Once-daily vs twice-daily dosing for cancer pain
Chronic moderate to severe pain is an inevitable symptom associated with advanced stages of cancer, making alleviation of cancer pain an important pursuit. This article demonstrates clinical noninferiority of efficacy of once-daily hydromorphone extended-release compared with twice-daily oxycodone controlled-release in alleviating cancer pain in Chinese patients, with comparable safety profiles between the two treatment groups. This presents a treatment option with the potential for a reduced dosing frequency for health care providers and patients. The Journal of Pain
(8/2014) Share: 
Diagnosis and management of autosomal-recessive polycystic kidney disease
Autosomal-recessive polycystic kidney disease (ARPKD), a severe, typically early-onset form of cystic disease that primarily involves the kidneys and biliary tract, affects 1 in 20 000 live births. An international team of 25 multidisciplinary specialists from the U.S., Canada, Germany and the U.K. reviewed the literature from 1990 to 2013 and developed updated recommendations for diagnosis, surveillance and clinical management of ARPKD. The Journal of Pediatrics
(7/2014) Share:
Analysis of 70,000+ falls in nursing homes
Most serious falls in nursing homes occur in the morning among those who are more ambulatory, older and female. A Bavarian study looked at 70,000+ falls in a one-year period. 6 a.m. to 8 a.m. showed a more than 60% increased chance of transfer to hospital, demonstrating a more serious fall. More than 50% of falls were residents aged 80 to 89. 75% of the falls were in residents' rooms/bathrooms. Women 90+ with a fall led to a 50% increased risk of hospital transfers compared to those less than 70 years. (Free abstract only.) Journal of the American Medical Directors Association
(8/2014) Share:
Prenatal cocaine exposure links to attention problems
Adolescents prenatally exposed to cocaine reported more problems in attention and externalizing behaviors than noncocaine-exposed adolescents. These findings are consistent with neuroimaging studies, suggesting that prenatal cocaine exposure leads to alterations in behavioral domains of the prefrontal cortex. (Full-text access is time limited.) Journal of Adolescent Health
(8/2014) Share:
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CDC data suggest millions more Americans will develop diabetes
CDC data suggest that about 40% of Americans are expected to develop type 2 diabetes at some point during adulthood. Researchers noted higher estimates for certain minority groups, at 50% for black women and for Hispanic men and women. The results appear in The Lancet Diabetes & Endocrinology. HealthDay News
(8/13) Share:
Many meds commonly taken by elderly tied to greater risk of falls
An analysis of data on more than 64,000 people older than 65 in Sweden found that half of the 20 drugs most commonly prescribed to seniors were associated with a greater risk of falls. The link was strongest for painkillers and antidepressants, researchers said. The findings appeared in the European Journal of Public Health. Reuters
(8/12) Share:
Study rejects link between bisphosphonates, lower breast cancer risk
An analysis of data from two randomized studies found that bisphosphonate use does not appear to reduce the risk of developing breast cancer after menopause. The factor that reduces the risk could be low estrogen levels, said study author Trisha Hue. The findings, based on data involving about 14,200 women, were published in JAMA Internal Medicine. HealthDay News
(8/11) Share:
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Study: Virtual doctor visits rising rapidly
Deloitte estimates that there will be 75 million electronic visits to general practitioners in Canada and the U.S. this year, out of a total of 600 million appointments. Worldwide, there will be 100 million e-visits to doctors in 2014, the company forecasts. This is up 400% from 2012 and will provide more than $5 billion in savings, according to Deloitte. Computerworld
(8/8) Share:
Report looks at EHR adoption in U.S. hospitals
A Robert Wood Johnson Foundation report found that around 60% of U.S. acute-care hospitals have deployed at least a basic EHR. Among other findings, the report also revealed that 25.5% of U.S. hospitals had implemented a comprehensive EHR platform as of last year, and small hospitals are the least likely to implement a comprehensive EHR system. BeckersHospitalReview.com
(8/8) Share:
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8 ways patients use mHealth tools
Thirty-eight percent of consumers say they seek health information online, while 26% go online to arrange appointments, manage prescriptions or view lab results. One in 4 use a health application, and 22% use a device to monitor their health, according to a Parks Associates report. BeckersHospitalReview.com
(8/11) Share:
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The mind is not a vessel to be filled but a fire to be kindled."
-- Plutarch, Greek historian Share:
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