Counties with high and medium opioid prescribing rates had 1.6 times and 1.4 times higher prevalence of babies with gastroschisis, respectively, compared with counties with low opioid prescribing rates, CDC researchers reported in the agency's Morbidity and Mortality Weekly Report. The findings, based on data from 2006 to 2015 across 20 states, also showed a 30% increase in infant gastroschisis rates from 2006 to 2012, and while babies born to mothers younger than 20 remained most likely to develop gastroschisis, the greatest gain in prevalence was found among those born to older mothers.

A new genetic risk score known as T1DGRS2 appears twice as efficient in predicting risk of developing type 1 diabetes compared with current methods, according to a study in Diabetes Care, and it could be used to predict risk in babies. Researchers analyzed gene interactions and genetic variation in more than 6,500 patients with type 1 diabetes and found that the new test was more accurate and was able to help distinguish between type 1 and type 2 diabetes.

Researchers found that 69.9% of children younger than 2 who were given antibiotics in emergency departments for bronchiolitis didn't have any documented concomitant bacterial infection, with penicillins and macrolides being the most commonly prescribed antibiotics. The findings in the Journal of the Pediatric Infectious Diseases Society should prompt the implementation of quality improvement interventions, especially in nonpediatric and nonteaching hospitals, researchers wrote.

A study in the Journal of Diabetes Investigation revealed that interdependent tendencies may negatively affect diabetes self-care among type 2 diabetes patients. Japanese researchers surveyed 161 adult diabetes patients, mean age of 65.1, and found that age and emotional support were positively associated with diabetes self-care among men who were younger than 68 years old, while interdependent tendency was negatively correlated with diabetes self-care among women in the same age group.

Nearly 43.4% of adolescents ages 13 to 17 were given complete human papillomavirus vaccination, but only 15.8% and about 34.8% had received all recommended HPV vaccine doses by ages 13 and 15, respectively, according to a study in the Journal of Infectious Diseases. Researchers also found higher odds of up-to-date HPV vaccination at ages 13 and 15 among those who had one health provider, compared with those with two or more providers.

Almost a third of 104 pediatric renal transplant patients at Boston Children's Hospital had a genetic mutation tied to kidney disease, based on results from whole-exome sequencing. The findings were reported in the Journal of the American Society of Nephrology.

Researchers used a common wearable movement sensor to measure physiological responses of 63 children ages 3 to 7 to a 90-second mood induction task with the goal of detecting internalizing disorders, including depression and anxiety. The study, published in PLOS ONE, found that performing a machine learning algorithm-based analysis of just 20 seconds of movement data had an 81% accuracy rate in identifying children with internalizing disorders.

The CMS unveiled its proposed notice of benefit and payment standards for Affordable Care Act plans for the 2020 coverage year and it includes proposals to lower ACA user fees, allow insurers to adopt midyear prescription formulary changes and increase the annual cost-sharing limit to $8,200 for self-only coverage and $16,400 for family coverage. The agency also asked for comments on how it might address the practice of silver-loading -- concentration of premium increases in silver plans -- and indicated support for a legislative fix enabling cost-sharing reduction payments to resume.

The FDA has issued a letter to health care providers alerting them of an investigation into paclitaxel-coated and paclitaxel-eluting devices designed for treating peripheral artery disease in the legs after a review in the Journal of the American Heart Association linked use of these devices with increased all-cause mortality risk. Spokespeople for Boston Scientific and Medtronic both noted that the meta-analysis did not consider patient-level data and maintained that the companies' devices were safe.

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