How labs can improve delta check parameters | Tool predicts CV mortality risks | Genetic study explores mortality risk of Staphylococcus aureus
August 15, 2017
AACC SmartBrief
Top Story
How labs can improve delta check parameters
Delta checks are an important tool in detecting variances in patient-specific test results and misidentified specimens, and many labs are working to improve their delta check parameters. Among other things, labs revising their processes may benefit from the Clinical Laboratory Standards Institute's "Use of Delta Checks in the Medical Laboratory" document, according to this piece.
Clinical Laboratory News (8/2017) 
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Science Briefs
Tool predicts CV mortality risks
A clinical prediction model that includes the key biomarkers of N-terminal pro-B-type natriuretic peptide, high-sensitivity cardiac troponin T and low-density lipoprotein cholesterol can be used to predict cardiovascular death in patients with stable coronary heart disease, researchers wrote in the Journal of the American College of Cardiology. The final model also included age and clinical variables such as smoking, diabetes and peripheral arterial disease.
Physician's Briefing/HealthDay News (8/9) 
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Genetic study explores mortality risk of Staphylococcus aureus
Researchers from the Milner Center for Evolution at the University of Bath conducted a genome-wide association study of two strains of Staphylococcus aureus, CC22 and CC30, and analyzed patient records to identify factors associated with increased bacteraemia-associated mortality. Toxicity and biofilm forming capability were associated with mortality risk for the CC22 strain but not for CC30.
GenomeWeb Daily News (free registration) (8/8),  Genetic Engineering & Biotechnology News (8/8) 
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Tech Briefs
Novel Zika assay uses nanotechnology to deliver results in minutes
Washington University in St. Louis researchers developed a diagnostic test for the Zika virus that uses gold nanorods on paper that change color if the blood sample contains the pathogen, also yielding results in minutes, according to a study published in the journal Advanced Biosystems. No false-positive results were generated when the investigators tested the assay on four people infected with Zika compared with blood samples from five uninfected people.
Clinical Innovation + Technology online (8/11),  Drug Delivery Business News (8/11) 
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Scientists create TRI-Analyzer to transform smartphone into diagnostic device
A transmission-reflectance-intensity-Analyzer was developed by researchers at the University of Illinois at Urbana-Champaign to enable a smartphone's camera to analyze a diagnostic sample's colorimetric absorption spectrum, resonant reflection spectrum and fluorescence emission spectrum. This smartphone attachment illuminates the sample placed in a microfluidic cartridge using the phone's LED flash or a green laser, while the generated image is captured and analyzed by an app.
MedGadget (8/11) 
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Policy Briefs
CMS changes hospital MU attestation reporting for 2018
The CMS said it is changing how hospitals attest to EHR meaningful use in 2018, moving from the Medicare EHR Incentive Program Registration and Attestation System to the QualityNet Secure Portal. Medicare-only hospitals will be able to use the EHR Incentive Program Registration and Attestation System and Medicaid-only hospitals should contact their state agency for guidance on attestation, the CMS said.
Health Data Management (8/10) 
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Practice Briefs
Bloodstream infection system, assay from iCubate win FDA clearance
The FDA has given molecular diagnostics firm iCubate clearance for the iC-System and the iC-GPC assay for rapid detection of bloodstream infections-related pathogenic bacteria. The system and the in vitro diagnostic test take up to 48 hours less than other tests to deliver results, the company said.
360Dx (tiered subscription model) (8/10) 
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Business/Corporate Briefs
Hemex, Tata Elxsi team up on malaria, sickle cell test development
India-based Tata Elxsi has been tapped by Hemex Health to be its product design and engineering partner in the development of its point-of-care diagnostic device, Lab-in-a-Box. The product is an integration of sickle cell and malaria diagnostics and takes minutes to deliver results.
360Dx (tiered subscription model) (8/8) 
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Deal to sell 2.5M shares announced by Oxford Immunotec
A deal to sell 2.5 million ordinary shares was reached by diagnostic company Oxford Immunotec with investment bank BTIG. Net proceeds from the agreement, under which the company granted an option for the bank to buy up to 375,000 additional shares, will be used as working capital, as well as to support general corporate functions.
360Dx (tiered subscription model) (8/14) 
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Emerging Clinical & Laboratory Diagnostics in the Healthcare Ecosystem Conference
Nov. 9, 2017, San Diego, CA
Join AACC and discover the advances in emerging technologies in diagnostic tools while collaborating with scientists from non-clinical settings. Early bird registration ends Oct. 9.
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Mass Spectrometry and Separation Sciences for Laboratory Medicine 7th Annual Conference
Oct. 5, 2017, Philadelphia, PA
The 7th Annual Mass Spectrometry and Separation Sciences for Laboratory Medicine Conference will engage laboratory scientists, from trainees in clinical chemistry to laboratory directors and pathologists, on current and future clinical applications for mass spectrometry.
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