risks?
Do you weigh more than you should? Losing weight is more than about looking good, it is about being healthy. If your goal is to shed excess pounds, you're not alone. Millions of people suffer from obesity, which, if left untreated, could potentially lead to serious health problems. From ACG, Obesity: Do You Know Your GI Risks? will provide you information about obesity, its dangers, what you can do to improve your health, and tools and tips to help you succeed.
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SmartQuote
Right is right, even if everyone is against it, and wrong is wrong, even if everyone is for it."
-- William Penn,
British statesman and philosopher
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