Preliminary results of new Brazilian research show 13 of the 32 infants with microcephaly tested positive for Zika virus infection, while none of 62 controls without microcephaly was infected, according to a study published in The Lancet Infectious Diseases. Researchers also found that 41% of the infants with microcephaly had the Zika infection in their blood or cerebrospinal fluid, and 84% of those with microcephaly had low birth weight.
An Australian prospective cohort study found current and past users of bisphosphonates, particularly alendronate, were at reduced risk of all-cause mortality even after adjusting for baseline factors. The findings were presented at the American Society of Bone and Mineral Research's annual meeting.
Children born to mothers who smoked at least 10 cigarettes daily during gestation were 66% more likely to develop Tourette's syndrome and other chronic tic disorders, compared with those whose mothers didn't smoke. The findings in the Journal of the American Academy of Child and Adolescent Psychiatry, based on data involving more than 73,000 births in Denmark, also showed a twofold to threefold higher risk of chronic tics combined with psychiatric conditions such as attention-deficit/hyperactivity syndrome among those whose mothers smoked heavily during pregnancy.
Maternal mortality is rising in Sierra Leone, and bleeding causes 4 out of 10 of the deaths, taxing the country's blood supply. Clinicians must search for donors when women need a transfusion, and "by the time you find one, the woman will most likely be dead," said reproductive and child health official Santigie Sesay.
In a new study from National Institutes of Health, women who reported feeling depressed during the first two trimesters of pregnancy were nearly twice as likely to develop gestational diabetes. Although obesity is known to increase the risk for gestational diabetes, the likelihood of gestational diabetes was higher for non-obese women reporting depression than for obese women with depression. Read the abstract in Diabetologia.
Researchers examined 560 extremely preterm and full term infants and found that those born at 28 weeks of gestation or earlier had a significantly higher risk of having small airway obstruction at ages 8 and 18 and also a greater increase in small airway obstruction between ages 8 and 18 than those born full term. The findings in the journal Thorax also showed worse lung functioning at ages 8 and 18 among premature babies who had lung damage linked to respirator or long-term oxygen use, compared with premature babies who didn't have lung damage.
One-month-old babies with lower levels of four commensal gut bacteria groups and increased levels of two fungi types were three times as likely to develop allergic reactions by age 2 and asthma by age 4, compared with those without abnormal gut microbiomes, according to a study in Nature Medicine. The findings, based on stool samples of 298 infants in Detroit followed until age 4, also showed that those at-risk had the 12,13-DiHOME lipid linked to suppressing T cells that could help curb allergies.
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On Sept. 22, AACN and partners are hosting a free webinar where you can learn more about federal response to pain management and the intersection of opioid use as well as earn CE. Specifically, this webinar will address the CDC Guideline for Prescribing Opioids for Chronic Pain and the National Pain Management Strategy. Register today.