Prediabetes tied to CV, renal disease risks, study finds | Ambulatory BP predicts mortality more accurately than clinical BP, study finds | Study assesses link between asthma, lung function in teens born preterm
April 19, 2018
AANP SmartBrief
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Prediabetes tied to CV, renal disease risks, study finds
A study in The Lancet Diabetes & Endocrinology showed that 7.7% of individuals with prediabetes had albuminuria, 51.2% had dyslipidemia, 4.6% showed reduced estimated glomerular filtration rate and 36.6% had hypertension, and the 10-year cardiovascular event risk was between 5% and 7%. Researchers evaluated data from four US National Health and Nutrition Examination Surveys involving 27,971 adults, ages 20 and older, and found greater improvements in all treatments for CV and renal risks, except for smoking, among individuals with diagnosed diabetes, compared with those with prediabetes.
Endocrinology Advisor (4/18) 
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Ambulatory BP predicts mortality more accurately than clinical BP, study finds
A study in The New England Journal of Medicine found 24-hour ambulatory blood pressure measurements had a stronger association with all-cause mortality and cardiovascular mortality than clinical measurements. The findings, based on data for 63,910 adults from the Spanish Ambulatory Blood Pressure Registry over the period from 2004 to 2014, showed mortality was higher with masked hypertension, which refers to normal clinical readings but elevated ambulatory readings, than white-coat hypertension or sustained hypertension.
Healio (free registration)/Cardiology Today (4/18),  Family Practice News (4/18) 
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Study assesses link between asthma, lung function in teens born preterm
A study in Thorax found preschool wheeze was significantly more frequent among children born very prematurely. The findings, based on 304 adolescents born preterm and 47 children born at term, indicated bronchopulmonary dysplasia and prematurity were associated with lower lung function in adolescence, researchers said.
Pulmonology Advisor (4/18) 
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Single TBI may increase risk of Parkinson's disease
Veterans with any traumatic brain injury diagnosis, including concussion, were 71% more likely to develop Parkinson's disease, compared with those without TBI, with mild TBI tied to a 56% greater risk and moderate or severe TBI tied to an 83% higher risk of Parkinson's, according to a study in Neurology. The findings also showed that Parkinson's disease was diagnosed an average of two years earlier among those with TBI.
CNN (4/18),  HealthDay News (4/18) 
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Study links autonomy support to reduced distress in diabetes
Researchers used a cohort of 308 veterans with type 2 diabetes and found an association between diabetes distress and higher subsequent HbA1C levels, while autonomy support from family and friends was tied to lower HbA1C levels. Researchers said the findings, published in Diabetes Care, show that autonomy support may help reduce distress to lead to improved glycemic control.
Physician's Briefing/HealthDay News (4/18) 
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Pharmaceutical News
Heavy opiate use tied to premature death risk with IBD
UK researchers analyzed data for 8,866 patients with inflammatory bowel disease and found that patients with Crohn's disease who used strong opiates heavily were at an increased risk of premature mortality. Among those with ulcerative colitis, moderate or heavy use of strong opiates and heavy use of codeine were significantly associated with premature mortality, according to the study in Clinical Gastroenterology and Hepatology.
Physician's Briefing/HealthDay News (4/18) 
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Research compares efficacy of different classes of diabetes drugs
UK researchers analyzed 236 trials involving 176,310 patients with type 2 diabetes and found that SGLT-2 inhibitors and GLP-1 agonist drugs were associated with a 20% and 18% reduced mortality risk compared with placebo, respectively, while DPP-4 inhibitors were not. The findings in the Journal of the American Medical Association revealed that GLP-1 agonists and DPP-4 inhibitors increase natural insulin levels, while GLT-2 inhibitors increase the amount of sugar excreted by the body.
United Press International (4/18) 
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Emerging Trends, Products and Technologies
Report: About 40% of Americans exposed to unhealthy air
A report from the American Lung Association showed US counties with unhealthy ozone or particle pollution levels were occupied by about 133.9 million individuals from 2014 to 2016. Ozone pollution worsened because of warmer temperatures, but air quality and particulate matter have improved, according to the report.
United Press International (4/18) 
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Vt. leads US in pediatric health care
A WalletHub report ranked Vermont, the District of Columbia and Massachusetts as the top US states for pediatric health care, while Nevada, Louisiana and Texas were the worst. Vermont, Delaware, New Hampshire, Massachusetts and D.C. had the most pediatricians and family providers per capita, while New Hampshire, Washington, Colorado, Utah and Oregon had the lowest pediatric obesity rates.
U.S. News & World Report (4/18) 
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Health Policy and Legislative News
Senate bill calls for use of data, health IT to fight opioid crisis
Senate health committee leaders unveiled the Opioid Crisis Response Act of 2018, a bipartisan bill that includes measures increasing data collection, sharing and analysis, as well as reliance on EHR and telemedicine technology and Prescription Drug Monitoring Program databases. The legislation "could help states and communities begin to bring an end to the opioid crisis by reducing the number of prescription opioids, stopping illegal drugs at the border and accelerating research on non-addictive pain medicines," said committee chairman Sen. Lamar Alexander, R-Tenn.
Health Data Management (free registration) (4/18) 
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AANP announces National Leadership Award Recipients
AANP is pleased to announce recipients of the AANP 2018 National Leadership Awards. The awards will be presented during the opening general session at the AANP 2018 National Conference in Denver on June 27. The Towers Pinnacle Award is presented annually to an individual who, through policy, practice, or education, has made outstanding contributions resulting in increased national recognition for NPs and increased opportunities for NPs to provide care to patients. The 2018 Towers Pinnacle Award will be presented to Capt. James L. Dickens, DNP, RN, FNP-BC, FAANP, for his work as a commissioned officer in the U.S. Public Health Service. Capt. Dickens served as the Officer in Charge of the 76 member Public Health Service Ebola Response Team, which provided health care relief in Monrovia, Liberia-West Africa, overseeing local Ebola response efforts. The Sharp Cutting Edge Award is presented to an individual who has shown leadership through innovative services, technologies or advocacy activities that advanced NP practice and patient care on a national level. Angela Patterson, DNP, FNP-BC, NEA-BC, Chief Nurse Practitioner Officer for Minute Clinic and Vice President, CVS Health, is the recipient of the 2018 Sharp Cutting Edge Award. Dr. Patterson has consistently supported, strengthened and grown the NP workforce pipeline. She has transformed advanced practice nursing in this era of globalization through exemplary leadership and innovation, both nationally and internationally. View the news release for more information on the National Leadership Awards and the 2018 recipients.
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