Brain scans suggest link between brain injury, amyloid buildup | Study shows varied colorectal cancer rates worldwide | Peptide-based drug might be an alternative to opioids
 
February 4, 2016
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Brain scans suggest link between brain injury, amyloid buildup
A small study in the journal Neurology found that a traumatic brain injury may cause a buildup of amyloid plaques, which are often seen in the brains of patients with Alzheimer's disease. Researchers found that plaque buildup after head trauma was formed in the posterior cingulate cortex, an area also affected in Alzheimer's, as well as the cerebellum, the brain region in charge of motor control. Findings, based on participants who underwent PET, MRI and diffusion tensor imaging, also show that amyloid buildup correlated with levels of white matter damage. HealthDay News (2/3)
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Clinical News & Research
Study shows varied colorectal cancer rates worldwide
A study of data from the GLOBOCAN database showed incidence and mortality rates for colorectal cancer vary by a country's level of development. The study found CRC rates and mortality are increasing in many low-income and middle-income countries but stabilizing or decreasing in countries that are more highly developed. PhysiciansBriefing.com/HealthDay News (2/2)
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Peptide-based drug might be an alternative to opioids
An experimental peptide-based drug targeted the same pain-relief receptors as morphine but had fewer side effects and is unlikely to be addictive, researchers at Tulane University and Southeast Louisiana Veterans Health Care System reported in the journal Neuropharmacology. Science World Report (1/31)
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Industry Report
GlaxoSmithKline broadens immunotherapy deal with Adaptimmune
GlaxoSmithKline and Adaptimmune Therapeutics are broadening their cancer immunotherapy partnership to advance GSK3377794, an enhanced T-cell immunotherapy that targets NY-ESO-1, into pivotal trials for synovial sarcoma and study the drug's potential against myxoid round cell liposarcoma. Under the modified deal, Adaptimmune is entitled to receive about $500 million in milestone payments if GSK successfully develops the treatment for at least two disease indications and at least two human leukocyte antigen types. PharmaTimes (U.K.) (2/2)
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FDA clears ARIAD Pharmaceuticals' application for lung cancer treatment
The FDA has approved ARIAD Pharmaceuticals' investigational new drug application for AP32788, a tyrosine kinase inhibitor designed to treat non-small cell lung cancer patients with EGFR or HER2 mutations. A Phase I/II trial could be initiated in the second quarter of this year. Zacks (2/2)
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News from the Field
Regulatory changes tied to burnout
Provider burnout has been experienced by 90% of physicians, while almost two-thirds of that group reported thinking about leaving the profession, according to a report from the Studer Group. Among the major causes cited were staff shortages and the regulatory burdens of EHR meaningful use measures and the ICD-10 transition. EHR Intelligence (2/2)
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Health Policy
Administration's 2017 budget calls for drug addiction treatment, prevention
President Barack Obama has included $1 billion in his 2017 budget plan to increase access to heroin and opioid addiction treatment for two years. The proposal also seeks about $500 million to help the Justice Department and HHS expand drug overdose prevention efforts. Part of the funding would go to an HHS project promoting buprenorphine prescriptions by nurse practitioners and physician assistants. MedPage Today (free registration) (2/2), McClatchy Washington Bureau (2/2)
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Grants and Funding
Foundation awards $400K for clinical genomics study
Geisinger Health System will use a $400,000 grant from the Robert Wood Johnson Foundation to study how patients and doctors can use genomic information in health care. Geisinger researchers integrate genomic testing results into the care plans for 300 patients, focusing on familial hypercholesterolemia, hereditary breast and ovarian cancers, and hereditary nonpolyposis colorectal cancer. GenomeWeb Daily News (free registration) (2/2)
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Advancing Health Care
Hospital offers tablets to inpatients to boost their health resources, EHR access
Inpatients at West Chester Hospital in Ohio are now able to use Samsung tablet computers at the facility, as part of its My UC Health Bedside initiative, to easily access their health records. The tablets will also provide access to educational resources on topics related to patients' conditions and allow them to submit questions to members of their care teams. American City Business Journals/Cincinnati (2/1)
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From SNMMI
Try out SNMMI's tools to calculate radiation dose and pediatric injected activity
Did you know SNMMI has online tools to help educate imaging professionals on best practices for adult and pediatric nuclear medicine? The Nuclear Medicine Radiation Dose Tool provides convenient access to guidelines and radiation dose estimates (effective dose and critical organ dose) for many nuclear medicine exams. The Pediatric Injected Activity Tool reports recommended injected activity for pediatric patients. Visit www.snmmi.org/dose today!
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Student Technologist Registry Review taking place at SNMMI's Annual Meeting
This course is designed as a review for nuclear medicine technology students and others preparing to sit for the Nuclear Medicine Technology Certification Board (NMTCB) and/or the American Registry of Radiologic Technologists (ARRT) examinations. The course includes an eight-hour review session on Saturday, June 11, and a mock registry examination on Sunday, June 12, during SNMMI's 2016 Annual Meeting in San Diego.
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SmartQuote
The thing that makes you say, 'I want to do something' -- that is the beginning of talent."
-- Stella Adler,
actress and teacher
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The news summaries appearing in SNMMI SmartBrief are based on original information from multiple internet sources and are produced by SmartBrief, Inc., an independent e-mail newsletter publisher. The items above are not selected or reviewed by SNMMI prior to publication. Questions and comments may be directed to SmartBrief at snmmi@smartbrief.com.
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