Study compares risk of CV events between patients with, without diabetes | Study: Gender not a factor in how stress affects coronary risk | Study: Not treating OSA may worsen blood glucose, heart measures
Patients with and without diabetes and without coronary artery disease had the same adjusted risk of myocardial infarction, cardiac death and mortality 4.1 years after undergoing coronary angiography, according to a study in Diabetes Care. Danish researchers used a cohort of 93,866 patients and found that 75.3% and 65.7% of patients with diabetes without CAD were treated with statins and aspirin, respectively, compared with 65.7% and 52.7% of patients without diabetes and CAD.
A study in The American Journal of Cardiology found no gender differences in how stress affects the risk of coronary heart disease. Researchers also found urinary cortisol levels were independently predictive of asymptomatic coronary heart disease.
Failing to treat obstructive sleep apnea may lead to poorer blood glucose and heart health measures, according to a small study in the Journal of Clinical Endocrinology and Metabolism. Researchers said people with moderate to severe OSA who stopped using a continuous positive airway pressure machine for one night had OSA symptoms and more fatty acids, sugar and cortisol in their blood, as well as increases in blood pressure and arterial stiffness.
Study data on more than 1.4 million Canadian adults ages 40 years and older showed a moderately increased risk of major cardiovascular events for those with prediabetes who were younger than 65, compared with those who had normal glucose measures, researchers reported at the American Diabetes Association's annual meeting. Researchers also said patients younger than 65 with recent-onset or longer duration diabetes had a higher risk for CV events than those with prediabetes.
An American Heart Association advisory published in the journal Circulation said a review of study data strongly indicates that lowering saturated fat consumption and replacing it with unsaturated fats will reduce cardiovascular disease. The advisory noted that some studies have disagreed about the adverse cardiovascular effects of saturated fat, and the issue has been hotly debated, so lead author Dr. Frank Sacks said the AHA wanted to clarify that research "overwhelmingly supports limiting saturated fat in the diet to prevent diseases of the heart and blood vessels."
People who slept in on weekends, or those who got more sleep on weekend nights than on weekday nights, had an average body mass index of 22.8, compared with 23.1 among those who did not engage in catch-up sleep, according to a study in the journal Sleep. South Korean researchers evaluated survey data on more than 2,000 people, ages 19 to 82, and found that each additional hour of sleep on weekends was tied to a 0.12 drop in BMI.
A study in the journal Preventive Medicine found that 19-year-olds had similarly low physical activity levels as 60-year-olds. The findings also showed that more than 25% of boys and 50% of girls ages 6 to 11 and more than 50% of boys and 75% of girls ages 12 to 19 did not meet World Health Organization recommendations of at least an hour of moderate-to-vigorous daily exercise.
Researchers evaluated 7,637 type 2 diabetes patients, mean age of 65, and found that 8.5% of those on degludec experienced a major cardiovascular event and 4.9% had prespecified adjudicated severe hypoglycemia, compared with 9.3% and 6.6% of those on glargine, respectively. The findings, published in The New England Journal of Medicine and presented at the American Diabetes Association's meeting, also revealed a significantly lower fasting plasma glucose level among those who received degludec than those in the glargine group.
A study in PLOS ONE showed no significant differences in relative insulin response from baseline between type 2 diabetes patients who received 2 mg of tesamorelin and those on placebo. Researchers looked at 53 diabetes patients and found that those on tesamorelin had a significant drop in non-HDL cholesterol and total cholesterol levels, compared with the placebo group, but did not find any significant differences in diabetes control and A1C levels between the two groups.
Australian researchers found that adults with type 2 diabetes who initiated proton pump inhibitor therapy had an increased composite, five-year cardiovascular disease risk score at 2.1 years of follow-up, while those who had an average duration of therapy of at least 12 months had a greater adjusted mean reduction in estimated glomerular filtration rate than those who remained off proton pump inhibitor therapy throughout follow-up. The findings in The Journal of Clinical Endocrinology & Metabolism, based on 1,036 patients, revealed no differences in changes from baseline urinary albumin to creatinine ratio between the groups.
Register for Chicago today! If you are a health care practitioner actively seeking timely, tangible solutions in the field of cardiometabolic disease, this 1-day CMHC Focus on Frontline Education Regional Conference Series offers a high-quality learning experience -- coupled with the potential for networking with like-minded providers and professionals. Earn up to 6.5 CME/CE credits!
When managing clinically complex patients with T2DM, HCPs should consider the efficacy of therapies, the AEs, such as weight gain and hypoglycemia, and patient preferences. But management goes beyond reducing hyperglycemia, as those with T2DM have a higher risk of CVD and atherothrombotic events than non-diabetic patients. This virtual symposium will interweave cases that examine how to individualize goals and therapies based on patient characteristics, comorbid diseases, and priorities. Learn more.