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January 21, 2013
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News for nuclear medicine and molecular imaging professionals
The news summaries appearing in SNMMI SmartBrief are based on original information from multiple internet sources and are produced by SmartBrief, Inc., an independent e-mail newsletter publisher. The items below are not selected or reviewed by SNMMI prior to publication. Questions and comments may be directed to SmartBrief at

  Top Story 
  • Dedicated cardiac camera reduces radiation dose, acquisition time
    Researchers have developed a dedicated SPECT/MPI cardiac camera that has the potential to reduce imaging acquisition time and radiation dose, according to findings from a simulation study published in the Journal of Nuclear Medicine. Researchers, using reframed list-mode raw data, found that 1 million counts yielded images comparable to 8 million counts. The study involved 79 consecutive patients referred for a rest-stress MPI. Researchers are calling for similar simulation trials to test the feasibility of other dedicated cardiac modalities. (1/18) LinkedInFacebookTwitterEmail this Story
The MEDRAD™ Intego™ is making personalized PET practical.
Clinicians are able to set weight-based dosing formulas to determine and administer an accurate, personalized dose for each unique patient. Precise delivery and dose-on-demand capabilities enable lower patient dosing, leading to better patient care. To learn more, click here.
  Clinical News & Research 
  • Study links early amyloid buildup to risk of Alzheimer's disease
    Greater buildup of beta amyloid in the brain as measured through 18F-florbetaben PET imaging correlated with declining cognitive capability in older patients with mild impairment, according to a study in Alzheimer's Research and Therapy. Based on previous PiB-based studies, researchers said the current findings indicate beta amyloid accumulation in patients with higher florbetaben (FBB) absorption could lead to symptoms of Alzheimer's disease in five to seven years. "Moreover, the use of FBB may prove useful in the early differential diagnosis of mild cognitive impairment ... potentially aiding early therapeutic interventions as well as helping to predict prognosis," according to researchers. MedPage Today (free registration) (1/18) LinkedInFacebookTwitterEmail this Story
  • Study to test solanezumab's potential in preventing Alzheimer's
    Dr. Reisa Sperling, director of the Alzheimer's disease center at Brigham and Women's Hospital in Boston, will be heading a study that will test an experimental drug from Eli Lilly & Co. called solanezumab. The study, to include 1,000 people with plaque buildup but no signs of dementia, will test whether the drug can prevent the development of Alzheimer's when administered before symptoms manifest. Researchers are also paying close attention to whether the drug can at least hinder the speed of cognitive degeneration. The Washington Times/The Associated Press (1/18) LinkedInFacebookTwitterEmail this Story
  Industry Report 
  • GE reports promising results for its flutemetamol training initiative
    GE Healthcare reported that its electronic training program designed to improve the reading of results from PET imaging with its 18F-flutemetamol tracer yielded good results for inexperienced readers. The readers showed 94% sensitivity, 92% specificity, 87% positive predictive value and 96% negative predictive value in reading the images, company representatives said at a meeting on human amyloid visualization. (free registration) (1/18) LinkedInFacebookTwitterEmail this Story
  News from the Field 
  • Hospital implements measures to reduce patients' radiation exposure
    Allegheny General Hospital in Pittsburgh has initiated a program to reduce patients' radiation exposure during a common heart scan. The hospital said patients undergoing the test are now receiving just 25% of the radiation they would have been exposed to two to three years ago. Dr. Indu Poornima, medical director of nuclear cardiology at the hospital, said the reduction in radiation exposure did not negatively affect findings. American City Business Journals/Pittsburgh (1/18) LinkedInFacebookTwitterEmail this Story
  International Developments 
  Health Policy 
  • NIH director: Sequestration would devastate medical research
    The NIH's 27 institutes and centers face disruptive cutbacks if Congress does not act by March 1 to reverse automatic budget cuts. A slowdown in NIH funding since 2004, along with inflation, has already reduced the agency's purchasing power and left it unable to fund promising research, says Director Dr. Francis Collins. Moreover, NIH funds flow across the country, and cutbacks would mean nationwide job losses, Collins said. Politico (Washington, D.C.) (1/16) LinkedInFacebookTwitterEmail this Story
  Advancing Health Care 
  • Report: Drugmakers need new ways to fill clinical trials
    While about 89% of clinical trials meet their enrollment goals, 48% of trial sites miss enrollment and timeline goals, according to the Tufts Center for the Study of Drug Development. About 90% of drugmakers and research organizations use conventional methods such as physician referrals and mass media advertising to enroll participants, and only about 14% use social media, online data mining and EHRs to recruit participants. "The emergence of open innovation models, where scientists worldwide openly share knowledge, and novel partnerships and alliances hold significant promise to transform the nature, pace, and cost of new drug development," said Kenneth Kaitin, the center's director. blog (1/15) , PharmaTimes (U.K.) (1/17) LinkedInFacebookTwitterEmail this Story
  From SNMMI 
  • SNMMI joins Choosing Wisely
    What tests and procedures should patients and physicians be talking about in nuclear medicine and molecular imaging? Find out Feb. 21 when SNMMI announces its "Five Things Physicians and Patients Should Question" as part of the ABIM Foundation's Choosing Wisely campaign. LinkedInFacebookTwitterEmail this Story
  • New self-assessment modules (SAMs) available!
    Take advantage of new journal SAMs and earn credit before the end of the year! Popular SAMs include "Bringing Physiology into PET of the Liver," "Imaging of Multiple Myeloma and Related Plasma Cell Dyscrasias," "Modern Nuclear Imaging for Paragangliomas: Beyond SPECT" and "Effectiveness and Safety of FDG-PET in the Evaluation of Dementia." Get started today. LinkedInFacebookTwitterEmail this Story
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