FDA says don't use OTC teething products that contain benzocaine | Excess weight gain in adolescence may up bowel cancer risk in overweight boys | Sustained vitamin D supplementation reduced wheezing in black preemies
Over-the-counter teething products that contain benzocaine pose a "serious risk to infants and children" and offer no benefit, according to an FDA warning. Teething gels, sprays, ointments, solutions and lozenges that contain benzocaine could cause the fatal blood condition methemoglobinemia, the FDA said, and the agency is asking manufacturers to stop marketing the products for pediatric use.
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Overweight boys who had above-average weight gain in adolescence were 48% more likely to develop bowel cancer as adults, compared with those who had healthy weight at ages 8 and 20, according to a Swedish study to be presented at the European Congress on Obesity. However, researchers found no increased bowel cancer risk among overweight boys without excessive weight gain during puberty.
A study in the Journal of the American Medical Association showed that 31.1% of black preterm infants given sustained vitamin D supplementation had recurrent wheezing at age 12 months, compared with 41.8% of those who received diet-limited supplementation. The findings also showed that upper and lower respiratory infections were the most common adverse events and were less prevalent among those in the sustained vitamin D supplementation group.
A study of 100 simulated NICU networks of 52 infants showed as the frequency of surveillance for methicillin-resistant Staphylococcus aureus increased from four weeks to one week, the mean number of MRSA-colonized infants decreased from 2.9 per episode to 0.6 per episode. The study in the Journal of Hospital Infection also showed a drop in the mean duration of MRSA colonization from 307 hours to 61 hours, though researchers noted reduced availability of isolation rooms.
Researchers found that children with chronic hepatitis B and immune-tolerant characteristics who received interferon therapy followed with lamivudine had significantly better rates of undetectable serum HBV DNA, HBV surface antigen loss and HBV e-antigen seroconversion, compared with those in the control group. The findings in the Journal of Hepatology showed similar median alanine aminotransferase levels between both groups, and no serious adverse events were reported.
The FDA gave Zimmer Biomet clearance to market its 3D-printed Zyston Strut Open Titanium Interbody Spacer System, a family of lumbar cages designed for improving the interbody spacer's graft capacity, visualization and strength during spinal fusion procedures. The system also includes surgical tools for facilitating implant insertion, manipulation and removal.
A Better Sleep Council poll found that women are more sleep deprived than men despite 84% of females indicating the importance of sleep to their health. Women were more likely to let children and pets share the bed, which was a barrier to uninterrupted sleep, and also more likely to have difficulty falling asleep or staying asleep.
A Congressional Budget Office analysis estimates that health insurance premiums in Affordable Care Act markets will increase an average of 15% next year as a result of the repeal of the ACA's individual mandate penalty, rising health care costs and the administration's decision to halt cost-sharing reduction payments to insurers. The number of uninsured people will increase by 3 million between 2018 and 2019, but ACA marketplaces are expected to be stable in most parts of the US over the next 10 years, according to the report.
Covered California Chief Medical Officer Lance Lang said health plans have been told that by the end of 2019 all hospitals included in their networks should meet specified safety and quality metrics or risk being excluded from the "in-network" designation in the state's health insurance marketplace. Hospitals will be assessed on unnecessary cesarean sections, opioid prescribing, and imaging utilization in diagnosing and treating lower back pain.
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