Subclinical thyroid disease and mortality risk | Gender differences in youths with eating disorders | Discordant pregnancy intentions in couples
April 28, 2016
AJM: From the publisher of The American Journal of Medicine
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Subclinical thyroid disease and mortality risk
The association between subclinical hypothyroidism and hyperthyroidism and mortality in the elderly is poorly defined. This study was designed to evaluate the association between subclinical hypothyroidism and subclinical hyperthyroidism and mortality in the elderly and to define the thyroid-stimulating hormone values associated with excess mortality in the elderly.
The American Journal of Medicine (4/2016) 
Free Idiopathic Pulmonary Fibrosis (IPF) CME Webcast from Elsevier!
This CME program brings clinicians up-to-date on the management of patients with IPF for optimal outcomes. Upon completion, you may receive up to 1.00 AMA PRA Category 1 Credit(s) . Click here to begin this activity!
Clinical Updates
Gender differences in youths with eating disorders
Female youths with eating disorders are more likely to present for treatment at an older age with an accompanying mood disorder, whereas male youths with eating disorders are more likely to present with an atypical diagnosis.
Journal of Adolescent Health (4/2016) 
Discordant pregnancy intentions in couples
More than maternal pregnancy intention, paternal intention highly influences rapid repeat pregnancy. Findings highlight the importance of considering partner pregnancy intention in reproductive discussions.
American Journal of Obstetrics & Gynecology (4/2016) 
Maternal obesity affects inflammatory and iron indices in umbilical cord blood
Prepregnancy maternal obesity is known to contribute to the development of allergic asthma, obesity and adult hypertension in offspring. In this study, the authors sought to determine the impact of maternal obesity and gestational weight gain across pregnancy on fetal inflammation and iron status through umbilical cord blood analysis after cesarean delivery. As maternal BMI at delivery increases, iron levels decrease. Maternal class II obesity (BMI of 35 kg/m2 and above) predict higher levels of inflammatory markers in fetuses. Maternal BMI at delivery could play a role in inflammatory patterns and chronic health risks in childhood.
The Journal of Pediatrics (4/2016) 
Low testosterone levels and reduced kidney function
Low testosterone levels and reduced kidney function -- is there an association? 848 Japanese males (mean age 69) were studied by measuring salivary testosterone and estimated glomerular filtration rate. Lower testosterone was found to be associated with reduced kidney function. A longitudinal study should be done to corroborate the evidence.
Journal of the American Medical Directors Association (4/2016) 
Safety of deep vein thrombosis home treatment
Cautious exploration of the safety of home treatment of deep venous thrombosis has been recommended by many. The authors' goal was to identify categories of patients with deep venous thrombosis who typically are hospitalized and categories frequently treated at home.
The American Journal of Medicine (4/2016) 
Opinions of adolescents and parents about pediatric biobanking
This survey assesses the opinion of adolescents and their parents from different settings in regard to biobanking. Although this research is exploratory, it provides a basis for further investigations and initial evidence for future policymaking.
Journal of Adolescent Health (4/2016) 
Medical News
High prevalence of comorbidities seen in type 2 diabetes, study finds
Researchers looked at 1,389,016 US adults with type 2 diabetes, mean age of 65, and found that 97.5% had at least one comorbid condition, while 88.5% had at least two. The findings in the journal Current Medical Research and Opinion showed that the most common comorbidities were hypertension, overweight or obesity, hyperlipidemia, chronic kidney disease and cardiovascular disease, and there was a sixfold increase in the co-prevalence of CKD and CVD from the youngest to oldest age groups.
Healio (free registration)/Endocrine Today (4/25) 
Study: Fish oil supplements may aid antidepressant therapy
Patients who took omega-3 fish oil supplements along with their antidepressants saw significantly better results than those taking a placebo with the medication, Australian researchers reported in the American Journal of Psychiatry. The study analyzed data from eight clinical trials and other evidence.
HealthDay News (4/26) 
Business Practice News
Doc discusses how physician-patient relationship is affected by EHRs
EHRs may have a negative effect on the physician-patient relationship because patients may perceive that the doctor is spending more time at the computer and giving them less attention, writes physician Cheryl Branche in the journal Medical Economics. Branche notes that some doctors also do not like EHRs and the data-entry tasks involved. News (4/25) 
Study validates HF readmission risk prediction model
A study in JAMA Cardiology validated the efficacy of a readmission risk prediction model for heart failure patients that includes socioeconomic factors, mental health, cognitive function and clinical measures. The study found the model had better discriminatory power than a claims-based model and was a good predictor of 30-day mortality and readmission.
Healio (free registration)/Cardiology Today (4/25) 
Nurse schedules with night shifts linked to heart disease risk
A study in the Journal of the American Medical Association found that nurses who worked three or more night shifts per month have a greater likelihood of developing heart disease over 24 years, compared with nurses who only worked daytime shifts. Nurses who worked night shifts for fewer than five years had a 12% increased risk of coronary heart disease, while nurses who worked night shifts for over 10 years had a 27% increased risk, although risk levels returned to normal after the nurses stopped working nights or retired.
Reuters (4/26) 
Patient's Perspective
Analysis: Aspirin linked to lower risk of dying from certain cancers
Researchers reviewed data from 47 studies and found that patients who took low-dose aspirin after treatment for colon, breast or prostate cancer had about 15% to 20% decreased risk of mortality from the diseases, study leader Peter Elwood said. The use of the drug was also associated with a reduction in metastasis, according to the study in the journal PLOS ONE.
Medscape (free registration) (4/22),  HealthDay News (4/20) 
You are too important to the bigger picture to just fall off the canvas.
Johnnie Dent,
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