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February 15, 2013
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The news summaries appearing in BIO SmartBrief are based on original information from news organizations and are produced by SmartBrief, Inc., an independent e-mail newsletter publisher. The information is not compiled or summarized by BIO. Questions and comments should be directed to SmartBrief at bio@smartbrief.com.

  Today's Top Story 
  • Creating therapies with macrocycles could spur biologics development
    Comparatively few biologic drugs are making it to the market, and many of those are for rare diseases, writes Nick Terrett, chief science officer at Ensemble Therapeutics. Part of the reason is the difficulty of developing biologic drugs, but the industry could use a paradigm shift in how it develops drugs, Terrett writes. Combining small molecules and biologics could create a new therapy option, the macrocycle, he writes. Xconomy/Boston (2/14) LinkedInFacebookTwitterEmail this Story
  Health Care & Policy 
  • Janssen-Pharmacyclics lymphoma drug gets breakthrough status
    The FDA granted breakthrough therapy status to Janssen Biotech and Pharmacyclics' ibrutinib, a Bruton's tyrosine kinase inhibitor, as a treatment for relapsed or refractory mantle cell lymphoma and Waldenström's macroglobulinemia. The companies plan to submit the drug for approval for mantle cell lymphoma in 2013. PharmaTimes (U.K.) (2/14) LinkedInFacebookTwitterEmail this Story
  • Team in Japan clears hurdle on way to trial of iPS cells
    An ethics panel at the Institute for Biomedical Research and Innovation in Japan has given the green light for a clinical trial of induced pluripotent stem cells in the treatment of age-related macular degeneration. If Japan's Health Ministry approves the six-patient trial, it could begin this fiscal year. The Japan Daily Press (2/14) LinkedInFacebookTwitterEmail this Story
  Company & Financial News 
  Food & Agriculture 
  • Mexico's international grain research center wins $25M grant
    The Carlos Slim Foundation awarded the International Corn and Wheat Improvement Center in Mexico a $25 million grant for new facilities, including a greenhouse and laboratory installations. The research center, also backed by the Bill and Melinda Gates Foundation, develops corn and wheat that can tolerate drought, cold and pests. The center also is researching biotech corn. Fox Business/Dow Jones Newswires (2/13) LinkedInFacebookTwitterEmail this Story
  Industrial & Environmental 
  • Canadian cellulosic ethanol producer lands deal to sell lignin
    Canada-based Lignol Innovations has signed a deal to supply a European thermoplastics maker with purified lignin, a byproduct of cellulosic ethanol production. "When producing next-generation biofuels from renewable, nonfood feedstocks like wood chips, roughly 25% of the output is lignin," said Ross MacLachlan, president and CEO of Lignol Energy. The lignin can be sold for its calorific value or as a replacement for petroleum-based products, he said. EthanolProducer.com (2/13) LinkedInFacebookTwitterEmail this Story
  News from BIO 
  • BIOtechNOW
    BIOtechNOW is the first in a number of new products from BIO intended to enhance our communications with the biotech community -- not only with our members, but with other stakeholders as well. This e-newsletter, combined with its website, serves as our flagship in that effort. BIOtechNOW will offer original content that emphasizes the business needs of the industry; highlight BIO's advocacy efforts; and provide a portal to all BIO activities and events. Most importantly, it will spotlight for those outside the industry the value of biotechnology. Sign up for the e-newsletter. LinkedInFacebookTwitterEmail this Story
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  SmartQuote 
If you want to live a happy life, tie it to a goal. Not to people or things."
--Albert Einstein,
German-born theoretical physicist


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