Obesity may elevate prostate cancer risk among black men | Analysis evaluates co-testing for spotting cervical cancer | Study links genes to risk of cardiac arrest in patients on dialysis
April 17, 2015
AANP SmartBrief
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Obesity may elevate prostate cancer risk among black men
Black men were nearly 60% more likely than white men to develop prostate cancer overall, but obesity increased the risk further among black men, according to a study in JAMA Oncology. The likelihood of prostate cancer was 103% and 28% higher among obese and normal-weight black men, respectively, compared with white men. Reuters (4/16)
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Analysis evaluates co-testing for spotting cervical cancer
A combination of human papillomavirus and Pap testing yielded the highest sensitivity rate for detecting cervical cancer compared with HPV test alone and Pap test alone, according to a retrospective analysis of data on 256,648 women reported in the journal Cancer Cytopathology. Co-testing also had the lowest false-negative rate at 5.5%. MedPage Today (free registration) (4/15)
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Study links genes to risk of cardiac arrest in patients on dialysis
U.S. researchers examined nearly 650,000 kidney patients who were on dialysis -- including 5,100 pairs of patients from the same family. In 4.3% of genetically related pairs, death in both patients was caused by cardiac arrest, compared with 2.6% in patient pairs who were not related. The findings appear in the Journal of the American Society of Nephrology. HealthDay News (4/16)
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Sleep apnea linked to cognitive decline, but CPAP appears to help
Older people with sleep apnea started showing signs of cognitive impairment about a decade earlier than those without the condition, a study in Neurology showed. Researchers found that the use of continuous positive airway pressure mitigated the effect, delaying the onset of mental decline by an average of 10 years. The New York Times (tiered subscription model)/Well blog (4/15), Reuters (4/15)
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Calif. health officials may declare the end of measles outbreak
The California measles outbreak that started in Disneyland in December may be declared officially over if no new cases are reported before a second 21-day incubation period ends today. More than 130 people in the state were sickened, according to public health officials. Reuters (4/16), HealthDay News (4/16)
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Pharmaceutical NewsAdvertisement
PPIs tied to increased kidney failure risk in older people
A Canadian study found that the use of proton pump inhibitors was associated with twice the risk of hospitalization for kidney failure among older people. The rate of hospitalization for PPI users was 13.49 for every 1,000 people annually compared with 5.46 for every 1,000 among nonusers. The findings were published in the Canadian Medical Association Journal. Reuters (4/16)
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Metabolizer phenotype affects asthma control with lansoprazole treatment
Researchers looked at the effect of metabolizer phenotype based on the CYP2C19 gene on asthma control in children and found that those with the poor metabolizer phenotype had worse asthma control after six months of lansoprazole treatment. The findings were published in the Annals of the American Thoracic Society. PhysiciansBriefing.com/HealthDay News (4/15)
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Amgen's drug for heart failure receives FDA approval
Amgen has obtained FDA approval for Corlanor, or ivabradine, as a treatment for chronic heart failure. The approval was supported by a study that demonstrated a lower risk of hospital readmission among patients treated with ivabradine, compared with placebo. Reuters (4/15)
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Emerging Trends, Products and TechnologiesAdvertisement
More U.S. teens are using electronic cigarettes
The use of electronic cigarettes tripled among middle- and high-school students from 2013 to 2014, CDC researchers wrote in the Morbidity and Mortality Weekly Report. The increase marked the first time e-cigarettes exceeded the popularity of other tobacco products among teens. HealthDay News (4/16)
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Unneeded tests may be common before cataract surgery
Cataract surgery
(Jay Directo/AFP/Getty Images)
An analysis of data on almost 441,000 Medicare patients who underwent cataract surgery in 2011 found that 53% of them were subjected to at least one preoperative test, despite ophthalmology guidelines that recommend against routine presurgical testing. The study in the New England Journal of Medicine also found that about a third of ophthalmologists ordered these tests for almost all of their patients. HealthDay News (4/15)
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Health Policy and Legislative News
Medicare reimbursement change signed into law
President Barack Obama has signed a measure that he said strengthens Medicare "because it starts encouraging payments based on quality, not the number of tests that are provided or the number of procedures that are applied but whether or not people actually start feeling better." The bill also eliminates the 21% cut in Medicare payments that was due to take effect this month. The Washington Post (tiered subscription model)/The Associated Press (4/16), Reuters (4/16)
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Should DNP students be required to publish? Student perspective
In the April "Point/Counterpoint" section of JNP, Sylvida Davis argues that being required to submit for publication prepares the DNP student as a clinician-researcher, shows proficiency and competence in DNP essentials, and contributes to the profession. Tara Kelly points out there aren't enough journals to handle the load and early publication may not be right for some projects. Read their discussion.
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If you are irritated by every rub, how will your mirror be polished?"
-- Rumi,
poet and theologian
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