Some 270 girls from 18 New Jersey high schools attended the Young Women in Bio event at Robert Wood Johnson Medical School to learn about careers in biomedical sciences. The event, organized by Janet Alder, an associate professor of neuroscience and cell biology at Robert Wood Johnson Medical School, featured a panel discussion and hands-on learning experiences.
7 keys: Put real-world evidence into action Life sciences organizations need to know how their therapies work in the real world once clinical trials end. And these seven key components to standardizing real-world data and analytics platforms are how they get started. Read the paper, Institutionalizing Real World Evidence.
Peggy Carroll worked as an oncology patient advocate in the pharmaceutical and biotechnology industries for three decades, recently joined Patient Alliances as a managing partner and founded the Fill Your Bucket List Foundation to fulfill adult cancer patients' wishes. Carroll says women should develop strong support networks and never be afraid to ask for help.
Holly Van Remmen, chair of the Aging and Metabolism Research Program at the Oklahoma Medical Research Foundation, received a one-year, $100,000 supplemental grant from the National Institute on Aging for her research on the link between Alzheimer's disease and accelerated sarcopenia, a disease in which the body loses skeletal muscle mass. "When we think of Alzheimer's disease pathology, we think of dementia, but a few newer studies indicate that the same mechanisms that cause dementia could affect other neurons and tissues throughout the body," said Van Remmen.
A five-year collaboration between the Beijing Genomics Institute and the University of Manchester in England will focus on synthetic biology and metabolic engineering of natural products to help promote industrialization, academic research and education. "Researchers from both sides intend to start with the Sc2.0 synthetic yeast as a tool to establish the workflow for high efficient construction and characterization of biosynthesis pathways of natural products, and will gradually extended to industrial strains," said Kristi Heim, senior director of BGI's business development and communications division.
Genomic analysis and data sharing should be integral parts of public health surveillance systems, including the One Health Initiative, according to Jennifer Gardy with the British Columbia Centre for Disease Control and Nick Loman with the Institute for Microbiology and Infection at the University of Birmingham. "Combining genomic data with data streams from enhanced One Health surveillance platforms presents an opportunity to detect the population expansions and/or cross-species transmissions that may precede a human health event," Gardy and Loman wrote in Nature Reviews Genetics.
The NIH awarded $1.7 million to associate professor of chemistry and biochemistry Anita Mattson at Worcester Polytechnic Institute for a study of potential treatments for persistent cancers. Mattson's research focuses on using silanediols to catalyze synthesis of molecules derived from fungi called chromanones, which could boost the efficacy of cisplatin.
The Cary Institute of Ecosystem Studies, the University of Georgia and North Carolina A&T State University will share a $2 million grant from the National Science Foundation to develop tools based on artificial intelligence for forecasting zoonotic disease outbreaks. The researchers, led by Cary Institute disease ecologist Barbara Han and NC A&T researcher Suzanne O'Regan, will develop models of pathogen host species, cross-species transmission and environmental characteristics that promote cross-species transmission.
A study in The New England Journal of Medicine found women who stopped using adjuvant endocrine therapy for estrogen receptor-positive breast cancer after five years had a steady rate of recurrences up to 20 years. The findings, based on data from 88 trials involving 62,923 women with ER-positive breast cancer, showed women with larger original cancers and at least four cancer-affected lymph nodes had a 40% recurrence risk over 15 years, while those with smaller cancers that didn't involve the lymph nodes had a 10% risk.
A five-year, $1 million initiative by the Massachusetts Life Sciences Center and Takeda Pharmaceuticals will provide funding and technical support to early-stage life science companies run by women. Two companies will be selected each year to receive $50,000 and executive coaching, mentoring, and access to entrepreneurs, investors and industry experts through the new MassNextGen program.
Internal women's networking groups are more effective when the group has a set mission and isn't just about socializing, according to Karen Quintos, chief customer officer for Dell. It's also important to include male colleagues in meetings to help them better understand the issues that women face in the workplace.