A small study published in the American Journal of Obstetrics and Gynecology found that pregnant women who had received either the Moderna or Pfizer/BioNTech vaccine in their third trimester had a strong immune response after vaccination, indicating that the vaccines protect pregnant women against COVID-19, and that a longer time between vaccination and delivery was linked to greater transfer of COVID-19 antibodies to the baby. The findings, based on data from 27 pregnant women and their babies, also showed that mothers who received a second dose of the two-dose vaccines prior to delivery were more likely to transfer COVID-19 antibodies to their infants.
A systematic review of international randomized control trials published in The Lancet shows both vaginal progesterone and intramuscular 17-hydroxyprogesterone caproate can reduce the risk of early preterm birth in singleton pregnancies in women at high risk due to a previous spontaneous preterm birth or short cervix. The risk reduction was greater in women with a short cervix.
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CDC Director Rochelle Walensky said the US needs to accelerate the pace of vaccination to combat emerging variants like B.1.1.7, which is now the predominant coronavirus variant in the US. The variant had been identified in 16,275 cases across 52 US jurisdictions as of Tuesday, with Florida, Michigan and Wisconsin having the most B.1.1.7-linked cases, according to CDC data.
Michigan, Florida, New Jersey, New York and Pennsylvania accounted for 44% of new COVID-19 cases in the US over the past week, though they are home to 22% of the national population, according to Johns Hopkins University. The report has prompted calls for the Biden administration to send extra COVID-19 vaccines to those areas and change its current policy of dividing the supply based on population.
The NIH has started a study that will examine some recipients' severe allergic reactions to COVID-19 vaccines developed by Pfizer/BioNTech and Moderna. The trial will enroll 3,400 adults, and it will examine possible predictors of reactions, including history of allergies and genetic predisposition.
Health records data from 236,379 patients who survived COVID-19 showed that 34% were diagnosed with a psychiatric or neurological disorder within six months, with anxiety and mood disorders the most common conditions. Dementia, stroke and other neurological disorders were less common but still significant, researchers reported in The Lancet Psychiatry.
Researchers found that preterm birth was associated with an increased risk of developing heart failure in adulthood. The findings in JAMA Pediatrics also showed that the risk was linked to younger gestational age and was highest among those born extremely prematurely.
American College of Radiology Breast Imaging Commission Chair Dr. Dana Smetherman said imaging facilities are not following US Preventive Services Task Force breast cancer screening recommendations because guidelines from breast cancer experts at the ACR, the Society of Breast Imaging, American Society of Breast Surgeons and American College of Obstetricians and Gynecologists recommend starting at age 40 rather than age 50 -- which saves more lives. "What this study is telling us is that the experts in breast cancer in the U.S. do not support these [USPSTF] recommendations," Smetherman said.
An artificial intelligence model improved identification of malignant breast tumors on ultrasound images, according to a study published in the Chinese Medical Journal. AI could spot cancer more quickly and also ease workloads of providers, researchers said.
Babies born at 26 weeks or earlier had spontaneous intestinal perforation if given a combination of antenatal steroids and prophylactic indomethacin, according to a study published in the Journal of Pediatrics. The retrospective study of infants in the Canadian Neonatal Network units also associated prophylactic indomethacin with lower chances of mortality.