UK researchers found that type 2 diabetes patients with poor medication adherence had a higher risk for cardiovascular disease than those with good medication adherence. The findings in Diabetes Care, based on a meta-analysis of eight observational studies involving 318,125 adult diabetes patients, also revealed an association between good medication adherence and reduced risks for all-cause mortality and hospitalization.
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Metabolically healthy adults who were overweight had a 26% higher risk of heart disease, compared with normal-weight adults, while those who were obese had a 28% higher risk, according to a study in the European Heart Journal. People with three or more heart risk factors had twice the likelihood of developing heart disease regardless of their weight, the study found.
A study in the Journal of the American College of Cardiology found patients with cancer had greater risks for arterial thromboembolism, heart attack and ischemic stroke six months after their diagnosis, compared with those who did not have cancer. The findings were based on Medicare linked-Surveillance Epidemiology and End Results Program data for 279,719 pairs of patients with cancer and matched controls.
Nine- and 10-year-olds who got an additional hour of sleep during weekdays had a 2.9% reduction in insulin resistance, 0.24% lower fasting glucose and 0.19% lower body mass index, which are risk factors for type 2 diabetes, compared with those who got less sleep, UK researchers reported in Pediatrics. However, the findings didn't show a link between sleep duration and HbA1C levels or cardiovascular risk.
A study of South Asian women in CMAJ Open showed a higher risk for gestational diabetes with increased maternal age, a family history of diabetes, higher pre-pregnancy weight and low diet quality. Researcher Sonia Anand said additional studies are needed to see if reducing pre-pregnancy weight and improving diet quality during pregnancy could reduce gestational diabetes rates in this patient population.
Sweet-tasting beverages that are low in calories may spark a greater metabolic response than drinks with more calories, according to a study in Current Biology. Researchers suggested the findings may help explain why some studies have shown links between artificial sweeteners and diabetes.
A study in The Lancet Diabetes & Endocrinology showed that adults with type 2 diabetes who were new users of SGLT2 inhibitors had reduced risks for severe hypoglycemia, cardiovascular mortality, all-cause mortality, major CV events and hospital events for heart failure, compared with those who used other glucose-lowering drugs. Researchers analyzed data from CVD-REAL Nordic involving 91,320 patients and found no differences for atrial fibrillation, non-fatal myocardial infarction and stroke between the two groups.
A study in Diabetes Care found that mean systolic blood pressure was 120.7 mmHg for adults with prediabetes and 121.8 mmHg for those with normoglycemia one year after receiving intensive systolic BP treatment, compared with 136.2 mmHg for those with prediabetes and 136.2 mmHg among those with normoglycemia in the standard systolic BP treatment group. The randomized trial included 9,361 adults with a mean age of 67.9.
Diabetes patients in an intensive aerobic exercise and dietary program saw a greater decrease in average A1C levels than those in a standard care group, and 73.5% required less diabetes medication, compared with 26.4% in the standard care group, according to a study in the Journal of the American Medical Association. Researchers said the improvements in the intervention group did not reach the threshold for equivalence to standard care but were "in a direction consistent with benefit."
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1.5 Credit Hours Despite well-established treatment guidelines, many patients with T2DM are not managed optimally and fail to achieve recommended levels of blood glucose control. Delays in initiating insulin, however, are common and may stem from both physician and patient barriers. Negative patient perceptions regarding insulin include complicated dosing regimens, fear of injections, and hypoglycemia. Clinician concerns include hypoglycemia, weight gain, and the misconception that elevated insulin increases cardiovascular risks. Learn more.