Study: ESG patients have fewer adverse events but less weight loss | Study compares efficacy of weight-loss surgical procedures in severe obesity | Obesity tied to heritable neurobehavioral factors
September 10, 2018
Bariatric SmartBrief
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Therapies & Devices
Study: ESG patients have fewer adverse events but less weight loss
Endoscopic sleeve gastroplasty patients did not lose as much weight in the six months after the procedure as those who underwent laparoscopic sleeve gastrectomy, but ESG patients had fewer adverse effects, ABE Advisory Board member Dr. Vivek Kumbhari, director of endoscopy at Johns Hopkins Bayview Medical Center, and colleagues reported in Gastrointestinal Endoscopy. None of the ESG patients had an adverse reaction while hospitalized after the surgery, compared with four LSG patients who did.
Healio (free registration) (8/28) 
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Study compares efficacy of weight-loss surgical procedures in severe obesity
A study published in the journal Surgery showed that people with severe obesity lost an average of 30% of their weight with Roux-en-Y gastric bypass, compared with 24% for those who underwent a sleeve gastrectomy procedure. Researchers recruited 59 patients and found an association between both types of surgery and reduced obesity-related health problems, such as diabetes, high cholesterol levels and high blood pressure.
Reuters (9/6) 
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Health News & Research
Obesity tied to heritable neurobehavioral factors
A higher body mass index is linked to differences in brain structure and mental factors such as the ability to delay gratification and reduced cognitive flexibility, researchers reported in the Proceedings of the National Academy of Sciences. "Interventions shouldn't just focus on diet, but also acknowledge the neurobehavioural profile that obesity is genetically intertwined with," said lead author Uku Vainik of the Montreal Neurological Institute and Hospital.
Genetic Engineering & Biotechnology News (8/29),  PNAS (8/28) 
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Research compares efficacy of semaglutide, liraglutide in weight loss in obesity
Individuals with a body mass index of more than 30 kg/m2 who received once-daily semaglutide had mean weight reductions ranging from 6.0% to 13.8% of baseline weight at 52 weeks, compared with a 7.8% and a 2.3% reduction in baseline weight among those on liraglutide and placebo, respectively, researchers reported in The Lancet. There was also a significantly greater weight loss among patients who increased their semaglutide dose every four weeks than those who took 3.0 mg of liraglutide over 52 weeks.
Endocrinology Advisor (9/5) 
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Research finds obesity pharmacotherapy effective for weight loss
A study presented at the 2018 AGA James W. Freston Conference showed that patients with obesity who were prescribed a combination of topiramate ER and phentermine, a combination of naltrexone and bupropion SR, or liraglutide, lorcaserin, metformin, phentermine or topiramate had a total body weight loss of 4.8 kg at three months and a TBWL of 10.3% after one year. Researchers analyzed 178 patients, mean age of 47.6, and found that 65% and 44% lost more than 5% and more than 10% of their total body weight with pharmacotherapy, respectively.
Healio (free registration)/Gastroenterology (8/31) 
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Intrahepatic cholangiocarcinoma risk tied to obesity, diabetes, study shows
Researchers analyzed data from 13 US-based cohort studies and reviewed 14 published studies and found that obesity and self-reported diabetes were associated with a 62% and an 81% increased risk for intrahepatic cholangiocarcinoma, compared with those with a normal body mass index and those without diabetes, respectively. The findings in The American Journal of Gastroenterology showed that in prospective studies, individuals with a diabetes history had a 53% increased ICC risk, while obesity was tied to a 49% increased ICC risk in the systematic review.
Healio (free registration) (9/5) 
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Nutrition, Wellness & Lifestyle Support
Survey examines language preferences among people with obesity
A survey of people seeking bariatric surgery found 75% preferred the term "person with obesity" over "obese person," researchers reported in JAMA Surgery. The study found respondents preferred the terms "person with elevated BMI" and "person with obesity" for those with a BMI of 30 or greater and "class III obesity" and "severe BMI" for people with a BMI of 40 or greater.
MedPage Today (free registration) (9/5) 
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WHO: 1.4B people don't achieve recommended physical activity levels
A study conducted by the World Health Organization and published in The Lancet Global Health revealed that 1.4 billion people, or more than 25% of the world's adults, do not meet the recommended levels of physical activity of at least 150 minutes of moderate exercise per week, or 75 minutes of vigorous exercise per week, putting them at an increased risk for type 2 diabetes, cardiovascular disease, cancers and dementia. Researchers found the highest rates of insufficient physical activity in 2016 among adults in American Samoa, Iraq, Kuwait and Saudi Arabia, while around 40% of adults in the US, 36% in the UK and 14% in China did not exercise frequently enough to stay healthy.
Reuters (9/4) 
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The Business of Health Care
Report: Health care will remain a top cyberattack target
The high value of patient data would make health care one of the most targeted sectors by cyberattackers, according to a survey of 1,312 senior executives by Marsh & McLennan and Microsoft. In the health care sector, half of respondents said they were not confident about their organization's ability to manage and recover from a cyberattack.
Health IT Security (9/7) 
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Survey examines patients' willingness to share health data
A Rock Health survey of nearly 4,000 adults in the US revealed that 86% are willing to share their health data, such as medical records, physical data or genetic information, with a physician, while 58% are willing to share their health information with a health insurance company and 52% with a pharmacy. Eighty-seven percent reported being "confident" or "somewhat confident" in physicians' data security practices, compared with 68% for pharmacies and 60% for health insurance companies.
Becker's Health IT & CIO Report (9/4) 
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The key is not to prioritize what's on your schedule, but to schedule your priorities.
Stephen Covey,
writer and educator
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