Hybrids on the horizon for CAD detection | Engineered protein might prevent cancer from spreading | Study links healthy lifestyles to reduced heart attack risk in men
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September 23, 2014
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Hybrids on the horizon for CAD detection
Cardiac imaging experts hope hybrid imaging can replace invasive procedures for the assessment of coronary artery disease. One study reported in the Journal of Nuclear Medicine that looked at O-15 water PET combined with CT-based coronary angiography found the approach has the ability to rule out false positives and spare patients from invasive procedures. Further studies are exploring SPECT/CT vs. PET/CT, and another team, whose work was presented at this year's SNMMI Annual Meeting, is looking at a lower-dose approach using N-13 ammonia PET/MR stress perfusion imaging, which carries some added benefit such as collecting echocardiography data. MolecularImaging.net (9/16)
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Clinical News & Research
Engineered protein might prevent cancer from spreading
A study in the journal Nature Chemical Biology has shown that a new protein could stop cancer from spreading by targeting the Axl and Gas6 proteins, which allow cancer cells to leave the original tumor site. They created an inert decoy protein that binds to Gas6 proteins, preventing them from activating the true Axl proteins on cancer cells. The therapy reduced metastatic nodules in mice with breast cancer by 78% and in mice with ovarian cancer by 90%. Genetic Engineering & Biotechnology News (9/22)
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Study links healthy lifestyles to reduced heart attack risk in men
A study in the Journal of the American College of Cardiology showed that practicing five healthy behaviors such as exercising and drinking moderately could prevent four in five heart attacks in middle-aged and older men. Compared with overweight patients and those who ate poorly, exercised little, drank too much alcohol and smoked, participants who followed the recommended health behaviors were 86% less likely to experience heart attacks. HealthDay News (9/22)
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Industry Report
ILife signs genetic testing deal with OvaGene
India-based iLife Discoveries has entered into a research and marketing deal with OvaGene for undisclosed terms. The deal calls for the companies to validate and offer on the Indian market gene-based tests that target cervical, endometrial and ovarian cancer. GenomeWeb Daily News (free registration) (9/19)
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News from the Field
Imaging access limited in some areas, study finds
Certain imaging modalities are not readily available at critical access hospitals across the country, according to a study published in a radiology journal. Almost 20% of the nation's population lives in rural areas whose only access to advanced imaging is at critical access hospitals. The study found 33% of states had ultrasound available at all critical access hospitals while no states had SPECT or PET/CT available at all facilities. Diagnostic Imaging (9/17)
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Cassen Prize winner shares views on the state of imaging
Dr. Barry Siegel, who won the Benedict Cassen Prize at the 2014 SNMMI Annual Meeting, shares his history, views on nuclear imaging and future plans and projects, including a focus in clinical applications of PET/MR. Siegel said major challenges for adoption of the hybrid modality are reimbursement and persuading payers of its value. However, he said registries offer an opportunity to collect evidence to support conversations with payers, although the programs are growing more costly. MolecularImaging.net (9/16)
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Health Policy
NIH takes steps to correct sex bias in clinical trials
The NIH is awarding $10 million to supplement ongoing research at hospitals and universities in an effort to better understand how medical conditions and treatment manifest differently in men and women. The move seeks to end long-standing tendency in preclinical research favoring male cell cultures and male animals. Reuters (9/23)
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Advancing Health Care
States push health care cost transparency
Fourteen states require health insurers to disclose their health care provider payment rates, and some, including New Hampshire, release the data to consumers in an effort to help patients make smarter choices. However, actual health care prices are difficult to find in many cases, and experts say many consumers need an incentive or disincentive from their insurer or employer to shop for health care. MedPage Today (free registration)/Kaiser Health News (9/21)
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From SNMMI
Apply for the 2015 SNMMI-TS Leadership Academy: Deadline extended until Sept. 30
The SNMMI-TS Leadership Academy is a two-day course of lectures and team-building exercises to enhance leadership skills and networking opportunities. Each lecture will consider a different aspect of leadership and will be led by technologists or keynote speakers with an intimate knowledge of the subject. The application deadline has been extended until Sept. 30. Submit your application today!
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Prepare for the NMTCB's Nuclear Cardiology Specialty exam
Use SNMMI's new NCT Online Review Workshop to strengthen your knowledge of cardiac anatomy, physiology, pathology and electrophysiology and ace the NMTCB's nuclear cardiology specialty examination. VOICE credit available. Learn more.
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SmartQuote
Art is a marriage of the conscious and the unconscious."
-- Jean Cocteau,
French writer
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The news summaries appearing in SNMMI SmartBrief are based on original information from multiple internet sources and are produced by SmartBrief, Inc., an independent e-mail newsletter publisher. The items above are not selected or reviewed by SNMMI prior to publication. Questions and comments may be directed to SmartBrief at snmmi@smartbrief.com.
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