Study links bacteria to colon polyps, cancer | More frequent vedolizumab dosing may help IBD patients regain response | Analysis: Garlic supplements, allium vegetables fail to lower CRC risk
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December 24, 2014
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Clinical Updates
Study links bacteria to colon polyps, cancer
A Johns Hopkins University study has found that most colon polyps and cancers, particularly those on the right side of the colon, are coated in bacterial biofilms. The biofilms, which may cause inflammation and some bowel diseases, were found on 89% of tumors extracted from the right side of the colon in biopsies from over 100 people. The findings may help to create a noninvasive test to predict whether a patient is at risk of developing colon cancer, researchers said. HealthDay News (12/19)
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More frequent vedolizumab dosing may help IBD patients regain response
Patients with inflammatory bowel disease who have stopped responding to treatment with vedolizumab may benefit from more frequent doses of the drug, according to researchers at the Icahn School of Medicine at Mount Sinai. The study found that administering the drug every four weeks to patients who stopped responding to maintenance dosing every eight weeks helped some regain response or achieve remission. Healio (free registration)/Gastroenterology (12/18)
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Analysis: Garlic supplements, allium vegetables fail to lower CRC risk
Researchers in China who analyzed 13 long-term studies aimed at finding links between colorectal cancer risk and garlic supplements or allium vegetable consumption concluded that neither reduces patients' risk of getting the disease. In fact, the data show, taking garlic supplements was linked to an elevated risk, and high allium vegetable intake appeared to be associated with a slightly higher risk of colon cancer for female patients. The researchers called for further studies of the possible negative effects of garlic supplements. Healio (free registration)/Gastroenterology (12/23)
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HCC patients with high AKR1B10 protein expression survive longer, study shows
High aldo-keto reductase 1B10 protein expression in patients with hepatocellular carcinoma appears to be correlated with longer survival and recurrence-free rates, researchers in Korea have found. The results of the study indicate that high expression "might be a clinically useful predictive marker for good prognosis of HCC after curative hepatectomy," researchers said. Healio (free registration) (12/18)
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Legal & Regulatory
Medicaid rolls expand even where eligibility did not
The number of people on Medicaid grew 12.4% in North Carolina, 12.9% in Georgia and 13.4% in Idaho since the Affordable Care Act exchanges opened, though none of those states expanded eligibility. Medicaid enrollment is up 6.8% overall in states that did not expand eligibility, CMS data show. The New York Times (tiered subscription model)/The Upshot blog (12/18)
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Senate panel suggests tools to boost generics use in Medicare Part D
A bipartisan report from the Senate Special Committee on Aging suggests ways to increase generic-drug utilization under Medicare Part D, including educating subscribers and physicians on the value and safety of generic drugs, boosting incentives to drug plans that increase generics utilization, and stepping up probes of questionable billing practices by pharmacies designed to interfere with generics utilization. The Daily Star-Journal (Warrensburg, Mo.)/U.S. Senate Special Committee on Aging (12/16)
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Practice News
Gastroenterologists look back on the year's top issues
As 2014 draws to a close, four gastroenterologists share what they see as the most important developments in the field over the course of the year. Their picks include FDA approval of the noninvasive colorectal cancer screening test Cologuard, developments in electronic medical records, delays in the implementation of the ICD-10 system and creating a voice for independent gastroenterology groups. BeckersASC.com (12/19)
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Business & Market Trends
Digital health tools popular among U.S. caregivers
A Parks Associates report showed more than 40% of U.S. caregivers in broadband households used digital health technology in their duties, and 8% of that group used online tools to bolster care coordination. Current and future caregivers also expressed interest in using technologies such as electronic sensors, home monitoring security systems and GPS devices. Healthcare Informatics online (12/22)
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Patient's Perspective
Study shows gap between EHRs, self-reporting of race, language preferences
A study in the Journal of General Internal Medicine revealed that while 27% of patients labeled themselves as black and 19.6% reported Hispanic ethnicity, EHRs identified only 16.6% of Hispanics and 20.4% of blacks. Data also showed EHRs marked English as the primary language in some respondents who took the survey in Spanish. BeckersHospitalReview.com (12/22)
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ACG News
The College wishes everyone a happy and healthy holiday with family and friends.
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SmartQuote
You've got to go out on a limb sometimes because that's where the fruit is."
-- Will Rogers,
American performer and humorist
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