Pediatric constipation may be linked to parenting style | Weight gain, holiday meals can affect GERD, physicians say | Data show association between sleep apnea, NASH
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November 19, 2014
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Digestive Health SmartBrief
From Stanley K. Fergus and the American College of Gastroenterology

Top Story
Pediatric constipation may be linked to parenting style
A Dutch study found that parents' attitudes and child-rearing strategies may perpetuate chronic constipation in children. Psychologist Marieke van Dijk at Emma Children's Hospital in Amsterdam said physicians should talk with parents about how they may be contributing to their child's constipation problems. Another study published in the Journal of Pediatrics found that fussy eating habits in 4-year-olds were associated with functional constipation. Reuters (11/12)
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Guide to Healthy Living
Weight gain, holiday meals can affect GERD, physicians say
Losing 10 pounds may help reduce gastroesophageal reflux disease and gaining 10 can increase symptoms, said gastroenterologist Hiren Doshi. Holiday dinners often feature high-fat or spicy foods that can trigger GERD symptoms, and Dr. Allen Mask said adding fiber and probiotics to a diet, along with exercise, may help digestion. WRAL-TV (Raleigh, N.C.) (11/13)
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Data show association between sleep apnea, NASH
Massachusetts General Hospital researchers studied 213 patients enrolled in a weight-loss surgery program and found obstructive sleep apnea was tied to nonalcoholic steatohepatitis, steatosis, lobular inflammation and fibrosis. The data were presented at Obesity Week 2014. Healio (free registration)/Endocrine Today (11/13)
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Look beyond yogurt for healthy probiotics, nutritionist says
Yogurt is not the only food plentiful in probiotics or "good bacteria," which may aid the digestive and immune systems, says dietitian Molly Kimball. Buttermilk, kefir, kombucha, cottage cheese and sauerkraut also can contain probiotics, but Kimball says to read ingredient labels to make sure products contain live cultures. WGNO-TV (New Orleans) (11/12)
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People on gluten-free diet need to plan ahead for travel
People on a gluten-free diet must do significant planning before traveling to ensure they can eat safely, and their mode of travel will affect how much food they can bring along, dietitians said. Registered dietitian Lisa Cimperman at University Hospitals Case Medical Center in Cleveland said people can call ahead for special accommodations or contact a local celiac disease organization for help finding restaurants and stores that offer gluten-free options. Today's Dietitian (11/2014)
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Study links high-fiber diet to better health outcomes
University of Massachusetts researchers said counseling patients with metabolic syndrome on adopting a high-fiber diet may lead to better outcomes, such as weight loss and reductions in the consumption of sugars, fat, sodium and cholesterol. The study was presented at Obesity Week. Healio (free registration)/Endocrine Today (11/14)
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Diagnosis & Treatment
Combo drug for hepatitis C shows high cure rates in trial
A clinical trial showed Gilead Sciences' FDA-approved oral hepatitis C drug, a combination of sofosbuvir and ledipasvir, cured 96% to 97% of patients with genotype 1 virus and cirrhosis who failed to respond to previous treatments. Patients who took the combination drug plus ribavirin showed a 96% cure rate. Yahoo/Reuters (11/11)
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Prednisolone reduces mortality risks for patients with alcoholic hepatitis
A study presented at the Liver Meeting 2014 found prednisolone cut 28-day mortality risks for patients with severe alcoholic hepatitis but did not provide benefits after that time period. According to researchers from Imperial College London, pentoxifylline did not reduce mortality risks and should not be used in this patient group. Medscape (free registration) (11/14)
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Researchers study parasites for clues to IBD, other autoimmune diseases
Researchers such as Julius Lukes at the Canadian Institute for Advanced Research are studying whether parasites, including tapeworms, can play a role in controlling inflammatory bowel disease and other chronic autoimmune disorders. Lukes is among the researchers who are consuming parasites to investigate whether they can safely prime the immune system to not overreact to triggers such as gluten. The Globe and Mail (Toronto) (tiered subscription model) (11/14)
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Clinical Trial Monitor
A selection of U.S. based clinical trials seeking participants
Aflibercept and FOLFOX6 treatment for previously untreated Stage IV colorectal cancer
Alabama, Michigan, New York, North Carolina, Ohio, Virginia.
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Curcumin in treating patients with familial adenomatous polyposis
Maryland, Puerto Rico.
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Evaluating the efficacy, safety and tolerability of tenofovir DF in pediatric patients with chronic hepatitis B infection
Arizona, California, Colorado, New York, Ohio, Texas, Bulgaria, India, Korea, Poland, Romania, Taiwan.
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Phase 3 study with cadazolid in CDAD
Alabama, California, Colorado, Florida, Georgia, Idaho, Illinois, Indiana, Maryland, Massachusetts, Nebraska, New Jersey, New York, North Carolina, North Dakota, Ohio, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Virginia, Australia, Canada, France, Germany, Italy, Netherlands, Peru, Poland, Romania, Spain.
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Trametinib or combination chemotherapy in treating patients with refractory or advanced biliary or gallbladder cancer or that cannot be removed by surgery
Alaska, California, Connecticut, Florida, Idaho, Illinois, Indiana, Kansas, Kentucky, Massachusetts, Michigan, Missouri, Montana, Nevada, New Mexico, New York, North Carolina, Ohio, Oregon, South Carolina, Tennessee, Texas, Virginia, Washington, Wyoming.
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Did you know?
Constipation is common in children
"Various factors can lead to constipation in children. Common causes include early toilet training and changes in diet. Fortunately, most cases of constipation in children are temporary. Encouraging your child to make simple dietary changes -- such as eating more fiber-rich fruits and vegetables and drinking more fluids -- can go a long way toward alleviating constipation." -- Mayo Clinic
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The Last Word
News and information from the American College of Gastroenterology
NSAIDs and ulcers: How to avoid unsuspected damage
If you're one of millions who take NSAIDs for pain relief, you may be at risk for ulcers and GI bleeding. You can reduce the risk of these common side effects by following a few simple guidelines. Learn important safety tips on the use of NSAIDs.
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Featured Press Releases
Failure will never overtake me if my determination to succeed is strong enough."
-- Og Mandino,
American author
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Contact Your Doctor
Stanley K. Fergus
Gastroenterolgy Associates of West Tennessee
1400 Kings Boulevard
Memphis, TN 38105

Phone: (901) 555-1234
Contact ACG
American College of Gastroenterology
P.O. Box 342260
Bethesda, MD 20827-2260
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