Study: Hookworm therapy may benefit celiac disease patients | CRC test may help late-stage cancer patients | Study finds low neoplasia rate in asymptomatic Lynch syndrome
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September 29, 2014
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Clinical Updates
Study: Hookworm therapy may benefit celiac disease patients
A small trial of celiac disease patients treated with helminthic therapy were better able to tolerate gluten foods without triggering symptoms, Australian researchers reported in The Journal of Allergy and Clinical Immunology. The study, which included 12 celiac disease patients who were followed for up to one year, found the eight who completed the trial were able to raise their gluten tolerance by a factor of 60. (9/26)
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CRC test may help late-stage cancer patients
A U.K. study found late-stage colorectal cancer diagnosed through fecal occult blood testing was linked to better survival than when the cancer was diagnosed after symptoms were evident following a negative fecal occult blood test. The University of Leeds and Durham University screening study did not find survival and mortality benefits for early-stage cancer patients. Oncology Nurse Advisor online (9/24)
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Study finds low neoplasia rate in asymptomatic Lynch syndrome
A video capsule endoscopy study found a 1.5% rate of small-bowel neoplasia among asymptomatic Lynch syndrome patients, according to researchers in the Netherlands. Partly due to limited visualization options, screening has not been recommended for these patients, and this study suggests it may not be warranted, researchers said. Medscape (free registration) (9/25)
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HCV-associated lymphoma linked to mild liver disease in study
Hepatitis C patients diagnosed with HCV-associated B-cell non-Hodgkin's lymphoma may also show signs of mild liver disease, researchers reported at an HCV conference. The study team said HCV patients should get early antiviral therapy because few patients who achieved a sustained virologic response developed the cancer. Healio (free registration)/HCV Next (9/25)
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ACG note: AJG Video of the Month
Did you see the video in this month’s issue of the AJG? Watch it now.
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Legal & Regulatory
Drugmaker gains FDA nod for new adalimumab indication
AbbVie has obtained federal approval for a new indication for its adalimumab drug. The medication may be used in Crohn's disease patients aged 6 and older who are nonresponsive to other treatments. Drug Store News (9/25)
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Practice News
Reducing colonoscopy fees could hurt access, usage, report says
A physician's colonoscopy fee accounts for about 20% of the total procedure cost, and reducing it could negatively affect access to and use of the cancer screening, according to a report by AJMC Managed Markets Network. Medicare reduced physician payments for upper endoscopy procedures and colonoscopy in 2014 and doctors may see additional cuts next year. (9/24)
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Report examines safety, quality framework at medical practices
An Agency for Healthcare Research and Quality study found 86% of survey respondents said their medical practice has a strong teamwork culture, while the same proportion said their organization takes steps to track and follow up with patients. Eight in 10 respondents indicated positive perceptions of their practice's approach to patient safety and care quality, but many indicated productivity is more highly valued than quality. (9/26)
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Business & Market Trends
Data analytics can help researchers zero in on clinical targets
Data analytics software may help reduce costs by allowing researchers to better target treatments, technology experts said at the Health 2.0 Annual Fall Conference. John Wolpert of IBM said finding just one good clinical target can take a year, but Baylor University used IBM's Watson computer to analyze millions of colon cancer articles and found six targets in one attempt. Medscape (free registration) (9/26)
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Patient's Perspective
Younger college grads more likely to trust questionable health data
Recent data showed younger patients with at least four years of college were more likely to trust questionable online health information than their older counterparts with no more than a high-school education. Researchers also found women and individuals with health trouble were most likely to seek anecdotal medical information. The findings are slated for presentation at the Human Factors and Ergonomics Society meeting. HealthDay News (9/24)
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ACG News
Application process now open for WGO 2015 Train the Trainers Workshop in Taipei, Taiwan
If you are an educator in the fields of gastroenterology, hepatology, endoscopy or GI surgery, submit your CV today for a chance to participate in WGO's Train the Trainers (TTT) Workshop taking place April 13-16, 2015 in Taipei, Taiwan (attendees must arrive on April 12 and will depart on April 17). Applicants must be fluent in English. The ACG will nominate two members to participate in the TTT Taipei program. If you are interested in applying, send your CV to Maria Susano at the ACG office at The deadline to apply is Friday, October 10.
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Pearls and Pitfalls of Routine IBD Management: Case Studies
Hear leading IBD experts Edward V. Loftus, Jr., M.D., FACG, Uma Mahadevan, M.D., and Miguel Regueiro, M.D., FACG, discuss the newly diagnosed IBD patient, the medically refractory IBD patient, and the post-operative IBD patient, when you attend the simultaneous symposium, Pearls and Pitfalls of Routine IBD Management: Case Studies, to be offered on Tuesday, Oct. 21, during the Annual Scientific Meeting. The Annual Scientific Meeting will take place Monday, Oct. 20, through Wednesday, Oct. 22. Registration is now open. Review the entire agenda. Learn more about ACG 2014 at
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