January 15, 2021
Critical Care SmartBrief
Critical Care Update
A study in the journal Obesity found that patients with COVID-19 admitted to the intensive care unit, as well as those treated with mechanical ventilation, had a greater visceral fat area value, compared with patients hospitalized with COVID-19 not taken to the ICU or treated with ventilation. The findings were based on data from an analysis of six studies encompassing 560 COVID-19 patients.
Full Story: Healio (free registration)/Endocrine Today (1/13) 
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A study conducted by Mayo Clinic researchers found that antibody-rich convalescent plasma administered to hospitalized adult COVID-19 patients who did not need mechanical ventilation was associated with a lower mortality risk, compared with plasma transfusion with lower antibody concentrations. The findings, published in the New England Journal of Medicine, also showed that convalescent plasma did not alter mortality risk for patients with COVID-19 who were receiving mechanical ventilation.
Full Story: Center for Infectious Disease Research and Policy (1/13) 
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COVID-19 case data from May 31 through Dec. 12 showed pediatric incidence generally tracked adult rates in the US, according to CDC researchers writing in the Morbidity and Mortality Weekly Report. Overall, 2.5% of all children and adolescents with COVID-19 were hospitalized, 0.8% were admitted to the ICU and less than 0.1% died, researchers reported, while 16.6% of adults were hospitalized, 8.6% had ICU care and 5% died.
Full Story: Healio (free registration) (1/14) 
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Medicine in the News
Clinical leaders at five Arizona health systems want a meeting with Gov. Doug Ducey because the COVID-19 pandemic has strained their resources almost to the point of rationing. Ducey has said he is happy with current COVID-19 mitigation efforts, but the executives called for additional measures and said if triage is needed they will adopt those standards of care at the same time.
Full Story: The Arizona Republic (Phoenix) (tiered subscription model) (1/14),  KPNX-TV (Phoenix) (1/13) 
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An updated report by the CDC indicates that the total number of COVID-19 vaccines distributed as of Jan. 14 has reached 30,628,175 doses, while the number of first doses administered now stands at 11,148,991.
Full Story: Reuters (1/14) 
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Trends and Technology
A survey of parents with infants in a neonatal intensive care units found those with higher incomes and infants with more serious conditions were more likely to enroll in clinical trials, according to a study in JAMA Network Open. Parents who did not participate had less trust in medical research, but parental understanding of the study was not associated with differences in rates of enrollment.
Full Story: Contemporary Pediatrics (1/14) 
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Connect deeply with others. Our humanity is the one thing that we all have in common.
Melinda Gates,
philanthropist, advocate for women and girls
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