Childhood abdominal radiation tied to pregnancy risks later | Infection increases stroke risk for women with preeclampsia | Research links GI syndrome to cirrhosis, portal hypertension
April 27, 2017
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Childhood abdominal radiation tied to pregnancy risks later
Women who survived childhood cancer after receiving abdominal radiation therapy had a higher risk of gestational diabetes and anemia during pregnancy compared with survivors who received other treatments. Researchers wrote in the Journal of the National Cancer Institute that women who survived childhood cancer but didn't have radiation did not appear to have greater risk of labor complications compared with women who never had cancer.
Reuters (4/26) 
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Infection increases stroke risk for women with preeclampsia
A population-based study found women with preeclampsia who develop infections, particularly urinary tract infections, had a threefold increased risk of stroke, researchers told the American Academy of Neurology's annual meeting. Bleeding disorders, prothrombotic states and chronic hypertension also were tied to increased risk of stroke.
NeurologyAdvisor.com (4/25),  Medscape (free registration) (4/25) 
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Research links GI syndrome to cirrhosis, portal hypertension
Researchers linked cirrhosis and portal hypertension with what they called "acute on chronic GI bleeding" syndrome, according to a study in the Journal of Investigative Medicine. The study found patients with acute on chronic bleeding had lower 30-day mortality rates than those with only acute bleeding.
Healio (free registration)/Gastroenterology (4/24) 
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Obesity tied to increased type 2 diabetes risk in children, study finds
Obesity tied to increased type 2 diabetes risk in children, study finds
(John Moore/Getty Images)
A study in the Journal of the Endocrine Society showed that children with obesity had an almost four times increased risk of developing incident type 2 diabetes before reaching adulthood, compared with those with a normal body mass index. UK researchers used a cohort of 369,361 children ages 2 to 15 and found a 1.6-fold increase in diabetes risk for every 1 standard deviation increase in BMI z score.
Healio (free registration)/Endocrine Today (4/25) 
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Pharmaceutical News
Prenatal tenofovir may reduce hepatitis B transmission risk
Children whose mothers with hepatitis B received the antiviral drug tenofovir in the second or third trimester of pregnancy were 77% less likely to have virus transmission, compared with those whose mothers didn't, South Korean researchers reported in the journal Alimentary Pharmacology & Therapeutics. The findings were based on an analysis of 10 studies involving 733 women.
United Press International (4/24) 
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Data indicate bezlotoxumab may reduce recurrent C. diff
An analysis of the MODIFY trials indicated one infusion of bezlotoxumab reduced the incidence of recurrent Clostridium difficile infection in inflammatory bowel disease patients, researchers reported at the European Congress of Clinical Microbiology and Infectious Diseases. Researchers cautioned, however, that the study cohort was small and more data are needed.
Healio (free registration)/Gastroenterology (4/24) 
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Emerging Trends, Products and Technologies
WHO: Hepatitis a major global health threat
The rise in the number of deaths caused by hepatitis makes the disease a global health threat on the level of tuberculosis and HIV, according to a World Health Organization report. The data, presented at the International Liver Congress, showed a 22% increase in deaths resulting from chronic hepatitis B and C from 2000 to 2015, with 328 million people infected with viral hepatitis in 2015.
MedPage Today (free registration) (4/21) 
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CDC: Fewer US adults are unaware they have hypertension
A CDC report said data from 2011 to 2014 showed 15.9% of US adults with hypertension were unaware that they had it, compared with 29.5% from 1999 to 2002, a decrease of 46%. More men than women and more younger people than older adults were unaware they had hypertension, the report found.
Medscape (free registration) (4/26) 
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Study examines trends in US gallbladder cancer
Women had significantly higher rates of gallbladder cancer from 1973 to 2009, compared with men, according to a study in Cancer Medicine. The findings, based on 18,124 cases of gallbladder cancer from the Surveillance, Epidemiology, and End Results Program database, showed survival rates were higher among women and Asian-Pacific Islanders than men and other racial groups, and the highest among patients receiving both radiation and surgery.
BeckersASC.com (4/26) 
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Health info Videos – “FDA Drug Info Rounds”
"Definition of a Drug" - Whether a product is regulated as a drug, a cosmetic, or both under the law is determined by a product's intended use. FDA pharmacists discuss the key differences between a drug and a cosmetic. View the free video now!
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Health Policy and Legislative News
Details of GOP health care amendment emerge
Details of GOP health care amendment emerge.
(Carl Court/Getty Images)
An amendment to Republican health care legislation proposes letting states seek waivers to opt out of the Affordable Care Act's community rating requirements, but they would have to have a high-risk pool available for consumers with pre-existing conditions, according to legislative text circulated by House Republicans. States could also seek waivers to opt out of essential health benefits requirements, and states applying for waivers would only need to meet one of numerous possible criteria, such as increasing choice of plans or reducing premiums.
The Hill (4/25),  Politico (4/25) 
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AANP News
AANP Data Collection Program at conference -- Deadline extended
Each year, a limited number of spots are made available at the AANP National Conference for researchers interested in collecting data among a sample of over 5,000 conference attendees, or for conducting focus groups. Don't miss your opportunity to gain unparalleled access to the NP workforce and recruit NPs into your study. Data collection tables are set up in a high traffic area within the conference venue, and focus groups are arranged in private meeting rooms. All application materials must be received by April 30. Apply today.
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Should NP Student Didactic Content be "Front-Loaded"?
In the "Point/Counterpoint" section of the April JNP, Rod Hicks says front-loading didactic material and following with intensive clinical education should become standard and may contribute to the safe delivery of care. Cathleen Crowley-Koschnitzki, however, says students, preceptors, and faculty benefit from the integration of clinical experience while simultaneously learning course content. Read their discussion.
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