Melinta to seek approval for skin infection treatment | Renaissance sells topicals business to Mylan for $1B | ConvaTec reportedly considering IPO
May 18, 2016
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Wound Care Update
Melinta to seek approval for skin infection treatment
Melinta Therapeutics announced plans to file two new-drug applications with the FDA in the next half of the year for intravenous and IV-to-oral formulations of Baxdela, or delafloxacin, for the treatment of acute bacterial skin and skin structure infections. The drug achieved the primary goals of two late-stage studies.
BioCentury (5/12) 
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Renaissance sells topicals business to Mylan for $1B
Renaissance Acquisition Holdings' topical products business will be acquired by Mylan in a deal worth about $1 billion, broadening Mylan's dermatological product portfolio. The acquisition could close within the third quarter of this year.
Reuters (5/13),  Bloomberg (5/13) 
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ConvaTec reportedly considering IPO
Medical device maker ConvaTec has contacted investment banks ahead of an initial public offering on the London Stock Exchange that could raise more than $1 billion, according to sources familiar with the matter.
Reuters (5/13) 
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Research, Technology & Innovation
Study shows need for cognitive screening in patients with DFU
Patients with diabetic foot ulcers had lower scores on cognition tests than their peers with diabetes but no foot ulcers, highlighting a need to screen DFU patients for cognitive impairment, researchers reported in Diabetes Care. The case-control study showed that DFU patients had lower scores on memory, executive function, reaction time, attention and psychomotor tests; and cognitive abilities had declined among cases while remaining stable in controls.
Healio (free registration)/Endocrine Today (5/17) 
Researchers identify another way wounds heal
Wounds heal not only by replacing lost cells through cell division but also by maintaining the size and function of injured tissue by enlarging existing cells, according to research led by Vicki Losick, an assistant professor at Mount Desert Island Biological Laboratory. Losick discovered the mechanism, which she calls wound-induced polyploidy, in fruit flies and confirmed with Johns Hopkins University researchers that it also happens in mammals. The findings could lead to new research on genes or drugs to help promote healing.
Mainebiz (5/17) 
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Other News
Health Policy & Regulation
NPUAP changes "pressure ulcer" to "pressure injury"
The National Pressure Ulcer Advisory Panel announced it changed the term "pressure ulcer" to "pressure injury" in its staging system and revised staging definitions, but medical facilities should not rush to update terminology in their forms, policy and procedure manuals, educational materials and EHRs yet, writes nurse Jacqueline Vance. The federal government requires care facilities to follow the Resident Assessment Instrument Manual, which has not changed, Vance notes. However, long-term care facilities will need to harmonize staging with associated hospital systems and wound care centers, she writes.
McKnight's Long-Term Care News (5/17) 
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