CDC issues Zika warning for 12 sperm banks in Fla. | Allogenic stem cell transplant shows positive result in early-stage trial | NIDCR funds tissue regeneration projects
March 15, 2017
AATB SmartBrief
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CDC issues Zika warning for 12 sperm banks in Fla.
The CDC has cautioned women who used 12 sperm banks in South Florida to consider being tested for the Zika virus. Collections from as far back as June 15 have the potential to carry the virus, according to the agency. The CDC also warned that men from three Florida counties should refrain from donating sperm because of a small risk of spreading the virus.
The New York Times (free-article access for SmartBrief readers) (3/13),  NBC News (3/13),  ABC News/The Associated Press (3/13) 
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Ensure Efficacy of Heat-Sensitive Specimens
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Tissue Banking in the News
Allogenic stem cell transplant shows positive result in early-stage trial
TiGenix, a Belgian cell therapeutics company, said a Phase I/II trial found that patients who received 35 million-cell intracoronary infusions of AlloCSC-01, an allogenic stem cell therapy, in the week after an acute myocardial infarction had no major cardiac adverse events or deaths in the year after treatment. "This is the first trial in which it has been demonstrated that allogeneic cardiac stem cells can be transplanted safely through the coronary tree, and in the worst possible setting represented by patients with an acute heart attack with left ventricular dysfunction," said researcher Fernandez-Aviles of the Hospital General Universitario Gregorio Maranon in Madrid. (Germany) (3/13) 
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Government & Regulatory
NIDCR funds tissue regeneration projects
The National Institute of Dental and Craniofacial Research will direct $24 million toward the creation of collaborative research centers at the University of California at San Francisco and the University of Michigan. Researchers will study regeneration of head, mouth and facial tissues. (free registration) (3/7) 
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Clearance for Spineology's interbody fusion system widened by FDA
The FDA has given Spineology expanded clearance for its Elite expandable interbody fusion system, which is designed to be inserted into the disc space and expanded to facilitate indirect decompression and provide disc height restoration and column support. The clearance is for the inclusion of a 10-mm version of the system and for an indication to use the technology with allograft bone.
FDAnews (3/14) 
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Zika virus tied to heart problems in adults
The Zika virus has been linked to the development of severe heart conditions, including heart rhythm disorders and heart failure, among nine adults in Venezuela, according to a study to be presented at the annual meeting of the American College of Cardiology. The patients were treated for heart symptoms that began about 10 days after infection, and the only history of heart-related conditions among the nine was a case of well-controlled high blood pressure.
HealthDay News (3/9),  The Associated Press (3/9) 
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Zika virus attacks CNS, muscles, joints
The Zika virus attacks the patient's central nervous system, muscles, joints, lymph nodes and reproductive and urinary tracts as it moves from the bloodstream to other tissues, a study in rhesus macaque monkeys revealed. Moreover, the virus persists in affected tissue for at least five weeks, researchers reported in PLOS Pathogens. "Many of the important elements that we're interested in seem to translate from rhesus macaques to humans," lead author Alec Hirsch said.
The Oregonian (Portland) (3/12) 
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Study evaluates serological test for distinguishing Zika, dengue
A multiplexed serological test on a plasmonic gold nanoplatform has been developed by researchers at Nirmidas Biotech and Stanford University to detect IgA, IgG and IgM antibodies for Zika and dengue virus antigens, according to a report in the journal Nature Medicine. The test could improve the differentiation of Zika and dengue virus infection during pregnancy. (U.K.) (3/10) 
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Type 1 diabetes patients may benefit from stem cell transplants, study finds
Most patients who received autologous hematopoietic stem cell transplants as a treatment for type 1 diabetes were able to live free of insulin therapy for an average of 3.5 years, according to a study in the journal Frontiers in Immunology. The 21-patient study was conducted in Brazil, and researchers said they were able to identify an immune signature associated with a response to treatment. (U.K.) (3/8) 
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Registration for the 2017 QDSW is Now Open!
AATB's 2017 Quality and Donor Suitability Workshop will be held May 8-10 at the JW Marriott in Indianapolis, Ind. Register and book your hotel room today!
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Register now for AATB's March webinar!
Topic: A Gift Beyond Measure: The legal basis for an anatomical gift. Speaker: Christina W. Strong, Esq., principal attorney, Law Office of Christina Strong. Date/Time: March 23; 2-3 p.m. Eastern Time. Read more and register.
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