Study links sudden cardiac death risk to thyroid hormone levels | Women with depression at higher gestational diabetes risk, study finds | Study: BP, CVD risk should be considered in hypertension diagnosis, treatment
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September 21, 2016
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Study links sudden cardiac death risk to thyroid hormone levels
A Dutch study of 10,318 adults ages 45 and older with normal thyroid function found those with higher free thyroxine levels had more than double the risk of sudden cardiac death. The link between high FT4 levels and sudden cardiac death was independent of high blood pressure, high cholesterol and other cardiovascular risk factors, researchers reported in Circulation.
CardiovascularBusiness.com (9/20) 
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Women with depression at higher gestational diabetes risk, study finds
A study in the journal Diabetologia showed that women with depression during the first or second trimester of their pregnancy had a 1.72 times greater risk of developing gestational diabetes, with a higher risk seen among women who weren't obese before pregnancy than women who were obese. Researchers evaluated 2,477 pregnant women and also found those who had gestational diabetes had a 4.62 times increased risk of developing postpartum depression.
United Press International (9/19) 
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Medical Focus
Study: BP, CVD risk should be considered in hypertension diagnosis, treatment
A study in JAMA Cardiology suggests clinicians need to consider a patient's blood pressure and cardiovascular disease risk factors, rather than use clinical trial criteria, to diagnose hypertension and decide on a treatment approach. The findings, based on data for 14,142 adults ages 20 to 79, showed that having a systolic blood pressure of 120 mm Hg to 139 mm Hg or a high risk for cardiovascular diseases would not qualify many patients for the Systolic Blood Pressure Intervention Trial or the Heart Outcomes Prevention Evaluation-3 trial.
Medscape (free registration) (9/16) 
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Extreme prematurity tied to increased high BP risk in adulthood
Researchers found that young adults born very preterm had smaller kidneys and average systolic blood pressure that was 5 points higher than those born full term. Another study showed slower endothelial cell colony formation involved in creating new capillaries among those born at 29 weeks of gestation or earlier compared with those born full term. Both studies were presented at the American Heart Association meeting.
HealthDay News (9/15) 
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Regulatory & Policy
Aralez's Yosprala wins FDA nod
Aralez Pharmaceuticals' Yosprala, or aspirin and omeprazole, has been approved by the FDA for patients who take daily aspirin to prevent secondary cardiovascular events and are at risk for gastric ulcers caused by aspirin. Two clinical trials showed patients who received the drug had fewer endoscopic gastric ulcers compared with those who received enteric-coated aspirin.
Reuters (9/15),  MedPage Today (free registration) (9/15) 
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Next-Gen ACO benchmarks should apply to MSSP, experts say
Medicare Shared Savings Program cost benchmarks should account for national and regional spending trends as the Next Generation accountable care model does, with adjustments capped at 3.5% to boost participants' chances of success, according to a study in The American Journal of Accountable Care. MSSP participants' benchmarks are recalculated every three years and are lowered as health care spending declines, and changing the benchmark calculation would remove the correlation between prior performance and an ACO's savings, the study authors say.
RevCycle Intelligence (9/19) 
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