CDC: Immunocompromised may need 4th COVID-19 vaccine shot | Group issues guidance on HSCT for sickle cell disease | CDC: US administers over 415M COVID-19 vaccine doses
October 27, 2021
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News for the transfusion medicine and biotherapies community
The CDC said in updated guidelines that certain people with weakened immune systems who have received three doses of an mRNA COVID-19 vaccine may be candidates for a fourth dose at least six months after receiving the third shot. The statement applies to moderately to severely immunocompromised adults, including those with untreated or advanced HIV, people who are undergoing treatment for tumors or blood cancers, those who have received certain transplants, and patients who take high doses of immunosuppressants.
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New guidance from the American Society of Hematology on hematopoietic stem cell transplants for patients with sickle cell disease was published in the journal Blood Advances. The recommendations include performing transplants earlier in life for patients where transplant is indicated and a matched donor is available.
As of Tuesday, the CDC said over 415 million COVID-19 vaccine doses have been administered in the US -- and almost 190.8 million Americans are now fully vaccinated. The agency also said that an estimated 13.8 million people have gotten a booster dose of the COVID-19 vaccines from either Pfizer/BioNTech, Moderna or Johnson & Johnson.
Sickle Cell Disease Association of America CEO Beverley Francis-Gibson enlisted Forma Therapeutics to develop a clinical trial locator that will soon be available as a smartphone app. Users can find clinical trials by location and type of trial, as well as learn about the different types of clinical trials.
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An FDA advisory panel voted on Tuesday to recommend emergency use authorization of a reduced dose of Pfizer/BioNTech's COVID-19 vaccine for children ages 5 to 11. The FDA could make a decision within days, and the CDC's vaccination advisers are scheduled to meet on Nov. 2 to discuss vaccination of younger children.
Complimentary registration is available to a Nov. 4 Science & Innovation Forum presented by Cerus Corporation that will explore the implementation of pathogen-reduced platelets. In this program, transfusion safety officers (TSOs) from a leading pediatric institution and a large hospital network will share their perspectives on the role that pathogen-reduced platelets play in meeting hospital demands. The program will take place at 2 p.m. ET on Thursday, Nov. 4. Registration is complimentary but required to attend.
