Delivery traits tied to early-onset sepsis risk in extreme preemies | Preemies may benefit from higher vitamin D dose | Low-dose epidural does not increase duration of labor
October 12, 2017
National Association of Neonatal Nurses SmartBrief
News for Neonatal Care Professionals
Neonatal Care
Delivery traits tied to early-onset sepsis risk in extreme preemies
A study in Pediatrics found that delivery characteristics such as cesarean delivery, membrane rupture at delivery and absence of clinical chorioamnionitis helped identify extremely preterm infants who were significantly less likely to develop early-onset sepsis. The findings may curb unnecessary early antibiotic use among nearly one in three low-risk babies, researchers said.
Physician's Briefing/HealthDay News (10/5) 
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Preemies may benefit from higher vitamin D dose
Researchers found that preterm infants who received an 800 IU daily dose of vitamin D had better bone density and vitamin D blood levels after four weeks, as well as improved growth associated with significantly lower odds of developing very low bone density, compared with those who took 400 IU of vitamin D daily. The findings in PLOS ONE were based on data involving 32 babies born from 24 to 32 weeks of gestation.
KHGI-TV/KWNB-TV/KHGI-CD (Kearney, Neb.) (10/11),  KETV-TV (Omaha, Neb.) (10/11) 
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Health Policy & Practice
Higher inflammation risk found in infants with RSV exposed to secondhand smoke
Babies with respiratory syncytial virus bronchiolitis who were exposed to secondhand smoke had significantly increased overexpression of genes linked to inflammation, cell death and apoptosis in their blood, compared with those without secondhand smoke exposure, researchers reported at IDWeek 2017. The findings also showed that B-cell- and T-cell-related genes were more suppressed among those exposed to secondhand smoke.
Healio (free registration)/Infectious Diseases in Children (10/10) 
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Childhood stress more likely to affect later mental health of ELBW preemies
Adults born preterm with extremely low birth weight were more sensitive to childhood stress that may lead to later mental health problems such as depression and anxiety, compared with those with a normal birth weight, Canadian researchers reported in the Journal of Child Psychology and Psychiatry. However, the findings showed reduced mental health risks among those born preterm with ELBW who had lower exposure to bullying and family problems as children and adolescents.
Psych Central (10/5),  HealthDay News (10/5) 
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Trends & Technology
Gene variant and breastfeeding tied to lower risk of esophagitis
Infants with the CAPN14 gene variant who were breastfed had a 92% lower risk of eosinophilic esophagitis, while those who did not have the gene variant LOC283710/KLF13 and were admitted to a NICU had a higher risk for the disorder, according to a study in the Journal of Allergy and Clinical Immunology. Researcher Elizabeth Jensen said breast milk may play a role in disease prevention when barrier function in the gut is altered, although the underlying mechanism is unknown.
Healio (free registration) (10/11) 
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Tiny ultrasound device tracks brain activity in infants
A domino-size ultrasound scanner can detect abnormal brain activity and seizures through the anterior fontanelles in real time and could be used to monitor infants' brain function. Researchers reported in Science Translational Medicine that the probe distinguished active and quiet sleep, and, when combined with EEG, not only detected seizures in two at-risk infants but also identified where in the brain the seizures originated.
Science online (10/11) 
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Call for abstracts now open!
The National Association of Neonatal Nurses (NANN) Program Planning Committee invites you to submit an abstract to present at the 34th Annual Conference taking place Oct. 17-20, 2018 in Anaheim, Calif. A list of topics and areas of interest is available online. We encourage you to suggest your own ideas, present your own research findings, or share your knowledge on a topic of interest.
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Join NANN in Vietnam!
NANN is thrilled to announce a delegation to Vietnam March 3-10, 2018! This delegation offers a unique opportunity to meet directly with our Vietnamese counterparts as we learn about the challenges and advances of neonatal healthcare delivery in Vietnam. The delegation will convene in Hanoi, Vietnam, on March 3, 2018, returning to the United States after the program's conclusion on March 10, 2018, from Ho Chi Minh, Vietnam. Deadline to enroll is Dec. 3, 2017.
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