Brain natriuretic peptides are not involved in acute, inflammatory or neuropathic pain, researchers reported in Molecular Pain. "For us, it's very important to understand the neural circuits or pathways so that we can develop therapies specifically for pain or itch, instead of targeting it as a whole system," said North Carolina State University researcher Santosh Mishra, who said that targeting BNP will be inhibiting itch.
Purdue Pharma and Geisinger will test whether the Apple Watch can affect chronic pain. Patient biomeasures tracked by the watch and accompanying pain app will be used to increase understanding of chronic pain, and could inform medical decision-making and reduce the need for pain medication.
Youths who took ibuprofen for pain relief after undergoing minor outpatient orthopedic surgery had similarly reduced pain scores but significantly fewer adverse effects such as drowsiness, nausea, dizziness, vomiting and constipation compared with those who took oral morphine, according to a study in the Canadian Medical Association Journal. However, the findings showed that neither drug provided complete pain relief, prompting researchers to suggest further studies on better treatments.
A study in the Annals of Internal Medicine that involved patients with complex regional pain syndrome found they did not see better pain relief with low-dose intravenous immunoglobulin compared with a placebo. Researchers said using a higher dosage could be studied, but overall, alternative treatments are needed for this rare but serious condition.
Physicians and patients say a proposal from Florida Gov. Rick Scott to limit opioid prescriptions to three days is too broad and could make it difficult to treat people with chronic pain or life-limiting conditions. Anesthesiologist Dennis Patin said the proposal is not feasible due to a lack of pain specialists to handle an increase in visits, and Patin called on the Legislature to seek input from pain specialists and patient advocates.
The ongoing opioid epidemic in the US prompted the CDC to improve public health data reporting and collection to allow for real-time crisis response, and the agency is working with state health departments to boost prescription drug monitoring programs and other prevention initiatives, said Dr. Debra Houry, director of the CDC's National Center for Injury Prevention and Control. "We are now releasing preliminary overdose data and have improved reporting significantly from a lag of two years down to seven months" and have ramped up efforts to gather data from medical professionals, Houry said.
The Rita Allen Foundation and APS announce the 2018 Award in Pain and may award two grants in the amount of $50,000 annually, for a period of up to three years, to those research proposals demonstrating the greatest merit and potential for success. To learn more about the Rita Allen Foundation Award in Pain, please visit the APS website.
The Scientific Summit is the meeting for pain professionals across all disciplines that focuses on the theme Understanding Pain Mechanisms. This meeting provides a unique opportunity to take a deeper dive into pain and pain treatment mechanisms and will fully explore the theme through plenary lectures, focused symposia, poster sessions and exhibits. Registration opens Oct. 16! Learn more.