Liver stiffness predicts liver-related events in chronic HBV | Study: Antibiotics fail to reduce infection risk after gallbladder removal | Antiretroviral therapy cleared HCV in some HIV-infected patients
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July 9, 2014
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Clinical Updates
Liver stiffness predicts liver-related events in chronic HBV
Patients infected with chronic hepatitis B virus who had a liver stiffness value of 8 kPa or more may be more likely to have a liver-related event after achieving complete virologic response with antiviral therapy, according to a study published in The American Journal of Gastroenterology. The researchers recommend tailoring surveillance strategies based on LS values at CVR. Read the abstract. Healio (free registration) (7/7)
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Study: Antibiotics fail to reduce infection risk after gallbladder removal
A French study found that the risk of infection following gallbladder removal is not reduced by postoperative antibiotics. Among patients who did not receive postoperative antibiotics, 17% developed an infection while 15% of those who did receive the post-op dose developed infections. The lack of a placebo in the nontreatment group and absence of blinding in the design could have "decreased the reliability of our evaluation of the primary outcome and the groups' comparability," the researchers noted. MedPage Today (free registration) (7/8), HealthDay News (7/8)
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Antiretroviral therapy cleared HCV in some HIV-infected patients
Three patients with the IL28B CC genotype infected with both HIV and hepatitis C virus spontaneously became negative for HCV RNA after undergoing antiretroviral therapy, a Swedish study showed. "We argue that HIV/HCV coinfected patients probably should commence ART prior to HCV treatment, in particular if they have the IL28B CC gene, since it might occasionally induce spontaneous HCV clearance of a chronic HCV infection," the researchers wrote. Healio (free registration) (7/4)
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Low vitamin D levels linked to cancer risk in IBD patients
Low vitamin D levels were associated with an increased risk for metastatic and nonmetastatic cancers, and especially for colorectal cancer, in patients with inflammatory bowel disease, researchers at Massachusetts General Hospital found. About two-thirds of IBD patients have low vitamin D levels, and though the study had limitations, it showed that vitamin D may offer long-term health benefits for IBD patients, gastroenterologist Ashwin Ananthakrishnan writes. MedPage Today (free registration) (7/8)
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Study ties HCV to heightened risk of end-stage renal disease
A death-adjusted competing risk model found an association between hepatitis C virus infection and an elevated risk for developing end-stage renal disease in chronic kidney disease patients. The researchers also found that HCV infection was an independent risk factor for ESRD. Healio (free registration) (7/2)
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Legal & Regulatory
HHS allocates $100M for health organizations
HHS is set to provide $100 million in grants next year for the expansion of 150 new local health organizations that provide medical care and education. The announcement came a month after the agency announced $300 million in funding for expanded staff, schedules and services at community health centers. The Hill (7/8)
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Practice News
ACG partners in Value of Colonoscopy initiative
The ACG along with AGA and ASGE have partnered on a new initiative known as The Value of Colonoscopy: Saving Lives Through Expert Care, which stresses the importance of colonoscopy to patients and policymakers and seeks to boost care and affordability while supporting community health. BeckersASC.com (7/8)
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Working group releases tools for meeting new accreditation standards
The ACG worked with other gastroenterology and hepatology societies to develop toolboxes for 13 core tasks under the new Accreditation Council for Graduate Medical Education Internal Medicine Subspecialty Reporting Milestones requirements. The tools are offered to educators and trainees to enhance their current approach while working toward meeting the new requirements of the Next Accreditation System. Healio (free registration) (7/8)
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Business & Market Trends
Electronic reimbursement through credit cards may carry fees
Insurers are transitioning to an electronic payment system that could reduce administrative burdens by helping providers match bills to individual patients and trace each patient billing transaction. However, some payers are sending payments through a virtual credit card, which deducts a fee of 1% to 4%, and providers can lose key information in virtual credit card transactions that is preserved in electronic fund transfers. HealthLeaders Media (7/7)
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Patient's Perspective
Data show increased inactivity in American men, women
A Stanford University study showed 52% of U.S. women and 43% of U.S. men reported no physical activity in 2010, a significant increase from 19% and 11%, respectively, in 1988. However, caloric consumption remained the same between 1988 and 2010, suggesting that inactivity may be a critical factor in the rise in obesity rates. KQED.org/State of Health blog (7/7)
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ACG News
AJG Podcast with Dr. Naga P. Chalasani and Dr. Herbert L. Bonkovsky discusses the new ACG clinical guideline for DILI
Naga P. Chalasani, M.D., FACG, and Herbert L. Bonkovsky, M.D., FACG, co-authors of the new ACG Clinical Guideline on drug-induced liver injury (DILI) talks with AJG Co-Editor Dr. William D. Chey about the definition of DILI and its different subtypes, risk factors for the disorder, the drug classes that pose the greatest risk of liver injury, and the essentials of clinical work-up for DILI patients, including when to perform a liver biopsy. Special note is paid to herbal and dietary supplements, which are largely unregulated and have caused increasing harm to patients over the past few years. Listen to the podcast. Read the article.
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Update in Hepatology
Applying recent ACG guidelines to practice, hear experts analyze evidence-based evaluation of liver lesions and offer strategies to diagnose and manage drug-induced liver disease, plus learn about new advances and therapeutic options for patients with hepatitis C when you attend the simultaneous symposium Update in Hepatology. Offered during the 2014 Annual Postgraduate Course, October 18-19 at the Pennsylvania Convention Center in Philadelphia, the session will be moderated by Mitchell L. Shiffman, M.D., FACG, with K. Rajender Reddy, M.D., FACG and Paul Y. Kwo, M.D., FACG also presenting. Other liver topics covered during the Annual Postgraduate Course include three optional Learning Luncheons: Liver Transplant Management in the Community, Treatment Strategies for the Resistant Patient with Hepatitis B, and Update in NASH. Registration for the ACG 2014 Annual Postgraduate Course is open. Learn more about ACG 2014 and register now.
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SmartQuote
Failure is simply the opportunity to begin again, this time more intelligently."
-- Henry Ford,
American industrialist
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