An American College of Cardiology expert consensus decision pathway published in the Journal of the American College of Cardiology said SGLT2 inhibitors and GLP-1 receptor agonists can be used to reduce risks for major adverse cardiovascular events in patients with type 2 diabetes. "These therapies were initially developed to treat blood glucose in patients with diabetes and now have been shown to have important cardiovascular benefits," said Dr. Brendan Everett, co-chair of the writing committee.
A study in the International Journal of Colorectal Disease found that patients who were treated with metformin had a significantly lower risk of developing colorectal cancer, compared with those who were not treated with metformin or sulfonamide monotherapy. The findings, based on a systematic review of 17 studies with a total of 1,092,074 diabetes patients, also found that the use of metformin was tied to a significantly lower CRC risk among American and European patients.
Perfluoroalkyl substances, or PFAS, could be linked to obesity, endometriosis, polycystic ovary syndrome and other adverse health outcomes, according to a series paper published in The Lancet Diabetes & Endocrinology. Additionally, the researchers wrote that PFAS, bisphenols and certain pesticides may damage semen, while flame retardants and chemicals found in some pesticides could contribute to IQ loss and attention deficit hyperactivity disorder.
The ketogenic, modified Atkins and low glycemic index therapy diets were associated with similar reductions in seizures among children with drug-resistant epilepsy, a study in JAMA Pediatrics showed. Researcher Dr. Eric Kossoff said the low glycemic index and modified Atkins diets did not work as well as the keto diet, but the low glycemic index therapy had fewer side effects.
Taste changes were reported by 38% of patients with end-stage kidney disease, and were associated with certain gastrointestinal symptoms, such as nausea and vomiting, researchers reported in the Journal of Renal Nutrition. Patients who had taste changes were more likely to be malnourished.
A study published in Arthritis Care & Research found 56.3% of patients with systemic lupus erythematosus developed cachexia with loss of homeostatic control of protein and energy balance. The involuntary weight loss was permanent in 18% of patients studied.
The number of physicians affiliated with a health care system increased from 40% to 51% from 2016 to 2018, researchers reported in Health Affairs. Among primary care physicians the increase was from 38% to 49%.
The proposed 2021 Physician Fee Schedule for Medicare calls for making permanent some telehealth rules created for the novel coronavirus pandemic, along with workforce flexibilities such as allowing nurse practitioners, clinical nurse specialists, and other providers to supervise those performing diagnostic tests. The CMS said the provisions would help ensure "health care professionals can practice at the top of their professional training."
President Donald Trump on Thursday signed an executive order requiring the government to purchase essential drugs from companies in the US instead of those overseas. White House trade adviser Peter Navarro said the order also lifts some pharmaceutical manufacturing regulations and accelerates the review process for making some drug ingredients.
81st Scientific Sessions Call for Session Proposals
The American Diabetes Association's Scientific Sessions Meeting Planning Committee is soliciting high quality, innovative session proposals for the 81st Scientific Sessions. You must be an American Diabetes Association Professional Member to submit a proposal. The deadline for submitting a proposal is Friday, Aug. 14. Submit a Session Proposal!