Data demonstrate Zika's persistence in body fluids, spread among households | Widow who donated husband's face gets some closure | 8-year-old boy to be recognized as tissue donor
November 15, 2017
AATB SmartBrief
News for the Tissue Banking Community
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Data demonstrate Zika's persistence in body fluids, spread among households
The median RNA detection rates for Zika virus were 11 days for urine, two weeks for serum and six weeks for semen, according to research presented at the annual meeting of the American Society of Tropical Medicine & Hygiene. The data were based on samples from 295 Zika-infected Puerto Rico residents. A second study's results indicated that about one-third of Zika patients' household contacts harbored evidence of infection, and about 10% contracted the virus within four months.
MedPage Today (free registration) (11/9) 
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Tissue Banking in the News
Widow who donated husband's face gets some closure
After Lilly Ross' husband died by suicide, she donated his organs and tissues, including his face, which went to another man who survived his own suicide attempt with a rifle. That patient was the Mayo Clinic's first face transplant recipient, and Ross recently met him.
ABC News/The Associated Press (11/10) 
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8-year-old boy to be recognized as tissue donor
Aidan Hooper of Edmond, Okla., died in an accident when he was 8 years old. Aidan, whose donated heart valves gave lives to two young girls, will be honored as a tissue donor in the 2018 Tournament of Roses Parade.
KOCO-TV (Oklahoma City) (11/13) 
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Government & Regulatory
EPA authorizes release of sterile mosquitoes in fight against Zika
The Environmental Protection Agency has given biotech firm MosquitoMate the go-ahead to release Wolbachia-infected male Asian tiger mosquitoes in 20 states and Washington, D.C., as part of a plan to combat the spread of mosquito-borne diseases such as the Zika virus and dengue. The lab-raised mosquitoes, which have undergone extensive testing conducted in California, Kentucky and New York, will no longer be able to breed successfully, thus reducing the wild mosquito population.
Nature (free content) (11/6) 
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FDA approves Merck's Prevymis for post-stem cell transplant infections
Prevymis, or letermovir, Merck's drug being developed for the prevention of cytomegalovirus infections in patients who have undergone bone marrow transplants, was approved by the FDA to be marketed in tablet and injection forms.
MedPage Today (free registration) (11/9),  Reuters (11/9) 
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Stem cell therapy used to treat boy with rare skin disease
Physicians in Germany and Italy collaborated to treat a critically ill 7-year-old boy with junctional epidermolysis bullosa, replacing 80% of the child's skin using genetically modified stem cells. Autologous skin cells were modified with a healthy copy of the LAMB3 gene using a retrovirus, according to a case report in the journal Nature.
The Denver Post/The Associated Press (11/8),  Science News (11/8) 
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Study explores factors that influence kidney transplant wait-listing
A study evaluating wait-listing for 1,057 patients who were referred for kidney transplant evaluation found African-American patients were less likely than white patients to be wait-listed for transplant, and wait-listing was positively associated with income, transplant knowledge and having a live donor. Wait-listing was negatively associated with factors including age, comorbidities, being on dialysis and low socioeconomic status, researchers reported at the American Society of Nephrology annual meeting.
Renal and Urology News/HealthDay News (11/6) 
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Study compares 5-year survival rates from old, young lung donors
A new study found that the age of the lung donor does not have a significant impact on the survival of younger recipients of double-lung transplants; however, the University of Louisville researchers observed that there was a higher mortality risk with older lungs for older single-lung recipients. The findings in the journal The Annals of Thoracic Surgery were based on an analysis of data from over 14,000 lung transplants between 2005 and 2014 performed on patients in the US ages 18 and up.
HealthDay News (11/9),  MedPage Today (free registration) (11/9) 
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PET/MRI approach shows promise in detecting infections in kidney transplants
A breakthrough technique developed by German researchers combining diffusion-weighted MRI and Ga-68 pentixafor PET, which targets the receptor protein CXCR4 found on leukocytes, determined that nine of 13 kidney transplant patients with complicated urinary tract infections had acute infection in their transplanted kidneys, while the remaining four had lower UTI or non-urological infections. The approach, described in the Journal of Nuclear Medicine, shows promise for noninvasive leukocyte detection in transplanted kidneys and may be used to better characterize inflammatory and infectious kidney diseases, researchers said.
Medical Xpress/News release (11/8) 
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Free Webinar!
Date/Time: Nov. 30, 2-3 p.m. ET
Topic: How To: CTBS, CEUs Recertification
Description: This free webinar will expound upon details surrounding the CTBS recertification process, specific CEU requirements, how to navigate your AATB Portal account and other frequently asked questions. This webinar is for those who have never recertified, have not had to recertify utilizing the online format and for those who just need a refresher.
Speakers: Jon Boyd, American Association of Tissue Banks.
Upcoming AATB Webinar
Date/Time: Dec. 6, 2-3 p.m. ET
Topic: Qualification to Clinical Application: Birth Tissue's Path from Delivery to Use
Description: This webinar will present a high-level overview of the growth and emersion of birth tissue in the tissue banking community. Three subject-matter experts will elaborate upon their organizations' processes -- from qualifying the donation and processing the tissue all the way to the clinical application.
Speakers: Chris Agle, UMTB Donor Services Foundation; Dr. Shabnam Namin, UMTB Biomedical Inc.; and Santiago Osorio, UMTB Biomedical Inc.
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