Surgeon in groundbreaking transplant is remembered | USPSTF advises hepatitis C screening for baby boomers | Method distinguishes potentially cancerous cells from healthy cells
November 27, 2012
AABB SmartBrief
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Surgeon in groundbreaking transplant is remembered
Dr. Joseph E. Murray, who in 1954 conducted the first successful transplant of a human organ, has died of complications after a stroke. Murray's pioneering kidney transplant involved 23-year-old twins, and he later developed methods used in tens of thousands of organ transplants. The New York Times (tiered subscription model) (11/27)
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Hemo bioscience has received FDA clearance for its complement coated control cells. Hemo bioscience C3 Control Cells can be used as a control to confirm the efficacy of the AHG reagent used during Direct and Indirect Anti-Globulin tests. For details regarding pricing, manufacturing schedule, and distribution channels email us or call 866-332-2835.
Science & Health
USPSTF advises hepatitis C screening for baby boomers
The U.S. Preventive Services Task Force on Monday in a draft recommendation advised primary care physicians to consider hepatitis C screening for adults born between 1945 and 1965, and it said those with a history of IV drug use or blood transfusions prior to 1992 should be tested. The recommendations were an update to the group's 2004 statement and urge screening for all high-risk adults. Reuters (11/26), HealthDay News (11/26)
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Method distinguishes potentially cancerous cells from healthy cells
Researchers in Japan have developed a method to differentiate potentially cancerous cells from a colony of heart muscle cells derived from embryonic stem cells and human induced pluripotent stem cells. The technique involves eliminating glucose from a culture medium while putting in lactate, according to a study published in Cell Stem Cell. The method could help boost the safety of the cells for clinical uses, a researcher said. The Asahi Shimbun (Japan) (11/21)
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Preclinical studies uncover promise of mRNA flu vaccine
Researchers in Germany have found that an H1N1 vaccine based on synthetic messenger RNA provided immunity in animal studies. Unlike the standard protein-based vaccine, the mRNA formulation can be mass-produced in eight weeks or less, does not need refrigeration and could be used in people who are allergic to the chicken-egg protein ovalbumin. More work is needed, but the researchers are hopeful the mRNA-based influenza vaccine may help protect people. blog (11/26)
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Researchers to test treatments for Chagas' disease
University of Georgia researcher Rick Tarleton, who is working on a vaccine for Chagas' disease, will collaborate with researchers at the Texas Biomedical Institute on animal tests of three treatments against the disease, which can be very difficult to detect. "The major problem in terms of drug treatment for Chagas' disease is that it is virtually impossible to determine if the treatment is effective," Tarleton said. Athens Banner-Herald (Ga.) (11/25)
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Need Help Applying for the NBF Grant?
AABB has added a FREE audioconference for November 28 titled How to Get That NBF Grant! This session will discuss the grant application process, common application mistakes, and factors the review committee considers when looking over proposals. All early-career researchers are encouraged to register whether they want to apply for a grant in 2013 or beyond.
Emerging Trends
10% of Americans have coverage through ACOs
Accountable care organizations now cover approximately 30 million Americans, or 10% of the population, according to a new study by Oliver Wyman. ACOs now cover 2.4 million Medicare patients, 15 million non-Medicare patients in Medicare ACOs and between 8 million and 14 million non-Medicare patients in non-Medicare ACOs. (11/26)
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Experts find obstacles to ACO development
Researchers at the Robert Wood Johnson Medical School in New Jersey who are developing an accountable care organization have reported on a three-part approach to establishment and identified six major barriers that affect the process. The issues include conceptual, cultural, regulatory and financial barriers, researchers wrote in Health Affairs. News (11/26)
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Industry News & Practice
Data show results of Ontario hospital's blood conservation efforts
The Peterborough Regional Health Centre in Ontario, Canada, said it is seeing positive results from its blood-conservation program, with the percentage of patients requiring transfusions at the center below the rate for the province. For 2011-12, 4.8% of people who had knee and hip procedures needed a blood transfusion, compared with the provincial figures of 10.1% for knee operations and 12.8% for hip surgeries. Twenty-five Ontario hospitals have blood conservation programs. (Ontario) (11/26)
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Mass. organ transport device firm obtains $36 million
TransMedics has secured $36 million in a round of equity financing from 15 backers. The Andover, Mass.-based company is the maker of the Organ Care System, a portable blood perfusion device designed to ensure that organs for transplantation are preserved while in transit from donor to recipient. American City Business Journals/Boston/BBJ Morning Buzz blog (11/27)
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Foundation and VA to seek cause of multiple myeloma
The Multiple Myeloma Research Foundation announced plans to work with the Department of Veterans Affairs to identify the causes of multiple myeloma. Researchers will analyze patients' tissue samples to learn how molecular and genetic profiles affect how the disease develops in particular patients and how they respond to treatments. GenomeWeb Daily News (free registration) (11/26)
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Government & Regulatory
FDA seeks comments on appropriate uses of custom device exemption
The FDA is asking for "information on and examples of appropriate uses" of the custom medical device exemption. In its notice, the agency encourages all stakeholders, including patients, physicians and manufacturers, to submit comments. (Boston) (11/23)
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Association News
Audioconference on applying for NBF grants to be held tomorrow
The audioconference "How to Get That NBF Grant!" will take place tomorrow, Nov. 28. This free session will review the grant application and scoring processes and provide tips to potential applicants. Led by NBF Grants Review Committee Chair James Zimring, M.D., Ph.D., this event is geared toward early-career researchers. Learn more.
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Who's Hiring?
Position TitleCompany NameLocation
West Coast Account ManagerMacopharma USAUS - Nationwide
Director, LaboratorySan Diego Blood BankUS - CA - San Diego
Director, Patient Blood ManagementAABBUS - MD - Bethesda
Help Desk SpecialistAABBUS - MD
Click here to view more job listings.
Every path hath a puddle."
-- George Herbert,
Welsh-British poet, orator and priest
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