Ebola in the U.S.
Ebola virus caused an epidemic of unprecedented extension in West Africa, and there was concern the outbreak would not be controlled for a prolonged period of time. Two cases of infected returning travelers have been reported in the U.S. One has been associated with secondary transmission, and other infected subjects have been repatriated for treatment. This article reviews the etiology, pathogenesis, transmission, clinical manifestations, diagnosis, treatment, and prevention of the disease with emphasis on the identification and management in the U.S. The American Journal of Medicine
(7/2015) Share: 
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Trends in gestational diabetes mellitus prevalence
Diabetes is one of the most common and fastest-growing comorbidities of pregnancy. Deliveries in 19 states were examined for gestational diabetes mellitus (GDM) prevalence trends overall and by age, state, and region, and in 12 states by race/ethnicity. From 2000 through 2010, GDM deliveries increased significantly in all states, with relative increases ranging from 36% to 88%. In the 12 states reporting race and ethnicity, the highest relative increase in GDM deliveries was seen in Hispanic patients. Effective diabetes prevention and control strategies for women of childbearing age can help to protect the health of women and their newborns. (Available for CME credit.) American Journal of Preventive Medicine
(7/2015) Share:
Quality of life and Alagille syndrome
Alagille syndrome affects many body systems, including the liver, which can lead to a decreased health-related quality of life (HRQOL). Using the Childhood Liver Disease Research Network prospective study on cholestasis, questionnaires were completed by children with Alagille syndrome, alpha-1-antitrypsin deficiency, and chronic intrahepatic cholestasis, as well as their parents. HRQOL is impaired in children with Alagille syndrome, which is negatively associated with growth failure. The Journal of Pediatrics
(7/2015) Share:
Obstructive sleep apnea risk, asthma burden and lower airway inflammation in adults
Obstructive sleep apnea (OSA) may worsen asthma, but large studies are lacking and the underlying mechanisms are unknown. In this article the authors sought to determine the prevalence of OSA risk among patients with varying degrees of asthma severity compared to normal controls (NC). Subjects with severe and non-severe asthma and NC were recruited in an add-on sub-study to the observational Severe Asthma Research Program (SARP) II; subjects completed sleep quality, sleepiness, and OSA risk (Sleep Apnea scale of the Sleep Disorders Questionnaire [SA-SDQ]) questionnaires and clinical assessments. Asthmatic patients manifested higher SASDQ scores than NC, and higher SA-SDQ scores were associated with sputum neutrophilia and worse indices of asthma control, increased health care utilization and worse quality of life. The Journal of Allergy and Clinical Immunology: In Practice
(7/2015) Share:
Iron supplementation in chronic heart failure with anemia
Iron supplemention (iron dextran) improved exercise capacity in chronic heart failure, anemic rats by inhibiting sarcoplasmic vacuolation in the gastrocnemius muscle. Phospho-p38 was markedly suppressed, c-fos and c-jun levels reduced, cellular FLICE-inhibitory protein expression level up-regulated, and chronic-heart-failure-anemic−induced c-FLIPL protein expression reversed. Nutrition
(7/2015) Share:
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| Continuing Medical Education |
ACTRIMS-ECTRIMS 2014 Medical Meeting Reporter: A Scientific and Clinical Update on Current and Emergent Therapeutics within Multiple Sclerosis
This Elsevier Medical Meeting Reporter presents and summarizes important multiple sclerosis presentations and abstracts from the Joint Meeting of the American and European Committees for Treatment and Research of Multiple Sclerosis (ACTRIMS-ECTRIMS) Meeting hosted in Boston, Massachusetts. This meeting reporter focuses on the scientific and clinical updates that were presented by medical professionals, researchers and MS advocates striving to contribute to the care of individuals suffering with this disease. Many of the critical unanswered questions related to optimal use of pharmacotherapuetics are being addressed in clinical trials. While virtually all of this data is eventually published, the latest results are inevitably presented first as scientific presentations and posters at the 2014 Joint ACTRIMS-ECTRIMS meeting. This Elsevier Medical Meeting Reporter focuses on the pivotal sessions and key clinical data related to new treatment and standards of care of patients with multiple sclerosis to address physician knowledge in therapeutic selection and appropriate use of therapies. Elsevier CME Share:
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Longer sitting time linked to higher likelihood of cancer in women
Women who spend more of their leisure time sitting face a 10% greater risk of developing cancer, including invasive breast cancer, ovarian cancer and multiple myeloma. The study, published in the journal Cancer Epidemiology, Biomarkers & Prevention, failed to find the same link in men. The study controlled for overall physical activity, and experts said the findings were puzzling but underscore the need to reduce sedentary time. HealthDay News
(7/14) Share:
Family history of celiac disease linked to greater risk of diabetes, lupus
A study published in the journal Clinical Gastroenterology and Hepatology found that first-degree relatives, as well as spouses, of celiac disease patients have a higher likelihood of developing autoimmune disorders including type 1 diabetes, lupus and rheumatoid arthritis. During the 11-year study, over 4% of first-degree relatives developed a nonceliac autoimmune disease, compared with a little over 3% of people who had no relation to a celiac patient. HealthDay News
(7/10) Share:
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Study: Readmission rates similar for weekend, weekday discharge
A study published in the Journal of Hospital Medicine found that the 30-day readmission rate for congestive heart failure patients discharged on weekends was 15.4%, compared with 16% for patients discharged on weekdays. Researchers report readmission rates for patients hospitalized with acute myocardial infarction or pneumonia patients were also similar, regardless of whether they were discharged on weekends or weekdays. Data were gathered from 266,519 patients in California. PhysiciansBriefing.com/HealthDay News
(7/10) Share:
Report outlines 12 factors to consider during EHR implementation
A Hayes Management Consulting report outlines 12 items that health care organizations should consider to successfully roll out an EHR system. According to Hayes, the cost of developing every individual application module that will make up the EHR system should be estimated, as some of these tools may cost more to complete than others. The report also recommends that organizations consider additional compensation for doctors who take on tasks to help support the implementation of the EHR. Health Data Management
(7/12), BeckersHospitalReview.com
(7/13) Share:
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Few U.S. states require HPV vaccine, study finds
Only Washington, D.C., Virginia and Rhode Island mandate human papillomavirus vaccination, but most states require vaccines against chickenpox, hepatitis B and meningitis for preteens and teenagers, according to a study in the Journal of the American Medical Association. Data from the CDC showed that only 38% and 14% of teenage girls and boys, respectively, received all three doses of the HPV vaccine in 2013. HealthDay News
(7/14), Reuters
(7/14) Share:
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Too much rest is rust."
-- Walter Scott, novelist, playwright and poet Share:
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