FDG-PET/CT sheds light on metabolic activity in patients with GLILD | Crohn's may increase thyroid cancer risk, study says | Researchers examine incidence of cancer with HIV
December 2, 2016
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FDG-PET/CT sheds light on metabolic activity in patients with GLILD
Researchers from the University Hospital of Wales who used FDG-PET/CT found that patients with common variable immunodeficiency who developed granulomatous lymphocytic interstitial lung disease had increased and widespread metabolic activity in the lungs and lymph nodes before receiving treatment, but functional and anatomical activity improved after treatment. The findings in a proof of concept study in Clinical & Experimental Immunology suggest the approach may have a role in monitoring CVID patients with GLILD, but further studies are needed, researchers said.
News-Medical.Net/News release (11/30) 
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Clinical News & Research
Crohn's may increase thyroid cancer risk, study says
Data suggests that Crohn's disease patients, but not those with ulcerative colitis, may have a higher risk of thyroid cancer, compared with those who have diverticulitis, chronic constipation and atonic colon, researchers reported in the journal Inflammatory Bowel Diseases.
Healio (free registration)/Gastroenterology (11/29) 
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Researchers examine incidence of cancer with HIV
A study in the Journal of Cancer Epidemiology found that HIV-positive individuals receiving antiretroviral therapy had 46 times higher incidence of Kaposi sarcoma, 4.2 times greater incidence of non-Hodgkin lymphoma, 30.5 times greater incidence of anal cancer and 9.8 times greater incidence of Hodgkin lymphoma compared with the general population. The study, based on data for 63,221 commercially insured adults, found a lower incidence of prostate, lung and colorectal cancers among HIV-positive people than the general population.
Renal and Urology News (11/28) 
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Researchers develop cheap, easy test for blood cancer
A research team at the Fred Hutchinson Cancer Research Center says it has developed a test for chronic myeloid leukemia that uses a few dime-size spots of blood on a paper card that can be submitted through the mail. The test was spawned by a summer project for high school and college students.
The New York Times (free-article access for SmartBrief readers) (11/28) 
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The Truth about Cloud Security
72% of businesses are using the cloud. 56% said they are still figuring out exactly where they can use the cloud more. Why would so many businesses already trust these services with their own and their clients' most sensitive data? While security risks are real, the cloud is also more secure than you think. Read this eBook to learn more
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Industry Report
FDA fast-tracks review of Merck KGaA's avelumab for aggressive skin cancer
The FDA will review Merck KGaA and Pfizer's application for avelumab to treat metastatic Merkel cell carcinoma within six months instead of the typical 10, according to Merck.
Reuters (11/29) 
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EU grants conditional approval to Takeda's multiple myeloma treatment
Takeda Pharmaceutical's Ninlaro, or ixazomib, has received conditional approval from the European Commission for use along with lenalidomide and dexamethasone as a treatment for multiple myeloma in adult patients who have received at least one previous therapy. Late-stage study data showed the combination treatment improved median progression-free survival compared with only dexamethasone or lenalidomide.
OncLive (11/28) 
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Why Platform Matters When Choosing an ERP System
In order to survive, grow, and compete in the digital age, organizations need an ERP that is highly flexible and able to adapt. So, what are the tough platform questions you should ask yourself when shopping for an ERP?
Download the report to find out!
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News from the Field
Family history helps GCs determine patients' cancer risks
Some people are open about their medical histories, but others are not forthcoming, which complicates efforts to compile a family medical history, says certified genetic counselor Jessa Blount. A genetic counselor can help patients determine genetic cancer risks, explain how inherited and environmental factors raise cancer risk, assist with obtaining testing and insurance coverage and work with family members.
WALA-TV (Mobile, Ala.) (11/29) 
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Health Policy
21st Century Cures bill aims to push FDA to innovate
The 21st Century Cures bill would change how the FDA regulates drugs, medical devices and biologic medicines; and authorizes the agency to spend $500 million over 10 years on innovation projects. The bill directs the FDA commissioner to seek input on which projects to pursue from the agency's Science Board and to submit a work plan within 180 days to specific House and Senate committees.
Regulatory Focus (11/28) 
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Advancing Health Care
ONC, ACLA: Lab test HIT standard could improve EHR interoperability
Clinical practices could improve EHR interoperability and reduce costs by using the Laboratory Test Compendium Framework, a health IT standard for ordering laboratory tests and services developed by Health Level Seven International, according to the Office of the National Coordinator for Health IT and the American Clinical Laboratory Association. The framework's electronic Directory of Service "could dramatically reduce the manual effort to receive and integrate a laboratory partner's catalog of available tests and services into a provider's EHR," as well as provide support for ordering and grouping customization, the groups state.
Health IT Interoperability (11/28) 
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From SNMMI
Don't wait until the last minute. Save money on your registration now.
Make your plans now to attend the 2017 SNMMI Mid-Winter and ACNM Annual Meeting. Taking place Jan. 19-22 in Phoenix, the meeting themes include utilizing new FDA-approved radiopharmaceuticals; quantification of amyloid and tau; prostate cancer imaging and therapy; advances in nuclear cardiology technologies and protocols; radiation safety; and leadership and management in nuclear medicine. Early-bird registration ends Thursday, Dec. 8. Learn more and register today.
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Review abdominal case studies
ACNM and SNMMI have partnered to bring you the first-ever online MRI teaching modules as an introduction to interpreting MRI. The first set, Abdominal MRI Part I, is now available! Over the next year, ACNM/SNMMI will release five more sets of 25 cases covering abdominal II, pelvic, neurology, chest and oncology MRI. Each set of 25 cases offers CME/SAM credit upon completion of the course. Register for Abdominal Part I.
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The news summaries appearing in SNMMI SmartBrief are based on original information from multiple internet sources and are produced by SmartBrief, Inc., an independent e-mail newsletter publisher. The items above are not selected or reviewed by SNMMI prior to publication. Questions and comments may be directed to SmartBrief at snmmi@smartbrief.com.
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