Study links poor medication adherence in diabetes to increased CVD risk | Study: Adults considered fit but fat have higher heart risks | Study ties cancer diagnosis to higher CV events risk
August 16, 2017
Cardiometabolic Health SmartBrief
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Study links poor medication adherence in diabetes to increased CVD risk
UK researchers found that type 2 diabetes patients with poor medication adherence had a higher risk for cardiovascular disease than those with good medication adherence. The findings in Diabetes Care, based on a meta-analysis of eight observational studies involving 318,125 adult diabetes patients, also revealed an association between good medication adherence and reduced risks for all-cause mortality and hospitalization.
Healio (free registration)/Endocrine Today (8/14) 
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Science & Research
Study: Adults considered fit but fat have higher heart risks
Study: Adults considered fit but fat have higher heart risks
(Lisa Maree Williams/Getty Images)
Metabolically healthy adults who were overweight had a 26% higher risk of heart disease, compared with normal-weight adults, while those who were obese had a 28% higher risk, according to a study in the European Heart Journal. People with three or more heart risk factors had twice the likelihood of developing heart disease regardless of their weight, the study found.
HealthDay News (8/14),  CNN (8/14) 
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Study ties cancer diagnosis to higher CV events risk
A study in the Journal of the American College of Cardiology found patients with cancer had greater risks for arterial thromboembolism, heart attack and ischemic stroke six months after their diagnosis, compared with those who did not have cancer. The findings were based on Medicare linked-Surveillance Epidemiology and End Results Program data for 279,719 pairs of patients with cancer and matched controls.
Reuters (8/15),  MedPage Today (free registration) (8/15) 
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More sleep may lower type 2 diabetes risk in youths
Nine- and 10-year-olds who got an additional hour of sleep during weekdays had a 2.9% reduction in insulin resistance, 0.24% lower fasting glucose and 0.19% lower body mass index, which are risk factors for type 2 diabetes, compared with those who got less sleep, UK researchers reported in Pediatrics. However, the findings didn't show a link between sleep duration and HbA1C levels or cardiovascular risk.
The New York Times (free-article access for SmartBrief readers) (8/15),  MedPage Today (free registration) (8/15) 
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Lifestyle & Wellness
Study links diet, weight, age to gestational diabetes risk
A study of South Asian women in CMAJ Open showed a higher risk for gestational diabetes with increased maternal age, a family history of diabetes, higher pre-pregnancy weight and low diet quality. Researcher Sonia Anand said additional studies are needed to see if reducing pre-pregnancy weight and improving diet quality during pregnancy could reduce gestational diabetes rates in this patient population.
Healio (free registration)/Endocrine Today (8/10) 
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Study: A beverage's sweetness can affect metabolic response
Study: A beverage's sweetness can affect metabolic response
(Mario Tama/Getty Images)
Sweet-tasting beverages that are low in calories may spark a greater metabolic response than drinks with more calories, according to a study in Current Biology. Researchers suggested the findings may help explain why some studies have shown links between artificial sweeteners and diabetes.
HealthDay News (8/11) 
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Practice Trends & Technology
Research examines cardiovascular effect of SGLT2 inhibitors on diabetes
A study in The Lancet Diabetes & Endocrinology showed that adults with type 2 diabetes who were new users of SGLT2 inhibitors had reduced risks for severe hypoglycemia, cardiovascular mortality, all-cause mortality, major CV events and hospital events for heart failure, compared with those who used other glucose-lowering drugs. Researchers analyzed data from CVD-REAL Nordic involving 91,320 patients and found no differences for atrial fibrillation, non-fatal myocardial infarction and stroke between the two groups.
Healio (free registration)/Endocrine Today (8/14) 
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Systolic BP treatment similar with prediabetes, normoglycemia
A study in Diabetes Care found that mean systolic blood pressure was 120.7 mmHg for adults with prediabetes and 121.8 mmHg for those with normoglycemia one year after receiving intensive systolic BP treatment, compared with 136.2 mmHg for those with prediabetes and 136.2 mmHg among those with normoglycemia in the standard systolic BP treatment group. The randomized trial included 9,361 adults with a mean age of 67.9.
Healio (free registration)/Endocrine Today (8/10) 
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Study supports lifestyle intervention for diabetes control
Diabetes patients in an intensive aerobic exercise and dietary program saw a greater decrease in average A1C levels than those in a standard care group, and 73.5% required less diabetes medication, compared with 26.4% in the standard care group, according to a study in the Journal of the American Medical Association. Researchers said the improvements in the intervention group did not reach the threshold for equivalence to standard care but were "in a direction consistent with benefit."
Medscape (free registration) (8/15) 
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Cardiometabolic Health Congress News
12th Annual CMHC
12th Annual CMHC
Register for Boston today!
Now in its 12th year, the Cardiometabolic Health Congress is the largest, US-based, multidisciplinary conference focused solely on the management of cardiometabolic risk and the prevention of cardiovascular and metabolic disease. The 3 1/2 day event offers today's busy health care professionals a one-of-a-kind opportunity to learn real-world solutions they can integrate immediately into their clinical practices.
Earn up to 25 CME/CE credits!
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Virtual Symposium: New Developments in Insulin Therapy: Expert Insights in Individualizing Treatment
1.5 Credit Hours
Despite well-established treatment guidelines, many patients with T2DM are not managed optimally and fail to achieve recommended levels of blood glucose control. Delays in initiating insulin, however, are common and may stem from both physician and patient barriers. Negative patient perceptions regarding insulin include complicated dosing regimens, fear of injections, and hypoglycemia. Clinician concerns include hypoglycemia, weight gain, and the misconception that elevated insulin increases cardiovascular risks. Learn more.
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