MTF Biologics master tissue technician Luis Lora shares insights about his work preparing grafts such as cartilage, bone, ligaments and skin for use by health care professionals treating patients. "We clean the tissue and sometimes treat it with chemicals that remove the cells -- a process called decellularization. We also have it tested to make sure it can't transmit any infection to the person who receives it," Lora said.
The Miami-Dade County Mosquito Control and Habitat Management Division released Wolbachia bacteria-infected, nonbiting biotech male mosquitoes hoping to prevent mosquito-borne virus outbreaks such as Zika. The biotech mosquito's Wolbachia infection will prevent any offspring produced when it mates with wild female mosquitoes from surviving to adulthood, thus reducing the wild mosquito population.
An analysis of genomic data from 50 postmortem tissue samples from five patients found the spleen is "a prime candidate for an HIV tissue sanctuary and a therapeutic target in HIV cure research," according to a study in the journal AIDS Research and Human Retroviruses.
Children who underwent living donor liver transplantation had a 47% reduced risk of post-transplant acute cellular rejection and a significantly lower likelihood of chronic rejection, compared with those who received deceased donor liver transplantation, according to a study in the journal Transplantation. Researchers also found a significantly higher likelihood of graft survival and monotherapy immunosuppression after three years, as well as a 71% lower graft loss risk, among LDLT recipients.
Numerous studies are underway to determine how gene therapy and the use of gene-editing tools can possibly cure HIV by using altered cells to decimate the virus and reduce the number of cells in reservoirs where HIV stays hidden in a dormant state. One such study is being conducted by Dr. John Zaia of City of Hope research center in California, which tweaks blood stem cells to disable a gene to allow the cells to resist HIV.
Women older than 65 who had direct-to-implant breast reconstruction had shorter drain duration, fewer hospital readmissions and postoperative visits, and shorter hospital stays than women who had tissue expander/implant reconstruction, despite the younger average age in the comparison cohort. The study, published in Plastic and Reconstructive Surgery, also found similar complication and failure rates between the two cohorts, suggesting that direct-to-implant reconstruction is a safe option for older women.