Researchers using a new polygenic hazard score test based on genetic data from more than 70,000 elderly people with and without Alzheimer's disease found that those who scored in the top 10% for risk had a more than three times higher chance of developing Alzheimer's disease and were more likely to develop the disease at an earlier age, compared with those in the lowest 10%. The findings in PLOS Medicine suggest the test may be used in identifying healthy older patients with the greatest risk of Alzheimer's disease, said researcher Dr. Rahul Desikan.
There were ambiguous recommendations in 83% of North American and European guidelines targeted at caring for survivors of nine common cancers, researchers found. The study in JAMA Internal Medicine showed 90% of guidelines called for physical examinations and medical history, 83% recommended imaging, 63% called for endoscopic procedures and 56% included tests for disease biomarkers.
A study in the journal Gut found black patients had higher levels of sulfidogenic bacteria in colonic mucosa than white patients, which could be associated with their higher risk of colorectal cancer. Researchers said black patients also had higher intake levels of fat and animal protein, which also correlated with higher levels of sulfidogenic bacteria.
End-stage renal disease patients may have a higher risk of death if they receive hemodialysis after radiofrequency ablation for liver cancer, compared with patients who were not dialyzed, a study in the Journal of Gastroenterology and Hepatology found. The risk of death was lower for patients ages 70 and younger than in older patients, researchers said.
A Technavio report predicts the worldwide market for SPECT imaging will be worth $1.5 billion by 2021 with a 5% compound annual growth rate. Cardiology comprised 35% of the market last year, while oncology represented 31% of the market, according to the report.
The FDA has approved Newron Pharmaceuticals' Xadago, or safinamide, as an add-on drug for patients with Parkinson's disease. Xadago is indicated for patients who already take levodopa/carbidopa but experience "off" episodes in which the treatment is not effective.
Massachusetts is just 4 percentage points away from reaching a nationwide goal of having 80% of adults ages 50 and older screened for colorectal cancer by 2018. Neil Maniar of the American Cancer Society said the remaining 4% represent population-based disparities and people who feel good and do not get tested, and he adds that increased public awareness and working with community groups on screening strategies can help.
The Government Accountability Office confirmed it will investigate the FDA's orphan drug program for potential abuses after three US senators requested the probe. The investigation, which is expected to begin in nine months, will include a request for a listing of drugs approved or denied orphan status by the FDA, an evaluation of whether reviews are consistent and an analysis of the FDA's ability to keep up with orphan drug applications.
The National Brain Tumor Society launched the Clinical Trial Finder, developed by brain tumor survivor Michael Wenger, to increase awareness about trials for brain tumor treatments and get more patients involved in them. The group also is working on programs to improve the research process, empower patients and give patients more input into development of clinical trials.
Save up to $255 off on-site rates when you register by Thursday, April 13, for the SNMMI Annual Meeting. This year's meeting--taking place June 10-14 in Denver -- features more than 150 scientific and CE sessions, 1,000+ scientific posters, a world-class exhibit hall and more. Plus, get exclusive attendee only, pre-meeting rates on the Virtual Meeting and Virtual Poster Hall when you register. Make your plans today!
ACNM and SNMMI have partnered to bring you the first-ever online MRI teaching modules as an introduction to interpreting MRI. The first set, Abdominal MRI Part I, is now available! Each set of 25 cases offers CME/SAM credit upon completion of the course. Register for Abdominal Part I.
We do not need magic to change the world. We carry all the power we need inside ourselves already: We have the power to imagine better.
J.K. Rowling, writer
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