October 18, 2021
ASNC SmartBrief
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SPECT can foretell patient risk in HF, study finds
Researchers evaluated patients with heart failure with preserved ejection fraction and found that those who showed higher blood-flow defect levels on iodine-123 metaiodobenzylguanidine SPECT scan images were at an increased risk of dying from cardiac events, compared with those who had low blood-flow defect levels. "These results indicate that obtaining I-123 MIBG-SPECT analysis would provide additive prognostic value in patients with HFpEF," study authors wrote in JACC: Cardiovascular Imaging.
Full Story: AuntMinnie (free registration) (10/18) 
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Medical Focus
PET/MRI with gallium-68 PSMA-11 was found to be better at detecting recurrent prostate cancer than MRI alone, according to a study published in Translational Oncology. "Combined utility with PSMA PET/MRI is a powerful tool which can aid in not only the detection of disease, but also guide in treatment planning for prostate cancer patients," researchers said.
Full Story: AuntMinnie (free registration) (10/15) 
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A study in the journal Blood found [68] Ga-Pentixafor-PET/MRI, targeting the chemokine receptor CXCR4, showed a high level of accuracy in finding residual gastric mucosa-associated lymphoid tissue or MALT lymphoma. Researchers found it showed 97% accuracy in detecting MALT lymphoma in the stomach following H. pylori treatment.
Full Story: Medical Dialogues (10/17) 
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A study in a radiology journal found a Ga-68-labeled fibroblast activation protein inhibitor PET tracer -- Ga-68 FAPI-46 -- may help identify metastatic and primary tumors on hybrid PET/MRI imaging in women with advanced breast cancer. The retrospectively analysis included 18 patients with large or locally advanced breast tumors.
Full Story: AuntMinnie (free registration) (10/14) 
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A study funded by Eli Lilly and Company and published in the journal Diabetes, Obesity and Metabolism found that patients with type 2 diabetes who took 10 mg or 15 mg of tirzepatide for 26 weeks experienced a decrease in biomarkers tied to chitinase-3 like-protein-1 and leptin, compared with those treated with either dulaglutide or placebo. Patients who took 15 mg of tirzepatide also had a reduction in intercellular adhesion molecule 1 levels compared with those who took placebo or dulaglutide, as well as reduction in high-sensitivity C-reactive protein levels compared with those who took placebo.
Full Story: Medical Dialogues (10/12) 
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Regulatory & Policy
How to reduce repeat ED visits
Norwalk Hospital significantly reduced the number of repeat visits to its emergency department after staff began holding weekly meetings for case reviews, developed tailored care plans and implemented a system to connect repeat patients with community resources, according to clinical social worker Eileen Kardos. Meetings are brief and target a specific patient population, social determinants of health are discussed, teams of nursing and social work students from a local university are involved, and handoffs to community resources are "warm," Kardos says.
Full Story: MedPage Today (free registration) (10/14) 
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ASNC releases cardiac PET lectures today
Registrants for ASNC's Cardiac PET Advanced Virtual Workshop will soon receive access to five lectures pre-recorded by experts to set the stage for the Oct. 30-31 program. The lectures include "Addressing Incidental Findings on the CT Scan in a PET/CT Study" by Timothy M. Bateman, MD, MASNC; "Interpretation of Incidental Cardiac and Non-Cardiac Findings on SPECT and PET-CT" by Andrew Homb, MD; "Cardiac Metabolism Imaging" by Rob S.B. Beanlands, MD, MASNC; "Metabolic Imaging" by Panithaya Chareonthaitawee, MD; and "Technical Aspects in Hot Spot Imaging" by Chi Liu, PhD. If you have attended a prior ASNC workshop or your cardiac PET lab has been active for at least one year, attend the Advanced program to learn how to handle challenging perfusion and non-perfusion PET cases. REGISTER NOW.
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Committees shape ASNC's educational and quality programs and fuel federal and state advocacy efforts that impact your practice. As a committee volunteer, you'll be advancing ASNC's mission while also expanding your professional network, demonstrating your talents, creating new career opportunities, and growing the nuclear cardiology field. Joining a committee is the best way to optimize the value of your ASNC membership - plus volunteers enjoy new challenges and forge friendships with peers from around the world. Submit your interest statement by Oct. 25. VOLUNTEER NOW.
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