Antidepressant use and cognitive decline | Athletic performance and antioxidants | Tool to predict opioid misuse in chronic pain patients
 
 
July 9, 2015
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Antidepressant use and cognitive decline
Depression is associated with cognitive impairment and dementia, but whether treatment for depression with antidepressants reduces the risk for cognitive decline is unclear. The authors assessed the association between antidepressant use and cognitive decline over six years. The American Journal of Medicine (7/2015) Share: Email
 
Clinical Updates
Athletic performance and antioxidants
Athletic performance and antioxidants are examined in this review, with the conclusion that training, adaptation, and genetic factors are enhanced by addressing oxidative stress nutritionally. Increasingly, it is apparent that a personalized and adaptive approach is needed. Antioxidant supplementation is sometimes, but not always, beneficial. A diet rich in fruits and vegetables, as part of a personalized plan, is likely the best approach. Nutrition (7/2015) Share: Email
 
Tool to predict opioid misuse in chronic pain patients
The Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) predicts increased risk of opioid misuse in chronic pain patients. The authors evaluated whether higher SOAPP-R scores are associated with greater opioid reinforcing properties, potentially contributing to their predictive utility. Results indicate that the SOAPP-R may predict elevated opioid risk in part by tapping into individual differences in opioid reinforcing effects. Based on placebo-controlled morphine responses, associations were observed between higher scores on the SOAPP-R and greater desire to take morphine again, fewer negative subjective morphine effects, and greater analgesia. Opioids may provide the best analgesia in those patients at greatest risk of opioid misuse. The Journal of Pain (7/2015) Share: Email
 
'Omics data in the perinatal context
Functional analysis of fetal transcriptomic datasets varies according to whether or not the resource has been specifically annotated for developmental processes. American Journal of Obstetrics & Gynecology (7/2015) Share: Email
 
Impaired arousal and length of hospital stay
Is your hospitalized elderly patient difficult to wake up? Impaired arousal while an older person is hospitalized may be an indicator of a prolonged hospital stay and may predict discharge to a skilled nursing facility. Impaired arousal can produce negative outcomes such as delirium, falls, pressure ulcers, and functional decline. This study from the Southeastern United States found that on any random day patients with impaired arousal had 27% lower opportunity for discharge. Journal of the American Medical Directors Association (7/2015) Share: Email
 
Effectiveness of different defibrillator types
In a large Medicare population, cardiac resynchronization therapy defibrillators were associated with lower mortality in left bundle branch block, but higher mortality in right bundle branch block. The absence of certain covariates, in particular those that determine treatment selection, may affect the results of comparative effectiveness studies using claims data. The American Journal of Cardiology (7/1/2015) Share: Email
 
White children may be at a higher risk for brain tumors associated with NF1
Neurofibromatosis type 1 (NF1) is associated with severe clinical manifestations, such as benign and malignant tumors. It was recently suggested the birth incidence may be as high as 1 in 2,000. To determine whether pediatric brain tumors related to NF1 varied by race/ethnicity, this cross-sectional study assessed children from the NF1 Patient Registry Initiative, clinical records, and databases. This study suggests that pediatric brain tumors vary by race/ethnicity in children with NF1, with black and Asian children having reduced odds compared with white children. The Journal of Pediatrics (7/2015) Share: Email
 
Medical News
Multiple chronic diseases increase premature death risk eightfold
Researchers found that patients with a combination of diabetes, heart disease and stroke have a shorter life expectancy by up to 15 years. Patients age 60 years and older who have two cardiometabolic risk conditions lose 12 years of life, while smokers cut 10 to 11 years from their expected life span. The study was published in the Journal of the American Medical Association. HealthDay News (7/7) Share: Email
Diet high in vitamin C may reduce cardiovascular risk, study says
People who ate the most fruits and vegetables, which led to high blood levels of vitamin C, reduced their risk of cardiovascular disease by 15% and their likelihood of early death by 20%, compared with people who ate the fewest fruits and vegetables, researchers reported in the American Journal of Clinical Nutrition. The study included data from about 100,000 people in Denmark. Science World Report (7/7) Share: Email
Study: Patient risks do not increase when residents assist surgery
The participation of medical residents during brain or spine surgery does not raise patients' risks for complication or death, researchers from Johns Hopkins Hospital reported in the Journal of Neurosurgery. The study included information on 16,000 brain and spine surgeries from the American College of Surgeons National Surgical Quality Improvement Program database. HealthDay News (7/6) Share: Email
Business Practice News
Survey: Most doctors continue working while sick despite risk to patients
A survey of 480 attending physicians and 256 advanced practice clinicians found that while nearly all respondents believe working while sick raises potential risk for patients, 83% revealed they still went to work while feeling ill at least once in the last year. Doctors who worked while they were sick expressed concern over continuity of patient care and professional responsibility, with 98% of respondents worried about their co-workers and 94% citing staffing concerns. Findings were published in JAMA Pediatrics. United Press International (7/6) Share: Email
ICD-10 end-to-end testing resulted in 90% claim acceptance
A total of 90% of claims submitted by over 1,200 volunteers during ICD-10 end-to-end testing held from June 1 to 5 were accepted by the CMS. An analysis found most of the rejected claims were due to errors not related to ICD-10 coding. An additional guidance was also released by the CMS with the American Medical Association to inform providers that claims will not be denied for a year after ICD-10 implementation on Oct. 1 so long as a valid code is used. Healthcare Informatics online (7/6) Share: Email
Patient's Perspective
Survey reveals most U.S. adults trying to reduce sodium intake
Just over 50% of more than 180,000 adults across the U.S. said they are watching or reducing their daily sodium or salt intake, according to a survey published in CDC's Morbidity and Mortality Weekly Report. Researchers found that efforts to reduce salt intake were highest in areas with high rates of high blood pressure. HealthDay News (7/2) Share: Email
SmartQuote
Fear builds walls to bar the light."
-- Baal Shem Tov,
rabbi Share: Email
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