Nut consumption may boost cognitive functioning in older adults | Amphetamine linked to higher psychosis risk in youths with ADHD | Prenatal, infant pesticide exposure tied to ASD risk
March 22, 2019
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Nut consumption may boost cognitive functioning in older adults
Researchers found that older adults who ate more than 10 grams of nuts and/or peanuts daily had a 40% lower likelihood of poor cognitive function, compared with non-eaters, even after accounting for body mass index, energy intake, lifestyle and demographics. The findings in The Journal of Nutrition, Health and Aging were based on 22 years of China Health and Nutrition Survey data from 4,822 individuals older than 55.
The Independent (London) (tiered subscription model) (3/21),  The Malay Mail (Malaysia)/Agence France-Presse/Relaxnews (3/21) 
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Clinical News & Research
Amphetamine linked to higher psychosis risk in youths with ADHD
Only about 1 in 660 children and young adults who received stimulants for attention-deficit/hyperactivity disorder developed psychosis, but those who were given amphetamine had twice the psychosis risk, compared with those who took methylphenidate, researchers reported in The New England Journal of Medicine. The findings also showed that amphetamine and methylphenidate prescriptions among youths with ADHD rose by nearly fourfold and 60%, respectively, between 2005 and 2014.
Reuters (3/20),  CNN (3/20) 
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Prenatal, infant pesticide exposure tied to ASD risk
Children whose mothers lived within 2,000 meters of areas highly sprayed with pesticides during pregnancy had 10% to 16% higher rates of autism spectrum disorder compared with those whose mothers lived farther from highly sprayed areas, researchers reported in The BMJ. Exposure during the first year of life was associated with 50% greater risk of ASD.
TIME online (3/20) 
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Propofol can help ease upsetting memories, study suggests
The anesthesia drug propofol may reduce the clarity of distressing memories after 24 hours have elapsed, a study published in Science Advances suggests. The drug could one day be useful in treating post-traumatic stress disorder, but only in a limited way, since older memories are less likely to change, researchers say.
New Scientist (free content) (3/20) 
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Industry Report
Biogen, Eisai end clinical trials for investigational Alzheimer's drug
Biogen and Eisai are discontinuing two late-stage trials evaluating aducanumab in treating Alzheimer's disease after an interim analysis from an independent monitoring committee showed the drug's unlikely benefit for Alzheimer's patients. Eisai has begun late-stage trials assessing the experimental Alzheimer's drug BAN2401.
STAT (tiered subscription model) (3/21),  Reuters (3/22) 
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FDA issues warning on higher mortality risk for myeloma drug
The FDA warned health professionals, cancer researchers and patients that the use of AbbVie's multiple myeloma drug Venclexta, or venetoclax, could lead to higher mortality risk, according to data from a late-stage trial evaluating the treatment. However, the warning does not cover use of the drug by patients already taking it for three approved indications.
Seeking Alpha (3/21) 
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News from the Field
Ask-A-Doc program shortens consult turnaround times
Data from Geisinger's Ask-A-Doc program, which included 22,000 physician consultations, showed it reduced the turnaround time between primary and specialty physicians to 6.5 hours, compared with traditional referrals that could take weeks to months. The program also reduced costs, mainly due to fewer emergency department and physician office visits.
Health Data Management (free registration) (3/21) 
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Health Policy
Gottlieb: Tighter scrutiny of EHRs needed amid reports of patient harm
Gottlieb: Tighter scrutiny of EHRs needed amid reports of patient harm
Gottlieb (Mark Wilson/Getty Images)
FDA Commissioner Scott Gottlieb has called for stricter scrutiny of EHR systems in light of reports of patient deaths, injuries and close calls related to the conversion from paper to electronic records. The 21st Century Cures Act prevents the FDA from overseeing EHRs as medical devices, and Gottlieb said companies have avoided adding functionality that could improve the systems because of concern the changes would bring them under FDA oversight.
Kaiser Health News/Fortune (3/21) 
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CMS: 95% of eligible providers join merit-based payment program
The CMS' 2017 Quality Payment Program Experience Report said 95% of eligible providers participated in the first year of the Merit-based Incentive Payment System, and 93% earned a positive payment adjustment. The agency said it is working with clinicians to reduce administrative burdens associated with participation.
Healthcare Dive (3/21) 
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Advancing Health Care
Study examines electronic prior authorization adoption in health care
Although electronic prior authorization was associated with an 80% higher dispense rate and faster turnaround times, adoption among health care providers is less than 50% of the market, according to data from health care software company CoverMyMeds. Researchers also found that combining electronic prior authorization with a real-time check of benefits at the point of prescribing led to a 20% increase in medication adherence.
Healthcare Dive (3/20) 
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Build tangible skills you can use immediately in your clinic
In addition to cutting-edge science and research you've come to expect each year, SNMMI's Annual Meeting will feature "Nuts and Bolts" sessions, giving you practical information you can use immediately to be the expert in your clinic. Sessions include: Nuts and Bolts: Using Lutetium-177 Dotatate; The Nuclear Medicine Report -- How to Get Paid with PAMA; Imaging and Therapy for Thyroid Cancer: the Theranostics Paradigm; and more! Register today.
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I had a running compiler and nobody would touch it because, they carefully told me, computers could only do arithmetic; they could not do programs.
Rear Adm. Grace Murray Hopper,
developer of the first compiler for a computer programming language

March is Women's History Month

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The news summaries appearing in SNMMI SmartBrief are based on original information from multiple internet sources and are produced by SmartBrief, Inc., an independent e-mail newsletter publisher. The items above are not selected or reviewed by SNMMI prior to publication. Questions and comments may be directed to SmartBrief at snmmi@smartbrief.com.
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