Gut bacteria may play a role in Alzheimer's disease | Bacteria used to kill cancer tumors in mice | Study: Cancer patients at risk for BRCA mutation not always told about testing
February 13, 2017
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Gut bacteria may play a role in Alzheimer's disease
Researchers who took gut bacteria from mice with Alzheimer's disease and implanted it into healthy mice saw those animals develop more beta-amyloid plaques than mice that received bacteria from healthy animals, while mice without bacteria were substantially less prone to plaque buildup. The findings, discussed in Scientific Reports, suggest bacteria play a role in development of Alzheimer's, researcher Frida Fak Hallenius said.
The Atlanta Journal-Constitution (free content)/Cox Media Group (2/12) 
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Clinical News & Research
Bacteria used to kill cancer tumors in mice
Tumors have been destroyed in mice treated with the bacteria Salmonella typhimurium, according to findings published in Science Translational Medicine. The bacteria colonize in the tumors, killing them as they multiply, and also stimulate the body's immune system, which joins in to eradicate the tumors.
The Scientist online (2/8) 
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Study: Cancer patients at risk for BRCA mutation not always told about testing
A study published in the Journal of the American Medical Association found that nearly 81% of newly diagnosed breast cancer patients at high risk for a BRCA mutation wanted genetic testing, but only 39.6% received genetic counseling and 50.9% received a genetic test. Most said their doctor had not recommended testing, 13.7% said the test was too expensive and 10.7% said they did not want testing.
National Public Radio (2/7),  HealthDay News (2/7) 
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Industry Report
Radiotracer injection quality study launched by Lucerno
North Carolina-based Lucerno Dynamics has launched a trial involving more than 10,000 patients at as many as 12 participating centers across the US, using the company's Lara System as part of an assessment of PET/CT radiotracer injection process quality and capacity for quality improvement. Completion of the study will represent "an important step toward understanding what happens during a patient's uptake period and could help us improve the quantitative capabilities of PET/CT imaging," said co-principal investigator Dr. Terence Wong. (Raleigh, N.C.) (2/10) 
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Trial begins for Owlstone's breath-based cancer detection technology
A 1,400-patient clinical trial has been launched by UK medtech firm Owlstone Medical to assess the accuracy of its breath-based microchip Field Asymmetric Ion Mobility Spectrometer platform technology in detecting early-stage colorectal cancer. The study is being conducted in collaboration with the University Hospital Coventry, Warwickshire NHS Trust and the University of Warwick. (Boston) (2/7),  Business Weekly (U.K.) (2/7) 
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News from the Field
A "call to arms" on cancer drug prices
The rising cost of cancer drugs, which can total more than $100,000 annually per patient, is not sustainable, and prices should be cut by at least a third to half, according to a paper in the journal Cell that co-author Paul Workman of the Institute of Cancer Research said is a "call to arms." Academic researchers should drive drug development, focus on partnerships with smaller companies or nonprofits, and integrate drug price caps into negotiations with industry partners, the paper argues.
Reuters (2/9) 
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Health Policy
Hearing for CMS nominee set for this week
The Senate Finance committee will question Seema Verma, President Donald Trump's nominee for CMS administrator, in a hearing on Thursday, according to the panel. Verma worked with Vice President Mike Pence when he was governor of Indiana to design the state's Medicaid expansion plan.
The Hill (2/9) 
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Administration signals support for federal "right to try" measure
The White House has indicated support for a federal "right to try" law that would allow terminally ill patients greater access to experimental medications that haven't been approved by the FDA. Similar measures have been approved in 31 states.
The Wall Street Journal (tiered subscription model) (2/8) 
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Advancing Health Care
Exec offers suggestions to boost affordable, efficient rural health care
Rural health care providers can achieve efficient and affordable care by creating relationships with other organizations within the community, implementing cost-saving care innovations, and leveraging telehealth and interoperable health IT systems, writes Irv Lichtenwald, president and CEO of Medsphere Systems. Combining strategy and technology will allow rural hospitals "to move beyond survival and become catalysts for healthier communities," Lichtenwald writes.
HIT Consultant (2/8) 
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CTN webinar this Thursday: Quantitative Image Analysis -- The Tech Perspective
Advanced imaging techniques increasingly play a critical role in cancer care, for diagnosis, staging and response to therapy monitoring. The nuclear medicine technologist is key to obtaining accurate and repeatable images. Join Paul Galette and Adam Opanowski -- Thursday, Feb. 16, at 3 p.m. ET -- as they present the key role the nuclear medicine technologist plays in the process of quantitative image analysis. Register today!
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Review 25 abdominal MRI cases
ACNM and SNMMI have partnered to bring you the first-ever set of online MRI teaching modules as an introduction to interpreting MRI. This activity features a review of 25 Abdominal MRI Cases. 12.5 AMA PRA Category 1 Credits™ and 12.5 SAM Credits are available. Learn more and get started today.
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A small body of determined spirits fired by an unquenchable faith in their mission can alter the course of history.
Mahatma Gandhi,
social reformer and independence movement leader
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The news summaries appearing in SNMMI SmartBrief are based on original information from multiple internet sources and are produced by SmartBrief, Inc., an independent e-mail newsletter publisher. The items above are not selected or reviewed by SNMMI prior to publication. Questions and comments may be directed to SmartBrief at
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