Mobidiag secured a four-year loan worth about $28 million from the European Investment Bank. The company said it will use the money for validation and commercialization of new molecular diagnostic tests running on the firm's Amplidiag and Novodiag platforms.
Roche Diagnostics has commercially released its Cobas MTB-RIF/INH test for antibiotic resistance detection in tuberculosis DNA. The product comes as part of the mycobacterium test menu that runs on the company's automated Cobas 6800/8800 systems.
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Researchers who used PET found that individuals with post-traumatic stress disorder and suicidal thoughts had significantly elevated metabotropic glutamatergic receptor 5 availability across five key brain regions and had a positive correlation between total Profile of Mood States scores and mGluR5 availability, but the association wasn't observed among those with PTSD who did not have suicidal thoughts. The findings, published in the Proceedings of the National Academy of Sciences, suggest that mGluR5 downregulation might curb PTSD symptomology, but more studies are needed, said researcher Dr. Irina Esterlis.
A Portuguese study in The Journal of Clinical Endocrinology & Metabolism showed no association between prediabetes and worsening kidney function or incident albuminuria in the short term, with similar rates seen among those with impaired fasting glucose and normoglycemia. Findings were based on an analysis of data from the SPRINT trial involving 9,361 participants without diabetes at baseline, mean age of 68.
People with diabetes may be at an increased risk of cancer metastasis due to elevated blood glucose levels that could lead to glycation, which in turn "promotes the rate of metastasizing," lead study author Young Joon Suh wrote in the journal Integrative Biology. Researchers examined how breast cancer tumor cells survived in environments with varying glycation levels and found that cells in environments with high glycation had increased motility and were able to move farther away from the original site.
The FDA has given Illumina spinout Grail breakthrough device designation for its early detection test that can spot multiple cancer types from a single blood sample. The sequencing test is being evaluated in a 37-site US study involving around 100,000 women.
Chembio Diagnostic Systems' point-of-care test for dengue was granted approval by Brazilian regulators. The DPP Dengue System requires a drop of blood from the fingertip and can generate results within 15 minutes.
Dr. Alec Saitman will provide insight into an auto-data review program developed by Providence Regional Laboratories. This program has unique advantage of providing dynamic rule flags against patient samples using calibrator averages of important data elements. May 29, 2019