Researchers examined more than 1,200 African-Americans ages 65 and older who received ACE inhibitors, beta blockers, calcium channel blockers or diuretics for hypertension found that reduced blood pressure, and not antihypertensive drugs themselves, was associated with a lower likelihood of dementia. The findings in the Journal of General Internal Medicine suggest that BP control at all ages may curb dementia risk, said researcher Michael Murray.
Research published in Lancet Psychiatry found patients who had any type of traumatic brain injury had a 24% higher risk of dementia than those who did not experience a TBI. Even experiencing one mild TBI increased the risk of dementia by 17%.
Forty genes have been identified by investigators from London's Institute of Cancer Research that could become potential therapeutic targets. As reported in the journal Leukemia, the researchers were able to pinpoint coding and noncoding mutations linked to the development of multiple myeloma while examining whole-genome sequencing data from 765 patients.
A study in JAMA Pediatrics showed that babies whose mothers took selective serotonin reuptake inhibitors for depression during pregnancy had significantly increased brain volume in the right amygdala and right insula, which are involved in emotional processing, as well as significantly greater connectivity between both brain regions, compared with those whose mothers had untreated depression and those whose mothers didn't have depression. The findings should prompt "further research on the potential long-term behavioral and psychological outcomes of these neurodevelopmental changes," researchers said.
Selinexor, Karyopharm Therapeutics' treatment for patients with multiple myeloma who have undergone at least three previous lines of therapy, was granted fast-track designation by the FDA. Top-line data from a study evaluating the drug is expected to be released by the end of the month.
An American Heart Association policy statement published in the journal Circulation estimated the cost of informal caregiving for patients with cardiovascular disease will increase from $61 billion in 2015 to $128 billion in 2035. The AHA called for the development of a national caregiving strategy, expanded access to palliative care, the incorporation of outcomes and caregiver engagement to payment reforms, and prioritizing caregiving research.
Medicare Payment Advisory Commission members discussed expanding incentives for health care providers participating in advanced alternative payment models under the Medicare Access and CHIP Reauthorization Act in an effort to encourage more participation. The commission proposed paying a 5% bonus only on certain revenue derived from an AAPM.
Specialist-focused EHR products for categories such as nephrology, cardiology, addiction medicine and endocrinology received the highest satisfaction scores in a Black Book survey of 18,950 physician practices. Epic Systems received the highest satisfaction scores in neurosurgery, transplant medicine and nephrology, athenahealth ranked highest in endocrinology, and NextGen scored highest for multispecialty clinics, general practice, and obstetrics and gynecology.
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Ignoring isn't the same as ignorance; you have to work at it.
Margaret Atwood, writer
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