October 27, 2021
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Top Story
The CDC said in updated guidelines that certain people with weakened immune systems who have received three doses of an mRNA COVID-19 vaccine may be candidates for a fourth dose at least six months after receiving the third shot. The statement applies to moderately to severely immunocompromised adults, including those with untreated or advanced HIV, people who are undergoing treatment for tumors or blood cancers, those who have received certain transplants, and patients who take high doses of immunosuppressants.
Full Story: CNN (10/27) 
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PGDprime: easily address FDA Guidance.
With the PGDprime® test it's easy to manage your platelet inventory. No centrifugation, no precision pipetting and increased availability with 7 Day dating. Most users complete testing in <1 hour per day. And train on-line with our video training program - over 1600 people already have. Learn more.
Science & Health
New guidance from the American Society of Hematology on hematopoietic stem cell transplants for patients with sickle cell disease was published in the journal Blood Advances. The recommendations include performing transplants earlier in life for patients where transplant is indicated and a matched donor is available.
Full Story: Healio (free registration) (10/25) 
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CDC: US administers over 415M COVID-19 vaccine doses
(Michael M. Santiago/Getty Images)
As of Tuesday, the CDC said over 415 million COVID-19 vaccine doses have been administered in the US -- and almost 190.8 million Americans are now fully vaccinated. The agency also said that an estimated 13.8 million people have gotten a booster dose of the COVID-19 vaccines from either Pfizer/BioNTech, Moderna or Johnson & Johnson.
Full Story: Reuters (10/26) 
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Emerging Trends
Sickle Cell Disease Association of America CEO Beverley Francis-Gibson enlisted Forma Therapeutics to develop a clinical trial locator that will soon be available as a smartphone app. Users can find clinical trials by location and type of trial, as well as learn about the different types of clinical trials.
Full Story: The Baltimore Sun (tiered subscription model) (10/26) 
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Government & Regulatory
An FDA advisory panel voted on Tuesday to recommend emergency use authorization of a reduced dose of Pfizer/BioNTech's COVID-19 vaccine for children ages 5 to 11. The FDA could make a decision within days, and the CDC's vaccination advisers are scheduled to meet on Nov. 2 to discuss vaccination of younger children.
Full Story: National Public Radio (10/26),  HealthDay News (10/26) 
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A request for emergency use authorization has been submitted by Applied DNA Sciences to the FDA for its Linea SARS-CoV-2 Mutation Panel.
Full Story: Seeking Alpha (free registration) (10/25) 
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Association News
Complimentary registration is available to a Nov. 4 Science & Innovation Forum presented by Cerus Corporation that will explore the implementation of pathogen-reduced platelets. In this program, transfusion safety officers (TSOs) from a leading pediatric institution and a large hospital network will share their perspectives on the role that pathogen-reduced platelets play in meeting hospital demands. The program will take place at 2 p.m. ET on Thursday, Nov. 4. Registration is complimentary but required to attend.
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