Fibromyalgia patients were found to have chronic systemic inflammation affecting the body, brain and spinal cord, but researchers said they were not sure if it causes the disease or is a consequence of it, according to a study in the Journal of Pain Research. Researchers said related factors such as depression, sleep problems and stress may be factors in the higher inflammation levels.
Researchers are using CRISPR-Cas9 gene-editing technology to study how regulating genes that reduce inflammation may help manage chronic pain. Their work, published in the journal Tissue Engineering, includes development of a virus to deliver the gene therapy.
A Millennium Health study suggests postoperative pain is often mismanaged or undertreated in hospital patients. About one-third of patients were given injectable opioids for uncontrolled postoperative pain.
An FDA advisory panel voted 18-8 that the benefits of Endo Pharmaceuticals' Opana ER painkiller do not outweigh the drug's risks, and some panelists said the drug should be removed from the market or reformulated again.
Primary care clinics associated with Virginia Mason Memorial in Yakima, Wash., are part of a study to track opioid prescriptions and create guidelines for managing patient pain. Prior to the study, Memorial was working to reduce opioid prescribing through use of a patient registry, prescription limits and policies that emphasize trying non-narcotic therapies first and creating realistic goals for pain and function.
The American Medical Association warns that the GOP's Affordable Care Act repeal bill could be a setback in the battle against the nation's opioid epidemic. Medicaid changes "that limit the ability of states to respond to changes in demand for services threaten to force states to limit coverage and increase the number of uninsured," said AMA CEO James Madara.