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March 21, 2013
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News for nuclear medicine and molecular imaging professionals
The news summaries appearing in SNMMI SmartBrief are based on original information from multiple internet sources and are produced by SmartBrief, Inc., an independent e-mail newsletter publisher. The items below are not selected or reviewed by SNMMI prior to publication. Questions and comments may be directed to SmartBrief at

  Top Story 
  • Preclinical phase of Alzheimer's may last more than 20 years
    It takes 17 years for amyloid plaque accumulation to reach positive-test levels, as determined through PET imaging with carbon-11-labeled Pittsburgh compound B, and this indicates the preclinical phase of Alzheimer's disease may be lengthy, according to a study published in The Lancet. The study also found that atrophy of the hippocampus takes more than four years and that it takes 3.3 years of declining memory before patients are given a score of 1 in the standard rating for dementia. "Results from this study show, for what is to our knowledge the first time, an association between the rates of beta-amyloid deposition and memory decline in patients with AD, in whom faster deposition was significantly associated with faster memory decline," researchers said. (3/20) LinkedInFacebookTwitterEmail this Story
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  Clinical News & Research 
  • SPECT with DaTscan may boost differential diagnosis of dementia
    SPECT imaging using the radioactive iodine-based tracer DaTscan helped differentiate cases of Lewy body dementia and non-amnestic mild cognitive impairment from Alzheimer's disease and amnestic MCI, according to findings presented at a neurology meeting. DaTscan was approved last year as an imaging agent for the differentiation of Parkinson's disease from essential tremor. MedPage Today (free registration) (3/19) LinkedInFacebookTwitterEmail this Story
  Industry Report 
  • Lantheus enters isotope supply deal with IRE
    Belgium's Institute for Radioelements agreed to a five-year deal to provide Lantheus Medical Imaging with molybdenum-99. The supplied isotope will be used in Lantheus' TechneLite technetium-99 generators. Lantheus said the IRE is in the process of modifying its isotope production method to be able to use low-enriched uranium. (free registration) (3/20) LinkedInFacebookTwitterEmail this Story
  News from the Field 
  • Researchers, advocates say Alzheimer's funding is inadequate
    Alzheimer's disease has become the sixth-leading cause of death in the U.S., while death rates related to stroke, HIV/AIDS and breast cancer have declined. The Alzheimer's Association, doctors and researchers are calling for increased funding to find effective treatments and cures. Funding for NIH research into Alzheimer's was expected to increase this year, but levels are uncertain in light of sequestration and many meritorious grant applications have gone unfunded, says Mayo Clinic neurology professor Dr. David Knopman. Bloomberg (3/19) , Yahoo/The Associated Press (3/19) LinkedInFacebookTwitterEmail this Story
  International Developments 
  • Canada's budget deficit set to increase thanks to nuclear liability
    Canada's budget deficit for the current fiscal year is expected to be $2.3 billion higher than predicted, owing to Atomic Energy of Canada Ltd.'s higher liability estimate regarding the Chalk River research reactor. The nuclear agency said it is increasing its estimate from around $3.5 billion to more than $5.8 billion. Reuters (3/20) LinkedInFacebookTwitterEmail this Story
  Health Policy 
  • Prompt release of FDA guidance on mHealth urged at hearing
    The FDA should move promptly to release its final guidance on how it intends to regulate mobile health applications to provide clarity on the issue, industry experts said during the first of three hearings being conducted this week by the House Committee on Energy & Commerce. One expert also argued that imposing the 2.3% medical device tax on mHealth apps could stymie innovation. Clinical Innovation + Technology online (3/19) LinkedInFacebookTwitterEmail this Story
  • Some states decline to enforce ACA insurer rules
    Florida, Missouri, Oklahoma and Wyoming are among the states that will not enforce Affordable Care Act regulations regarding insurers, such as requiring insurers to accept all applicants and forbidding them from charging more based on gender. HHS has few state resources and little experience enforcing health insurance rules, experts say. Kaiser Health News/Capsules blog (3/19) LinkedInFacebookTwitterEmail this Story
  Advancing Health Care 
  • HHS picks Alzheimer's project for 2013 innovation award
    HHS has selected the Connecting to Combat Alzheimer’s program as the winner of the agency's third annual innovation award. The project, which links NIH-funded Alzheimer’s disease research facilities with caregivers, aging services and patients, has boosted the number of prospective research participants for clinical trials by 25%. Government Health IT online (3/19) LinkedInFacebookTwitterEmail this Story
  From SNMMI 
  • SNMMI 2013 Annual Meeting early-bird registration ends Thursday, April 11
    This year's SNMMI Annual Meeting — June 8-12 in Vancouver, British Columbia — features a wide range of cutting-edge scientific and CE sessions focused on the latest nuclear and molecular imaging research. Don't miss more than 100 CE sessions, 1,300+ scientific posters, nuclear medicine review course, CT case review sessions and student technologist registry review. Early-bird registration ends April 11. Register today! LinkedInFacebookTwitterEmail this Story
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