Cardiorespiratory fitness and mortality | A mouse model of antepartum stillbirth | How do experiences with weight stigma vary by race?
October 19, 2017
AJM: From the publisher of The American Journal of Medicine
News for physicians working in clinical settings
Top News
Cardiorespiratory fitness and mortality
Because most people in developed nations are performing less physical activity today than in the past, strong encouragement and recommendations for improving cardiorespiratory fitness through regular exercise should be applied aggressively to both black and white patients. FIT Project research indicates that all-cause mortality risk is reduced by improving exercise capacity in both blacks and whites.
The American Journal of Medicine (10/2017) 
CME Interview Series: Cystic Fibrosis
Dr. John P. Clancy interviews eight experts in the cystic fibrosis field. The individual modules will focus on different areas of CF care, ranging from newborn screening to long-term real world efficacy and safety data. Each module is worth approximately 0.5 CME/CNE credits. Click here to begin this activity.
Clinical Updates
A mouse model of antepartum stillbirth
In a mouse model of antepartum stillbirth, deficits in placental function result in fetal growth restriction and hypoxic organ injury.
American Journal of Obstetrics & Gynecology (10/2017) 
How do experiences with weight stigma vary by race?
This study investigated health-related coping responses to weight stigma across racial groups. Results showed weight stigma is present across racial groups, but groups internalize and cope with stigma in different ways. Women reported higher weight bias internalization than men, and black men and women reported less weight bias internalization than white men and women. Compared with white women, black women were less likely and Hispanic women were more likely to use disordered eating to cope with stigma. Black men were more likely than white men to cope with stigma by eating.
American Journal of Preventive Medicine (10/2017) 
Management of angioedema in patients with acquired C1-inhibitor deficiency
The prevalence and treatment of acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE) is not well delineated. The authors report on 77 patients followed at the Angioedema Center, Milan (from 1976-2015). Patients had to have recurrent angioedema without urticaria, decreased C1-INH antigen levels and/or functional activity, onset after age 40 years, and no family history of C1-INH deficiency. They compared demographic and treatment characteristics of these patients to ones with hereditary angioedema. The incidence of C1-INH-AAE was 1 for every 8.8 patients with hereditary forms of the disorder. Treatments approved for the hereditary forms were effective, although with some differences.
The Journal of Allergy and Clinical Immunology: In Practice (10/2017) 
Sleep-disordered breathing in obese patients
A high prevalence of previously unrecognized sleep-disordered breathing was found in obese patients admitted to medical services in the hospital. Screening can be effective in identifying these patients. Early intervention and compliance with positive airway pressure therapy is associated with long-term survival; patients who were adherent to positive airway pressure therapy in the first 3 months had improved survival compared with those who were nonadherent.
The American Journal of Medicine (10/2017) 
The transition to adult care for HIV-positive youths
Extant research suggests that adolescent clinics are primarily responsible for preparing youths to transition to adult care, yet the role of the adult clinic in HIV transition has been largely ignored. Results suggest that adult and adolescent clinic involvement is essential to provide coordinated care during HIV-related health care transition.
Journal of Adolescent Health (10/2017) 
The impact of ACOG guidelines on chlamydia testing
Although chlamydia test rates are increasing among sexually active women aged 15 years to 25 years from 2005 to 2014, the slower growth in the chlamydia testing rate after 2009 may relate to the change in the Pap testing guidelines.
Journal of Adolescent Health (10/2017) 
Continuing Medical Education
New CME: Therapeutic Advances in Dyslipidemia from ESC 2017
New CME: Therapeutic Advances in Dyslipidemia from ESC 2017
This CME program will feature content presented at the European Society of Cardiology (ESC) Congress 2017 in Barcelona, Spain. Expert faculty analyze recent therapeutic advances in the treatment and management of patients with dyslipidemia, as well as the role of PCSK9 inhibitors in lowering LDL-C and reducing cardiovascular risk in those patients. Upon completion, learners will have a better grasp of evolving science in the field of dyslipidemia as it relates to improving outcomes and quality of life in clinical practice. Begin this activity!
Medical News
Study: 12% of men, 3% of women have oral HPV
A study in the Annals of Internal Medicine showed almost 12% of men and some 3% of women were infected with oral human papillomavirus. Oral HPV has been linked to cancer of the head, neck and throat.
HealthDay News (10/16) 
Men get AFib 10 years earlier than women, weight is a risk factor
An American Heart Association report published in the journal Circulation found men were more likely to develop atrial fibrillation after age 50 and women were more likely to see symptoms after age 60, and body mass index was a significant risk factor, especially for men.
Cardiovascular Business online (10/16) 
Study: Commercial weight management program tied to diabetes prevention
Patients with non-diabetic hyperglycemia who participated in a diabetes prevention program delivered by a commercial weight management provider experienced a mean A1C reduction of 2.84 mmol/mol and a mean weight reduction in body mass index of 3.2 kg/m2 at 12 months, according to a study in BMJ Open Diabetes Research & Care. UK researchers used a cohort of 166 patients and found that 38% of the participants returned to normoglycemia, while 3% progressed to type 2 diabetes at 12 months.
Physician's Briefing/HealthDay News (10/17) 
Business Practice News
Communication technique improves patient satisfaction scores
A study in the journal Family Medicine found the psychosocial BATHE intervention, which stands for background, affect, trouble, handling and empathy, increases hospital inpatient satisfaction scores. The technique lets patients share psychological or life problems with clinicians, and data showed patients who participated gave their physicians an average score of 4.77, compared with a 4.0 score given by patients receiving standard care.
HealthLeaders Media (10/16) 
Free tool helps physicians improve their diagnostic skills
The Society to Improve Diagnosis in Medicine released its Assessment of Reasoning Tool, a free resource to help physicians improve diagnostic and clinical reasoning skills. The tool is available on the society's website and comes with five short videos that focus on issues such as understanding the diagnostic process, factors contributing to diagnostic errors and working with patients and families in the decision-making process.
Medscape (free registration) (10/13) 
Patient's Perspective
Study links excessive exercise with CAC development in white men
A study published in Mayo Clinic Proceedings found white men who got three times the recommended 150 minutes of exercise per week over 25 years had a higher risk of developing coronary artery calcification by middle age, compared with black men and men who worked out less. Researchers said more studies are needed on the biological mechanisms involved in CAC, which is a risk factor for heart disease.
Daily News (New York) (10/17) 
Make no little plans; they have no magic to stir men's blood. ... Make big plans; aim high in hope and work.
Daniel Burnham,
architect and urban designer
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