Study could improve cat, human health | Researchers developing polio vaccine that contains no live virus | NIH funds effort to build a better mouse model
January 25, 2017
FBR Smartbrief
Top Story
Study could improve cat, human health
Study could improve cat, human health
(Christopher Furlong/Getty Images)
Researchers at the University of Colorado are working with staff at the Aurora Animal Shelter on a study of feline immunodeficiency virus that could expand knowledge of HIV and improve feline health. The researchers also hope to develop a noninvasive approach to sterilization that could decrease the prevalence of FIV and feral populations.
The Aurora Sentinel (Colo.) (1/18) 
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Research Breakthroughs
Researchers developing polio vaccine that contains no live virus
Researchers are working on a polio vaccine that doesn't require the use of a live polio virus, according to a study in PLOS Pathogens. Virus-like particles, or VLPs, which contain no live virus, have been used in vaccines given to rodents, and researchers say they work as well as live-virus vaccines.
The Scientist online (1/19) 
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NIH funds effort to build a better mouse model
The NIH's National Institute on Aging is funding a $25 million collaborative effort to develop mouse models that express genotypes linked to late-onset Alzheimer's disease, and the most promising models will be moved into a preclinical testing pipeline. All data from the work and the resulting models will be freely available to other scientists.
Alzforum (1/20) 
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New smart patch may benefit type 1 diabetes patients, study finds
A study in ACS Nano showed that a new smart patch developed by US and Chinese researchers can monitor blood glucose and deliver insulin automatically to type 1 diabetes patients, and it may also benefit patients with advanced type 2 diabetes. The mice with diabetes were able to maintain consistent insulin concentrations in their blood after being given the smart patch, researchers found.
United Press International (1/18) 
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Other News
Animal Health
CDC searches for more people infected by rat-borne virus
The CDC is expanding its search for people affected by Seoul virus, a form of hantavirus that circulates in wild and pet rats, beyond Wisconsin and Illinois to Alabama, Arkansas, Colorado, Indiana, Louisiana, Michigan, Minnesota, South Carolina, Tennessee and Utah. At least eight people in Wisconsin and Illinois who work in breeding facilities for pet rats were infected with the virus.
STAT (tiered subscription model) (1/24) 
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Policy News
Alaska law gives pets new standing in divorce proceedings
Pets are legally considered property, but a newly effective statute requires courts in Alaska to consider pets' well-being in deciding divorce cases and allows judges to assign joint custody. The new law permits courts to include pets under domestic violence protective orders and requires owners to pay for housing of pets seized in cruelty or neglect cases.
The Washington Post (tiered subscription model) (1/24) 
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FDA issues draft guidance for gene-edited animals
Draft guidance from the FDA would consider animals with intentionally altered genomes, as well as their offspring, to be separate new animal drugs subject to regulations as well as safety and efficacy review. The draft is open for public comment until April 19.
MIT Technology Review online (free registration) (1/20),  Nature (free content) (1/19),  GenomeWeb Daily News (free registration) (1/18) 
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Trump asks Collins to stay at NIH for now; Califf resigns from FDA
The Trump administration asked NIH Director Francis Collins to stay on, at least temporarily, according to an NIH spokeswoman. Robert Califf stepped down as FDA commissioner, and Stephen Ostroff, the agency's current commissioner for the Office of Foods and Veterinary Medicine, could fill the interim post.
The Washington Post (tiered subscription model) (1/19), (1/19),  The Scientist online (1/20) 
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Career official takes helm of CDC until new leadership is named
Physician Anne Schuchat, who served as principal deputy CDC director under former director Tom Frieden, will serve as acting director of the agency until new leadership is announced under President Donald Trump.
Food Safety News (1/23) 
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FBR News
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The Foundation for Biomedical Research (FBR) is the nation’s oldest and largest non-profit dedicated to improving human and animal health by promoting public understanding and support for biomedical research. Our mission is to educate people about the essential role animal research plays in the quest for medical advancements, treatments and cures for both people and animals.
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